Normative Reference Values of Right Heart in Competitive Athletes: A Systematic Review and Meta-Analysis

The present systematic review of observational studies with meta-analysis aim to identify the reference values of the spinal curvatures in the sagittal plane, as evaluated using the Cobb angle in X-rays, in healthy individuals. Electronic searches were undertaken in MEDLINE, Scopus, ScienceDirect and LILACS. Studies that evaluated the spinal curvature of healthy children, adolescents, adults, and elderly using Cobb method and presented reference values for those curvatures were incluced. Thirty-one studies were eligible for inclusion. The reference values found (confidence interval 95%) were: for children, thoracic (28.7°-37.9°), lumbar L1-L5 (34.5o-44.8º), and lumbar L1-S1 (41.7o-54.1o); for adolescents: thoracic (31.5o-39.2o), lumbar L1-L5 (39.8o-45.6o), and lumbar L1-S1 (51.9o-59.1o); for adults: thoracic (33.7o-40.3o), lumbar L1-L5 (38.1o-45.6o), and lumbar L1-S1 (54.2o-61.7o); and for the elderly: thoracic (37.7º-50.4o), and lumbar L1-S1 (56.6º-65.9o). For the cervical region, it was impossible to establish consistent reference values. The present study supports that precise reference intervals were identified for the sagittal curvatures of the thoracic and lumbar spine in healthy children, adolescents, adults and elderly, as evaluated by means of the Cobb Method.

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Comparative accuracy of non-invasive imaging versus right heart catheterization for the diagnosis of pulmonary hypertension: A systematic review and meta-analysis

IJC Heart & Vasculature ◽

10.1016/j.ijcha.2020.100568 ◽

2020 ◽

Vol 29 ◽

pp. 100568

Author(s):

Waqas Ullah ◽

Artem Minalyan ◽

Sameer Saleem ◽

Nayab Nadeem ◽

Hafez M. Abdullah ◽

...

Keyword(s):

Systematic Review ◽

Pulmonary Hypertension ◽

Meta Analysis ◽

Right Heart Catheterization ◽

Heart Catheterization ◽

Right Heart ◽

Non Invasive ◽

Comparative Accuracy

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Reference values of rotational thromboelastometry in pregnancy and parturition: a systematic review and meta-analysis

Anesteziologiya i Reanimatologiya ◽

10.17116/anaesthesiology202103128 ◽

2021 ◽

pp. 28

Author(s):

A.M. Ronenson ◽

E.M. Shifman ◽

A.V. Kulikov ◽

Yu.S. Raspopin

Keyword(s):

Systematic Review ◽

Reference Values ◽

Meta Analysis ◽

Rotational Thromboelastometry ◽

In Pregnancy

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Prognostic significance of right heart thrombi (RHT) in patients with acute symptomatic pulmonary embolism: Systematic review and meta-analysis

10.1183/13993003.congress-2016.pa3608 ◽

2016 ◽

Author(s):

Deisy Barrios Barreto ◽

Vladimir Rosa-Salazar ◽

Raquel Morillo Guerrero ◽

David Jimenez Castro ◽

Rosa NietoRoyo ◽

...

Keyword(s):

Systematic Review ◽

Pulmonary Embolism ◽

Meta Analysis ◽

Prognostic Significance ◽

Right Heart ◽

Symptomatic Pulmonary Embolism

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Accuracy of Pulse Wave Velocity Predicting Cardiovascular and All-Cause Mortality. A Systematic Review and Meta-Analysis

Journal of Clinical Medicine ◽

10.3390/jcm9072080 ◽

2020 ◽

Vol 9 (7) ◽

pp. 2080

Author(s):

Irene Sequí-Domínguez ◽

Iván Cavero-Redondo ◽

Celia Álvarez-Bueno ◽

Diana P Pozuelo-Carrascosa ◽

Sergio Nuñez de Arenas-Arroyo ◽

...

