scholarly journals Factors Affecting Volume Changes of the Somatosensory Cortex in Patients with Spinal Cord Injury: To Be Considered for Future Neuroprosthetic Design

2017 ◽  
Vol 8 ◽  
Author(s):  
Yvonne Höller ◽  
Arijan Tadzic ◽  
Aljoscha C. Thomschewski ◽  
Peter Höller ◽  
Stefan Leis ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Somatosensory Cortex ◽  
Volume Changes ◽  
Factors Affecting ◽  
Cord Injury

scholarly journals An assessment of factors affecting neurological recovery after spinal cord injury with vertebral fracture

Spinal Cord ◽  
1996 ◽  
Vol 34 (3) ◽  
pp. 164-166 ◽  
Author(s):  
P Bravo ◽  
C Labarta ◽  
M A Alcaraz ◽  
J Mendoza ◽  
A Verdú
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Vertebral Fracture ◽  
Neurological Recovery ◽  
Factors Affecting ◽  
Cord Injury

scholarly journals Selected factors affecting the efficiency of wheelchair mobility in individuals with spinal cord injury

2016 ◽  
Vol 30 (2) ◽  
pp. 5-15
Author(s):  
Grzegorz Przysada ◽  
Justyna Wyszyóska ◽  
Mariusz Drużbicki ◽  
Anna Pajda ◽  
Justyna Leszczak ◽  
...  
Keyword(s):  
Physical Activity ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Injury Rehabilitation ◽  
Factors Affecting ◽  
Cord Injury ◽  
Medium Level ◽  
Wheel Chair ◽  
Active Rehabilitation ◽  
Complete Spinal Cord Injury

Abstract Introduction: Locomotion efficiency levels in individuals with spinal cord injury deal cord injury depend upon the level of spinal cord injury. Rehabilitation of people with spinal cord injury aims to prepare them to function in society in the best possible manner. One of the significant tasks of rehabilitation is to develop the skill of moving in a wheelchair, which becomes the only means of locomotion for most people. The aim of the study was to assess the influence of selected factors such as age, sex, time from the occurrence of the injury, the level of spinal cord injury, participation in Active Rehabilitation camps and the level of physical activity on the efficiency of locomotion in a wheelchair in individuals with spinal cord injury. Material and methods: The study included 55 patients after a complete spinal cord injury (39 males and 16 females using manual wheelchairs), aged 19 to 59. The level of spinal cord injury was assessed on the basis of a subjective classification of ASIA. The efficiency of wheelchair mobility was evaluated using the wheelchair manoeuvring technique test by Tasiemski (evaluation of performance of 14 tasks taking into account architectural barriers). Results: The majority of respondents (n = 28) obtained medium level of the efficiency, 16 participants scored low, while 11 individuals scored high. The highest score which women obtained was the medium level. It was men only (n = 11) who scored high. There was no statistically significant correlation between the efficiency of wheel-chair mobility and the level of spinal cord injury. It was observed that younger individuals and those practising sport daily achieved the best test results. Conclusions: Participants’ age affected their locomotion efficiency in a wheelchair. Females demonstrated lower levels of efficiency wheelchair mobility than their male counterparts. Regular physical activity affected the participants’ efficiency of wheeled mobility significantly.

Absence of localized grey matter volume changes in the motor cortex following spinal cord injury

2004 ◽  
Vol 1028 (1) ◽  
pp. 19-25 ◽  
Author(s):  
Adrian Philip Crawley ◽  
Michael Todd Jurkiewicz ◽  
Annabella Yim ◽  
Sujiva Heyn ◽  
Mary Caroline Verrier ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Motor Cortex ◽  
Grey Matter ◽  
Grey Matter Volume ◽  
Volume Changes ◽  
Matter Volume ◽  
Cord Injury

scholarly journals The Main Factors Affecting the Acceptance and Adaptation With Spinal Cord Injury: A Qualitative Study

2019 ◽  
pp. 276-291 ◽  
Author(s):  
Mohammad Saeed Khanjani ◽  
Hamid Reza Khankeh ◽  
Seyed Jalal Younesi ◽  
Manouchehr Azkhosh
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Qualitative Study ◽  
Factors Affecting ◽  
Cord Injury ◽  
Main Factors

scholarly journals Heparin-Binding Growth-Associated Molecule (Pleiotrophin) Affects Sensory Signaling and Selected Motor Functions in Mouse Model of Anatomically Incomplete Cervical Spinal Cord Injury

2021 ◽  
Vol 12 ◽  
Author(s):  
Natalia Kulesskaya ◽  
Dmitry Molotkov ◽  
Sonny Sliepen ◽  
Ekaterina Mugantseva ◽  
Arturo Garcia Horsman ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Neurite Outgrowth ◽  
Somatosensory Cortex ◽  
Intrathecal Injection ◽  
Axon Growth ◽  
Heparin Binding ◽  
Motor Functions ◽  
Cord Injury ◽  
Sensory Signaling

Heparin-binding growth-associated molecule (pleiotrophin) is a neurite outgrowth-promoting secretory protein that lines developing fiber tracts in juvenile CNS (central nervous system). Previously, we have shown that heparin-binding growth-associated molecule (HB-GAM) reverses the CSPG (chondroitin sulfate proteoglycan) inhibition on neurite outgrowth in the culture medium of primary CNS neurons and enhances axon growth through the injured spinal cord in mice demonstrated by two-photon imaging. In this study, we have started studies on the possible role of HB-GAM in enhancing functional recovery after incomplete spinal cord injury (SCI) using cervical lateral hemisection and hemicontusion mouse models. In vivo imaging of blood-oxygen-level-dependent (BOLD) signals associated with functional activity in the somatosensory cortex was used to assess the sensory functions during vibrotactile hind paw stimulation. The signal displays an exaggerated response in animals with lateral hemisection that recovers to the level seen in the sham-operated mice by injection of HB-GAM to the trauma site. The effect of HB-GAM treatment on sensory-motor functions was assessed by performance in demanding behavioral tests requiring integration of afferent and efferent signaling with central coordination. Administration of HB-GAM either by direct injection into the trauma site or by intrathecal injection improves the climbing abilities in animals with cervical hemisection and in addition enhances the grip strength in animals with lateral hemicontusion without affecting the spontaneous locomotor activity. Recovery of sensory signaling in the sensorimotor cortex by HB-GAM to the level of sham-operated mice may contribute to the improvement of skilled locomotion requiring integration of spatiotemporal signals in the somatosensory cortex.

Reorganization of Somatosensory Cortex After Nerve and Spinal Cord Injury

Physiology ◽  
1998 ◽  
Vol 13 (3) ◽  
pp. 143-149 ◽  
Author(s):  
Neeraj Jain ◽  
Sherre L. Florence ◽  
Jon H. Kaas
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Peripheral Nerve ◽  
Somatosensory Cortex ◽  
Tonic Inhibition ◽  
Synaptic Efficacy ◽  
Spinal Lesions ◽  
Mature Brain ◽  
Cord Injury ◽  
Neuronal Sprouting

Somatotopic maps in the mature brain reorganize in response to deafferentation by peripheral nerve cut, amputations, or spinal lesions. Mechanisms underlying these changes may range from altered tonic inhibition and synaptic efficacy to neuronal sprouting. An understanding of these mechanisms could guide interventions that potentiate recovery from such injuries.

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