Activity of Birinapant, a SMAC Mimetic Compound, Alone or in Combination in NSCLCs With Different Mutations

Frontiers in Oncology ◽

10.3389/fonc.2020.532292 ◽

2020 ◽

Vol 10 ◽

Author(s):

Marika Colombo ◽

Mirko Marabese ◽

Giulia Vargiu ◽

Massimo Broggini ◽

Elisa Caiola

Keyword(s):

Smac Mimetic ◽

Smac Mimetic Compound ◽

Mimetic Compound

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Blocking NF-κB and Akt by Hsp90 inhibition sensitizes Smac mimetic compound 3-induced extrinsic apoptosis pathway and results in synergistic cancer cell death

APOPTOSIS ◽

10.1007/s10495-010-0542-4 ◽

2010 ◽

Vol 16 (1) ◽

pp. 45-54 ◽

Author(s):

Lang Bai ◽

Shanling Xu ◽

Wenshu Chen ◽

Zi Li ◽

Xia Wang ◽

...

Keyword(s):

Cancer Cell ◽

Hsp90 Inhibition ◽

Apoptosis Pathway ◽

Cancer Cell Death ◽

Smac Mimetic ◽

Extrinsic Apoptosis ◽

Smac Mimetic Compound ◽

Mimetic Compound

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Attenuating Smac mimetic compound 3-induced NF-ÎºB activation by luteolin leads to synergistic cytotoxicity in cancer cells

Journal of Cellular Biochemistry ◽

10.1002/jcb.22346 ◽

2009 ◽

Vol 108 (5) ◽

pp. 1125-1131 ◽

Author(s):

Lang Bai ◽

Wenjie Chen ◽

Xia Wang ◽

Wei Ju ◽

Shanling Xu ◽

...

Keyword(s):

Cancer Cells ◽

Synergistic Cytotoxicity ◽

Smac Mimetic ◽

Smac Mimetic Compound ◽

Mimetic Compound

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Smac mimetic compound LCL161 sensitizes esophageal carcinoma cells to radiotherapy by inhibiting the expression of inhibitor of apoptosis protein

Tumor Biology ◽

10.1007/s13277-013-1338-2 ◽

2013 ◽

Vol 35 (3) ◽

pp. 2565-2574 ◽

Author(s):

Qin Qin ◽

Yun Zuo ◽

Xi Yang ◽

Jing Lu ◽

Liangliang Zhan ◽

...

Keyword(s):

Esophageal Carcinoma ◽

Carcinoma Cells ◽

Inhibitor Of Apoptosis ◽

Inhibitor Of Apoptosis Protein ◽

Apoptosis Protein ◽

Smac Mimetic ◽

Smac Mimetic Compound ◽

Mimetic Compound

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Cytotoxic effects of SMAC-mimetic compound LCL161 in head and neck cancer cell lines

Clinical Oral Investigations ◽

10.1007/s00784-016-1741-3 ◽

2016 ◽

Vol 20 (9) ◽

pp. 2325-2332 ◽

Author(s):

Roman C. Brands ◽

Franziska Herbst ◽

Stefan Hartmann ◽

Axel Seher ◽

Christian Linz ◽

...

Keyword(s):

Head And Neck Cancer ◽

Head And Neck ◽

Cancer Cell ◽

Neck Cancer ◽

Cancer Cell Lines ◽

Cytotoxic Effects ◽

Smac Mimetic ◽

Smac Mimetic Compound ◽

Mimetic Compound

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Radiosensitization of Head and Neck Squamous Cell Carcinoma by a SMAC-Mimetic Compound, SM-164, Requires Activation of Caspases

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-10-0643 ◽

2011 ◽

Vol 10 (4) ◽

pp. 658-669 ◽

Author(s):

Jie Yang ◽

Donna McEachern ◽

Wenyan Li ◽

Mary A. Davis ◽

Hua Li ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Neck Squamous Cell Carcinoma ◽

Smac Mimetic ◽

Smac Mimetic Compound ◽

Mimetic Compound

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Down-regulation of c-FLIP Enhances Death of Cancer Cells by Smac Mimetic Compound

Cancer Research ◽

10.1158/0008-5472.can-09-1794 ◽

2009 ◽

Vol 69 (19) ◽

pp. 7729-7738 ◽

Author(s):

Herman H. Cheung ◽

Douglas J. Mahoney ◽

Eric C. LaCasse ◽

Robert G. Korneluk

Keyword(s):

Cancer Cells ◽

Down Regulation ◽

Smac Mimetic ◽

Smac Mimetic Compound ◽

Mimetic Compound

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Smac-mimetic compound SM-164 induces radiosensitization in breast cancer cells through activation of caspases and induction of apoptosis

Breast Cancer Research and Treatment ◽

10.1007/s10549-011-1752-3 ◽

2011 ◽

Vol 133 (1) ◽

pp. 189-199 ◽

Author(s):

Dong Yang ◽

Yongchao Zhao ◽

Amy Y. Li ◽

Shaomeng Wang ◽

Gongxian Wang ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Breast Cancer Cells ◽

Smac Mimetic ◽

Induction Of Apoptosis ◽

Smac Mimetic Compound ◽

Mimetic Compound

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Faculty Opinions recommendation of Oncolytic virus synergizes with Smac mimetic compounds to induce rhabdomyosarcoma cell death in a syngeneic murine model.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727107848.793530875 ◽

2017 ◽

Author(s):

Kristiina Vuori ◽

Darren 'Ben' Finlay

Keyword(s):

Murine Model ◽

Oncolytic Virus ◽

Rhabdomyosarcoma Cell ◽

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Smac Mimetic APG-1387 Has Synergistic Effect with anti-PD1 Antibody via Increasing NK Cells Recruitment by Inducing Multiple Cytokines from Tumor Cells

SSRN Electronic Journal ◽

10.2139/ssrn.3388808 ◽

2019 ◽

Author(s):

Wentao Pan ◽

Qiuyun Luo ◽

Douglas D. Fang ◽

Guangfeng Wang ◽

Mude Shi ◽

...

Keyword(s):

Synergistic Effect ◽

Nk Cells ◽

Tumor Cells ◽

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Smac Mimetic Bypasses Apoptosis Resistance in FADD- or Caspase-8-Deficient Cells by Priming for Tumor Necrosis Factor α-Induced Necroptosis

Neoplasia ◽

10.1593/neo.11610 ◽

2011 ◽

Vol 13 (10) ◽

pp. 971-IN29 ◽

Author(s):

Bram Laukens ◽

Claudia Jennewein ◽

Barbara Schenk ◽

Nele Vanlangenakker ◽

Alexander Schier ◽

...

Keyword(s):

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Tumor Necrosis Factor Α ◽

Caspase 8 ◽

Apoptosis Resistance ◽

Smac Mimetic ◽

Factor Α ◽

Necrosis Factor

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