Keyword(s):

Systematic Review ◽

Arterial Stiffness ◽

Pulse Wave Velocity ◽

Wave Velocity ◽

Reference Values ◽

Cardiovascular Mortality ◽

Pulse Wave ◽

Meta Analysis ◽

Predictive Performance ◽

All Cause Mortality

Increased arterial stiffness has been associated with an increased risk of developing cardiovascular diseases and all-cause mortality. Pulse wave velocity (PWV) is an innovative and affordable measurement of arterial stiffness which may be an accessible tool to estimate mortality risk; however, no meta-analysis has estimated its predictive performance for cardiovascular and all-cause mortality. Moreover, reference values for PWV have only been established by consensus for healthy populations. The aim of this review was to estimate PWV and especially carotid femoral PWV performance predicting cardiovascular and all-cause mortality as well as comparing the resulting cfPWV thresholds with already established values in order to increase its validity. Original studies measuring PWV thresholds and its association with cardiovascular and all-cause mortality were systematically searched. The DerSimonian and Laird method was used to compute pooled estimates of diagnostic odds ratio (dOR), and overall test performances were summarized in hierarchical summary receiver operating characteristic curves (HSROC). Six studies were included in the meta-analysis. The pooled dOR values for the predictive performance of cfPWV were 11.23 (95 % CI, 7.29–1.29) for cardiovascular mortality and 6.52 (95% CI, 4.03–10.55) for all-cause mortality. The area under the HSROC curve for cfPWV was 0.75 (95% CI, 0.69–0.81) for cardiovascular mortality and 0.78 (95% CI, 0.74–0.83) for all-cause mortality, where the closest cut-off point to the summary point was 10.7 and 11.5, respectively. This systematic review and meta-analysis demonstrates that cfPWV is a useful and accurate cardiovascular mortality predictor and that its previously estimated reference values for estimating risk may be used in high-risk populations.

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P4127CMR normal reference values of biventricular size and function in male athletes

European Heart Journal ◽

10.1093/eurheartj/ehz745.0699 ◽

2019 ◽

Vol 40 (Supplement_1) ◽

Author(s):

F D'Ascenzi ◽

F Anselmi ◽

P Piu ◽

C Fiorentini ◽

M Focardi ◽

...

Keyword(s):

Reference Values ◽

English Language ◽

Ventricular Remodeling ◽

Meta Analysis ◽

Phenotypic Expression ◽

Training Volume ◽

Normal Limits ◽

Normal Reference ◽

Competitive Athletes ◽

And Function

Abstract Background Exercise-induced enlargement of cardiac chambers is commonly observed in competitive athletes. However, ventricular dilatation is also a common phenotypic expression of life-threatening cardiomyopathies. The use of cardiac magnetic resonance (CMR) for the exclusion of pathology is growing. However, normal reference values have not been established for athletes. The aim of this meta-analysis was to derive normal reference values of biventricular size and function estimated by CMR in competitive athletes. Methods We conducted a systematic review of English-language studies in the MEDLINE, Scopus, and Cochrane databases investigating biventricular size and function by CMR in athletes. Athletes were divided into endurance, combined, and mixed groups according to the sport practiced. The potential impact of training volume was also evaluated. Results Twenty-seven studies and 983 competitive athletes were included for CMR quantification of biventricular size and function. In this review, normal reference values are presented for biventricular size and function to be applied to male competitive athletes according to the disciplines practiced. A significant impact of training volume was demonstrated for the right ventricle: athletes practicing the largest number of training hours per week were those exhibiting the greatest degree of right ventricular remodeling (Figure 1). Notably, biventricular function was not significantly affected by training volume. Figure 1 Conclusions The present meta-analysis defines the normal limits of biventricular size and function estimated by CMR in competitive athletes. The authors suggest using these normal reference values as an alternative to standard upper limits derived from the general population when interpreting CMR images in athletes.

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