scholarly journals Reference Values of Right Ventricular Volumes and Ejection Fraction by Three-Dimensional Echocardiography in Adults: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 8 ◽  
Author(s):  
Shitong Wang ◽  
Shuyu Wang ◽  
Qing Zhu ◽  
Yonghuai Wang ◽  
Guangyuan Li ◽  
...  
Keyword(s):  
Systematic Review ◽  
Reference Values ◽  
Meta Analysis ◽  
Three Dimensional ◽  
Systolic Pressure ◽  
Frame Rate ◽  
Pulmonary Artery Systolic Pressure ◽  
Specific Reference ◽  
Systolic Volume ◽  
End Diastolic Volume

Objective: This study was conducted in order to determine the reference values for right ventricular (RV) volumes and ejection fraction (EF) using three-dimensional echocardiography (3DE) and to identify sources of variance through a systematic review and meta-analysis.Methods: This systematic review was preregistered with the International Prospective Register of Systematic Reviews (https://www.crd.york.ac.uk/PROSPERO/) (CRD42020211002). Relevant studies were identified by searches of the PubMed, Embase, and Cochrane Library databases through October 12, 2020. Pooled reference values were calculated using the random-effects model weighted by inverse variance. Meta-regression analysis and Egger's test were used to determine the source of heterogeneity. A subgroup analysis was performed to evaluate the reference values across different conditions.Results: The search identified 25 studies of 2,165 subjects. The mean reference values were as follows: RV end-diastolic volume, 100.71 ml [95% confidence interval (CI), 90.92–110.51 ml); RV end-systolic volume, 44.19 ml (95% CI, 39.05–49.33 ml); RV end-diastolic volume indexed, 57.01 ml/m2 (95% CI, 51.93–62.08 ml/m2); RV end-systolic volume indexed, 25.41 ml/m2 (95% CI, 22.58–28.24 ml/m2); and RVEF, 56.20% (95% CI, 54.59–57.82%). The sex- and age-specific reference values were assessed according to the studies reporting the values of different sexes and age distributions, respectively. In addition, the vendor- and software-specific reference values were analyzed. The meta-regression analysis revealed that sex, frame rate, pulmonary artery systolic pressure, and software packages were associated with variations in RV volumes (P < 0.05). Inter-vendor and inter-software discrepancies may explain the variability of RVEF.Conclusions: The reference values for RV volumes and RVEF using 3DE were assessed. The confounders that impacted the variability in RV volumes or RVEF contained the sex, frame rate, pulmonary artery systolic pressure, inter-vendor discrepancies, and inter-software discrepancies.

P5581In patients with aortic valve regurgitation, left ventricular geometry and strain, more than pulmonary artery systolic pressure, affect right ventricular function

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
H Abdelgawad ◽  
M A Abdelhay ◽  
S Ashour ◽  
M Shehata ◽  
M Previato ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Right Ventricular ◽  
Systolic Pressure ◽  
Left Ventricular ◽  
Pulmonary Artery Systolic Pressure ◽  
Systolic Volume ◽  
End Diastolic Volume ◽  
Sphericity Index ◽  
End Systolic Volume ◽  
Rv Function

