scholarly journals Transcutaneous Vagus Nerve Stimulation Does Not Affect Verbal Memory Performance in Healthy Volunteers

2020 ◽  
Vol 11 ◽  
Author(s):  
Ann Mertens ◽  
Lien Naert ◽  
Marijke Miatton ◽  
Tasha Poppa ◽  
Evelien Carrette ◽  
...  
Keyword(s):  
Vagus Nerve ◽  
Healthy Volunteers ◽  
Nerve Stimulation ◽  
Verbal Memory ◽  
Vagus Nerve Stimulation ◽  
Memory Performance ◽  
Transcutaneous Vagus Nerve Stimulation

scholarly journals The Potential of Invasive and Non-Invasive Vagus Nerve Stimulation To Improve Verbal Memory Performance in Epilepsy Patients

2021 ◽  
Author(s):  
Ann Mertens ◽  
Stefanie Gadeyne ◽  
Emma Lescrauwaet ◽  
Evelien Carrette ◽  
Alfred Meurs ◽  
...  
Keyword(s):  
Word Recognition ◽  
Recognition Memory ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Verbal Memory ◽  
Vagus Nerve Stimulation ◽  
Memory Performance ◽  
Non Invasive ◽  
Immediate Recall ◽  
Delayed Recognition

Abstract Introduction: It has been demonstrated that acute vagus nerve stimulation (VNS) improves word recognition memory in epilepsy patients. Transcutaneous auricular vagus nerve stimulation (taVNS) has gained interest as a non-invasive alternative to improve cognition. In this prospective randomized cross-over study, we investigated the effect of both invasive VNS and taVNS on verbal memory performance in 15 drug-resistant epilepsy patients. Methods All patients conducted a word recognition memory paradigm in 3 conditions: VNS ON, VNS OFF and taVNS. For each condition, patients memorized 21 highlighted words from text paragraphs. Afterwards, the intervention was delivered for 30 s. Immediate recall and delayed recognition scores were obtained for each condition. This memory paradigm was repeated after 6 weeks of VNS therapy in 2 conditions: VNS ON and VNS OFF. Results Acute VNS and taVNS did not improve verbal memory performance. Immediate recall and delayed recognition scores were significantly improved after 6 weeks of VNS treatment irrespective of the acute intervention. Conclusion The previously described positive effects of invasive VNS on verbal memory performance could not be replicated with invasive VNS and taVNS. An improved verbal memory performance was seen after 6 weeks of VNS treatment, suggesting that longer and more repetitive stimulation of the vagal pathway is required to modulate verbal memory performance.

scholarly journals Modulation of memory performance and brain activity by non-invasive auricular transcutaneous vagus nerve stimulation in a mouse model of intellectual disability disorder

2021 ◽  
Vol 14 (6) ◽  
pp. 1593-1594
Author(s):  
Cecilia Brambilla Pisoni ◽  
Emma Muñoz Moreno ◽  
Anna Vázquez Oliver ◽  
Rafael Maldonado Lopez ◽  
Antoni Ivorra Cano ◽  
...  
Keyword(s):  
Intellectual Disability ◽  
Mouse Model ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Brain Activity ◽  
Memory Performance ◽  
Non Invasive ◽  
Transcutaneous Vagus Nerve Stimulation

scholarly journals Transcutaneous vagus nerve stimulation increases locus coeruleus function and memory performance in older individuals

2020 ◽  
Vol 16 (S6) ◽  
Author(s):  
Heidi I.L. Jacobs ◽  
Nikos Priovoulos ◽  
Joost M Riphagen ◽  
Benedikt A. Poser ◽  
Vitaly Napadow ◽  
...  
Keyword(s):  
Vagus Nerve ◽  
Locus Coeruleus ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Memory Performance ◽  
Older Individuals ◽  
Transcutaneous Vagus Nerve Stimulation

Effect of Transcutaneous Vagus Nerve Stimulation in Dysphagia After Lateral Medullary Infarction: A Case Report

2019 ◽  
Vol 28 (4) ◽  
pp. 1381-1387
Author(s):  
Ying Yuan ◽  
Jie Wang ◽  
Dongyu Wu ◽  
Dahua Zhang ◽  
Weiqun Song
Keyword(s):  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Rating Scale ◽  
Tube Feeding ◽  
Nasogastric Feeding ◽  
Lateral Medullary Infarction ◽  
Severe Dysphagia ◽  
Transcutaneous Vagus Nerve Stimulation ◽  
Medullary Infarction

