scholarly journals Predictors of Post-stroke Cognition Among Geriatric Patients: The Role of Demographics, Pre-stroke Cognition, and Trajectories of Depression

2021 ◽  
Vol 12 ◽  
Author(s):  
Christiana Kang

Stroke is a prevalent disease among geriatric population, which tends to deteriorate cognitive ability and mental health. In such context, cognitive impairment and geriatric depression generate mutually deteriorating impacts on each other. Using the Health and Retirement Study, this study examined depression and cognition before, immediately after, and 2 years after the onset of stroke. Through latent growth mixture modeling, four different trajectories of depression were identified: resilience, recovery, emergent depression, and chronicity. We used demographics including gender, age, race, and ethnicity, activity of daily life, baseline cognition, and trajectories of depression to predict cognitive ability 2 years after the stroke. Both aforementioned demographic factors and pre-stroke cognition were predictive of post-stroke cognition, but the inclusion of depression trajectories further improved the predictive ability. Emergent depression and chronicity were two significant predictors of worse post-stroke cognition. This study showed the importance of considering a more specific trajectotrial interrelationship between depression and cognition in geriatric stroke patients.

2019 ◽  
pp. 60-100
Author(s):  
David M. Day ◽  
Margit Wiesner

Criminal offenders compose a heterogeneous population. Criminal trajectory research aims to capture this heterogeneity in terms of the frequency or severity of offending. This chapter describes the concept a criminal trajectory and the statistical technique used to derive trajectories from longitudinal data. Both the semiparametric group-based trajectory modeling (SGBTM) and latent growth mixture modeling (GMM) approaches are described in nontechnical terms, and the differences between them are noted. Despite some similarities, these approaches are also distinguished from conventional growth curve modeling. Guidelines and factors to consider in building and testing trajectory models are discussed. Last, extensions of SGBTM and GMM are presented.


2001 ◽  
Vol 20 (2) ◽  
pp. 127-135 ◽  
Author(s):  
Craig R. Colder ◽  
Paras Mehta ◽  
Kevin Balanda ◽  
Richard T. Campbell ◽  
Kathryn Mayhew ◽  
...  

2017 ◽  
Vol 5 (5) ◽  
pp. 843-850 ◽  
Author(s):  
Matteo Malgaroli ◽  
Isaac R. Galatzer-Levy ◽  
George A. Bonanno

Divorce is a common stressful event associated with both increased rates of depression and mortality. Given evidence of significant individual differences in depression following major life stressors, we examined if heterogeneous depression responses confer differential risk for mortality. Data from a population-based longitudinal study was utilized to identify individuals who experienced divorce ( n = 559). Prospective trajectories of depression severity from before to after divorce were identified using latent growth mixture modeling, and rates of mortality between trajectories were compared as a distal outcome. Four trajectories demonstrated strongest model fit: resilience (67%), emergent depression (10%), chronic pre- to postdivorce depression (12%), and decreasing depression (11%). Mortality base rate was 9.7% by 6 years postevent, and depression that emerged due to divorce was associated with significantly greater mortality risk compared to resilient (odds ratio [OR] = 2.46; 95% confidence interval [CI] = [1.05, 5.81]) and to married individuals, whereas chronic depression was not associated with greater risk.


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