Abstract Background Left ventricular (LV) overload due to aortic valve (AR) regurgitation may affect right ventricular (RV) function. Elevation of pulmonary artery pressures secondary to isolated AR is not common. Thus, the effects of chronic LV overload due to AR on RV function remains to be clarified. Purpose To assess the determinants of RV dysfunction in chronic AR. Methods We studied 36 patients with moderate or severe AR (53±18 years, 81% were men). We used 3D echocardiography to acquire multi-beat, full-volume data sets of LV and RV and to measure volumes and EF. RV fractional area change (FAC) was calculated. LV global longitudinal strain (GLS) and RV peak longitudinal strain (RVLS) were assessed by 2D speckle tracking echocardiography. Results RV EF and RV FAC were 40±6% and 34±9%. LV GLS and peak RVLS were reduced (Table). LV EDVi showed negative correlations with RV function (RV EF: r=−0.545, p<0.001; RV FAC: r=−0.816, p<0.001). LV sphericity index showed negative correlations with RV function (RVFAC: r=−0.608, P=0.001; RV EF: r=−0.469, P=0.004). Moreover, LV GLS and RVLS correlated positively with RV function (FAC: for GLS: r=0.475, p=0.003 and for RVLS: r=0.389, p=0.019) (RV EF: for GLS: r=0.526, p=0.001 and for RVLS: r=0.475, p=0.003). On multivariable linear regression analysis, LV EDVi, LV sphericity index, LV GLS and peak RVLS were found to be the only independent predictors of RV EF and FAC. Left and right ventricular volumes and function in patients with chronic aortic regurgitation AR (n=36) Control (n=25) p value LV end-diastolic volume (ml/m2) 106±36 56±8 <0.001 LV end-systolic volume (ml/m2) 50±28 22±4 <0.001 LV ejection fraction (%) 54±10 60±4 <0.001 LV sphericity index 0.53±0.11 0.38±0.08 <0.001 Pulmonary artery systolic pressure (mm Hg) 27±8 RV end-diastolic volume (ml/m2) 59±12 35±7 <0.001 RV end-systolic volume (ml/m2) 31±9 17±3 <0.001 RV ejection fraction (%) 40±6 50±4 <0.001 RV fractional area change (%) 34±9 44±6 <0.001 LV GLS (%) −18±3 21±1 <0.001 Peak RVLS (%) −26±5 −31±3 <0.001 Conclusions RV remodeling in chronic LV overload due to AR occurs independent on PASP values. LV size, shape and strain are the only independent predictors of RV function.

Three-dimensional virtual planning for nodule resection in solid organs: A systematic review and meta-analysis

2021 ◽  
pp. 101598
Author(s):  
Matheus Zanon ◽  
Stephan Altmayer ◽  
Guilherme Watte ◽  
Gabriel Sartori Pacini ◽  
Tan-Lucien Mohammed ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Three Dimensional ◽  
Virtual Planning

scholarly journals Establishing reference values for age-related spermatogonial quantity in prepubertal human testes: a systematic review and meta-analysis

2016 ◽  
Vol 106 (7) ◽  
pp. 1652-1657.e2 ◽  
Author(s):  
Ieva Masliukaite ◽  
Julie M. Hagen ◽  
Kirsi Jahnukainen ◽  
Jan-Bernd Stukenborg ◽  
Sjoerd Repping ◽  
...  
Keyword(s):  
Systematic Review ◽  
Reference Values ◽  
Meta Analysis ◽  
Age Related

Normative Reference Values of Right Heart in Competitive Athletes: A Systematic Review and Meta-Analysis

2017 ◽  
Vol 30 (9) ◽  
pp. 845-858.e2 ◽  
Author(s):  
Flavio D'Ascenzi ◽  
Antonio Pelliccia ◽  
Marco Solari ◽  
Pietro Piu ◽  
Ferdinando Loiacono ◽  
...  
Keyword(s):  
Systematic Review ◽  
Reference Values ◽  
Meta Analysis ◽  
Right Heart ◽  
Competitive Athletes

scholarly journals Management of Instrument Sterilization Workflow in Endodontics: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-20 ◽  
Author(s):  
Mario Dioguardi ◽  
Diego Sovereto ◽  
Gaetano Illuzzi ◽  
Enrica Laneve ◽  
Bruna Raddato ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Three Dimensional ◽  
Qualitative And Quantitative Analysis ◽  
Pulp Chamber ◽  
Qualitative And Quantitative ◽  
Operating Field ◽  
Gutta Percha ◽  
Single Use ◽  
Dental Burs

Endodontic treatment consists of different working procedures, such as the isolation of the operating field, pulp chamber access, and cleaning and shaping phases with at last the need of a three-dimensional filling of the canals. Each step requires a series of single-use or sterilizable instruments. We have performed a systematic review of different sterilization and disinfection procedures aiming at drawing up a disinfection and sterilization procedure to be used on endodontic instruments. A search on PubMed and Scopus was carried out using the following keywords: “endodontic sterilization,” “endodontic autoclave,” “decontamination dental bur,” “sterilization dental burs,” and “gutta-percha points sterilization.” Eligible articles were included in the qualitative and quantitative analysis. Results of the meta-analysis showed that the most effective method in sterilization is autoclaving. The qualitative analysis showed that the use of single-use or first-use instruments requires presterilization or sterilization procedures, and for reusable tools, attention must be paid to the removal of debris deposited on the blades, not easy to remove manually.

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