Purpose Severe dysphagia with weak pharyngeal peristalsis after dorsal lateral medullary infarction (LMI) requires long-term tube feeding. However, no study is currently available on therapeutic effectiveness in severe dysphagia caused by nuclear damage of vagus nerve after dorsal LMI. The purpose of the present investigation was to explore the potential of transcutaneous vagus nerve stimulation (tVNS) to improve severe dysphagia with weak pharyngeal peristalsis after dorsal LMI. Method We assessed the efficacy of 6-week tVNS in a 28-year-old woman presented with persisting severe dysphagia after dorsal LMI who had been on nasogastric feeding for 6 months. tVNS was applied for 20 min twice a day, 5 days a week, for 6 weeks. The outcome measures included saliva spitted, Swallow Function Scoring System, Functional Oral Intake Scale, Clinical Assessment of Dysphagia With Wallenberg Syndrome, Yale Pharyngeal Residue Severity Rating Scale, and upper esophagus X-ray examination. Results After tVNS, the patient was advanced to a full oral diet without head rotation or spitting. No saliva residue was found in the valleculae and pyriform sinuses. Contrast medium freely passed through the upper esophageal sphincter. Conclusion Our findings suggest that tVNS might provide a useful means for recovery of severe dysphagia with weak pharyngeal peristalsis after dorsal LMI. Supplemental Material https://doi.org/10.23641/asha.9755438

scholarly journals Evidence of activation of vagal afferents by non-invasive vagus nerve stimulation: An electrophysiological study in healthy volunteers

Cephalalgia ◽  
2017 ◽  
Vol 37 (13) ◽  
pp. 1285-1293 ◽  
Author(s):  
Romain Nonis ◽  
Kevin D’Ostilio ◽  
Jean Schoenen ◽  
Delphine Magis
Keyword(s):  
Vagus Nerve ◽  
Healthy Volunteers ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Electrophysiological Study ◽  
Vagal Afferents ◽  
Response Analysis ◽  
Bipolar Electrode ◽  
Non Invasive ◽  
Vagal Afferent

Background Benefits of cervical non-invasive vagus nerve stimulation (nVNS) devices have been shown in episodic cluster headache and preliminarily suggested in migraine, but direct evidence of vagus nerve activation using such devices is lacking. Vagal somatosensory evoked potentials (vSEPs) associated with vagal afferent activation have been reported for invasive vagus nerve stimulation (iVNS) and non-invasive auricular vagal stimulation. Here, we aimed to show and characterise vSEPs for cervical nVNS. Methods vSEPs were recorded for 12 healthy volunteers who received nVNS over the cervical vagus nerve, bipolar electrode/DS7A stimulation over the inner tragus, and nVNS over the sternocleidomastoid (SCM) muscle. We measured peak-to-peak amplitudes (P1-N1), wave latencies, and N1 area under the curve. Results P1-N1 vSEPs were observed for cervical nVNS (11/12) and auricular stimulation (9/12), with latencies similar to those described previously, whereas SCM stimulation revealed only a muscle artefact with a much longer latency. A dose-response analysis showed that cervical nVNS elicited a clear vSEP response in more than 80% of the participants using an intensity of 15 V. Conclusion Cervical nVNS can activate vagal afferent fibres, as evidenced by the recording of far-field vSEPs similar to those seen with iVNS and non-invasive auricular stimulation.

scholarly journals Transcutaneous Vagus Nerve Stimulation is Associated with Lower Mechanical Ventilation and Mortality in COVID-19 Patients

2021 ◽  
Vol 6 (2) ◽  
Author(s):  
Nemechek P ◽  
Antonelli G ◽  
Braida A
Keyword(s):  
Mechanical Ventilation ◽  
Respiratory Failure ◽  
Vagus Nerve ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Safety And Efficacy ◽  
Transcutaneous Vagus Nerve Stimulation

Objective: Evaluate the safety and efficacy of transcutaneous vagus nerve stimulation in preventing respiratory failure and improving survival in hospitalized COVID-19 patients.

Sign in / Sign up

Export Citation Format

Share Document