scholarly journals A Pilot Study: N-Staging Assessment of Shear Wave Elastrography in Small Cervical Lymph Nodes for Nasopharyngeal Carcinoma

2020 ◽  
Vol 10 ◽  
Author(s):  
Ying Guan ◽  
Shuai Liu ◽  
An-Chuan Li ◽  
Xin-Bin Pan ◽  
Zhong-Guo Liang ◽  
...  
1990 ◽  
Vol 104 (1) ◽  
pp. 41-42 ◽  
Author(s):  
S. Elango ◽  
C. R. Jayakumar

AbstractRecent reports have dispelled the previously held concept that head and neck cancer rarely metastases beyond the cervical lymph nodes. Nasopharyngeal cancer has been reported to have a higher incidence of distant metastases compared to other head and neck cancers, the common sites being bone, lung and liver. A case of nasopharyngeal carcinoma presenting as obstructive jaundice because of secondaries at the porta hepatis is presented here.


2019 ◽  
Vol 48 (6) ◽  
pp. 20180454 ◽  
Author(s):  
Yoshihiko Sasaki ◽  
Ichiro Ogura

Objectives: To evaluate shear wave elastography in differentiating between benign and malignant cervical lymph nodes in patients with oral carcinoma. Methods: 77 patients with oral squamous cell carcinoma were examined by B-mode and shear wave elastography with a 14 MHz linear transducer. The integrated shear wave elastography software allowed the operator to place regions of interest of various sizes within the elastography window, and automatically displayed shear elastic modulus data (kPa) for each region of interest. The relationship between size and shear elastic modulus of cervical lymph nodes was assessed by Pearson's rank correlation test. The shear elastic modulus of cervical lymph nodes in benign and malignant were evaluated using the Mann–Whitney U test. The analyses were used with a 5% significance level. Results: We plotted shear elastic modulus (X) against minimal axial diameter of cervical lymph nodes (Y), and observed a significant correlation [ Y = 0.091 X + 4.648 (R2 = 0.603, p = 0.000, N = 77)]. Furthermore, the shear elastic modulus of the malignant cervical lymph nodes (105.9 ± 5.2 kPa) was higher than that of benign (11.9 ± 4.4 kPa, p = 0.000). Conclusions: The shear wave elastography is an effective technique for the objectively and quantitatively diagnosis of cervical lymph node metastases of the oral carcinoma.


2017 ◽  
Vol 45 (2) ◽  
pp. 251-259 ◽  
Author(s):  
Jun You ◽  
Juan Chen ◽  
Feixiang Xiang ◽  
Yue Song ◽  
Simai Khamis ◽  
...  

2012 ◽  
Vol 38 (2) ◽  
pp. 195-201 ◽  
Author(s):  
Kunwar S.S. Bhatia ◽  
Carmen C.M. Cho ◽  
Cina S.L. Tong ◽  
Edmund H.Y. Yuen ◽  
Anil T. Ahuja

2020 ◽  
Author(s):  
Lijun Wang ◽  
Shengfu Huang ◽  
Lanfang Zhang ◽  
Xia He ◽  
Yatian Liu

Abstract Purpose: To recommend a cranial border for level IIb in delineating clinical target volumes (CTV) for nasopharyngeal carcinoma (NPC) patients receiving intensity-modulated radiotherapy and to help reach a consensus on contouring level IIb in CTV.Methods: From 2012 to 2016, 331 nonmetastatic NPC patients treated with IMRT were retrospectively enrolled. Based on the AJCC 8th staging system of NPC, there were 15 stage I, 76 stage II, 103 stage III, and 137 stage IV patients. The distribution of cervical lymph nodes in NPC was assessed based on imaging. Comparisons of the safety and parotid dose parameters between patients with and without a reduction in the size of level IIb were conducted using SPSS 25.0 and R 2.14.2 software.Results: Metastasis rates in the most commonly involved lymph nodes, the lateral retropharyngeal and IIb nodes, were 82.8% and 64.0%, respectively. Among patients with level IIb involvement, the upper borders of the metastatic nodes were beyond the caudal edge of C1 in 13.7% of cases. The parotid gland D50 and V26 values were significantly reduced after modifying the upper bound of level IIb used to delineate the CTV (P = 0. 000).Conclusion: In principle, the upper bound of level IIb should reach the lateral skull base during delineation of the cervical CTV for NPC. To protect the parotid glands, however, individualized reduction of the upper bound of level IIb is recommended for patients who meet certain criteria.


2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Jan Heřman ◽  
Zuzana Sedláčková ◽  
Tomáš Fürst ◽  
Jaromír Vachutka ◽  
Richard Salzman ◽  
...  

Aim. To evaluate the prognostic value of ultrasound and shear-wave elastography (SWE) in diagnosing malignant cervical lymph nodes. Methods. A total of 99 patients with enlarged lymph nodes (99 lymph nodes presenting as a neck mass) were examined clinically with conventional ultrasound including Doppler examination and shear-wave elastography. The results of the examinations were compared with the final diagnosis. Results. There were 43 benign and 56 malignant lymph nodes in our cohort. Age and sex were significant predictors of malignancy. The standard ultrasound parameters—node size, long/short axis ratio, hilum, vascularization, and the presence of microcalcifications—were also statistically significant. Lymph node volume combined with age showed the best predictive power. The maximum stiffness found on SWE was also a significant predictor of malignancy. The combination of epidemiologic, classic ultrasound, and elastographic parameters yielded the highest sensitivity and specificity in the prediction of malignancy; however, the additional impact of elastographic parameters was low. Conclusion. A combination of epidemiologic and classic ultrasound parameters can discriminate between malignant and benign lymph nodes with satisfactory sensitivity and specificity. Examining the stiffness of lymph nodes by means of SWE does not add much new predictive power.


2018 ◽  
Author(s):  
David Emilio Barajas-Galindo ◽  
Luna Florencio-Ojeda ◽  
Maria Sevillano-Jimenez ◽  
Tomas Martin-Hernandez

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