scholarly journals Late-Onset OCD as a Potential Harbinger of Dementia With Lewy Bodies: A Report of Two Cases

2020 ◽  
Vol 11 ◽  
Author(s):  
Solène Frileux ◽  
Bruno Millet ◽  
Philippe Fossati
Keyword(s):  
Dementia With Lewy Bodies ◽  
Late Onset ◽  
Lewy Bodies

Ventilatory Response to Hypercapnia Predicts Dementia with Lewy Bodies in Late-Onset Major Depressive Disorder

2016 ◽  
Vol 50 (3) ◽  
pp. 751-758 ◽  
Author(s):  
Sho Takahashi ◽  
Katsuyoshi Mizukami ◽  
Tetsuaki Arai ◽  
Ryoko Ogawa ◽  
Norihiro Kikuchi ◽  
...  
Keyword(s):  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Dementia With Lewy Bodies ◽  
Late Onset ◽  
Ventilatory Response ◽  
Lewy Bodies ◽  
Major Depressive

GRN Thr272fs Clinical Heterogeneity: A Case with Atypical Late Onset Presenting with a Dementia with Lewy Bodies Phenotype

2013 ◽  
Vol 35 (4) ◽  
pp. 669-674 ◽  
Author(s):  
Beatrice Arosio ◽  
Carlo Abbate ◽  
Daniela Galimberti ◽  
Paolo Dionigi Rossi ◽  
Silvia Inglese ◽  
...  
Keyword(s):  
Dementia With Lewy Bodies ◽  
Late Onset ◽  
Lewy Bodies ◽  
Clinical Heterogeneity

scholarly journals P1-053: Genome-wide analysis of DNA methylation differentiates late-onset Alzheimer's disease from dementia with Lewy bodies

2013 ◽  
Vol 9 ◽  
pp. P171-P172
Author(s):  
Crystal Humphries ◽  
Patrice L. Whitehead ◽  
Deborah Mash ◽  
Gary Beecham ◽  
Margaret Pericak-Vance ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Dna Methylation ◽  
Dementia With Lewy Bodies ◽  
Late Onset ◽  
Lewy Bodies ◽  
Genome Wide Analysis ◽  
Genome Wide

scholarly journals Filamentous nerve cell inclusions in neurodegenerative diseases: tauopathies and alpha-synucleinopathies

1999 ◽  
Vol 354 (1386) ◽  
pp. 1101-1118 ◽  
Author(s):  
Michel Goedert
Keyword(s):  
Neurodegenerative Diseases ◽  
Dementia With Lewy Bodies ◽  
Late Onset ◽  
Lewy Bodies ◽  
Corticobasal Degeneration ◽  
New Work ◽  
Missense Mutations ◽  
Protein Tau ◽  
Frontotemporal Dementias ◽  
Filamentous Inclusions

Alzheimer'sdisease and Parkinson'sdisease are the most common neurodegenerative diseases. They are characterized by the degeneration of selected populations of nerve cells that develop filamentous inclusions before degeneration. The neuronal inclusions of Alzheimer'sdisease are made of the microtubule–associated protein tau, in a hyperphosphorylated state. Recent work has shown that the filamentous inclusions of Parkinson'sdisease are made of the protein α–synuclein and that rare, familial forms of Parkinson'sdisease are caused by missense mutations in the α–synuclein gene. Besides Parkinson'sdisease, the filamentous inclusions of two additional neurodegenerative diseases, namely dementia with Lewy bodies and multiple system atrophy, have also been found to be made of α–synuclein. Abundant filamentous tau inclusions are not limited to Alzheimer'sdisease. They are the defining neuropathological characteristic of frontotemporal dementias such as Pick'sdisease, and of progressive supranuclear palsy and corticobasal degeneration. The recent discovery of mutations in the tau gene in familial forms of frontotemporal dementia has provided a direct link between tau dysfunction and dementing disease. The new work has established that tauopathies and α–synucleinopathies account for most late–onset neurodegenerative diseases in man. The formation of intracellular filamentous inclusions might be the gain of toxic function that leads to the demise of affected brain cells.

Differences in glucose metabolism between dementia with Lewy bodies and dementia associated with Parkinson's disease

2005 ◽  
Vol 32 (S 4) ◽  
Author(s):  
P Häussermann ◽  
A.O Ceballos-Baumann ◽  
H Förstl ◽  
R Feurer ◽  
B Conrad ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Glucose Metabolism ◽  
Dementia With Lewy Bodies ◽  
Lewy Bodies

Dementia with Lewy bodies

2018 ◽  
pp. 11-21
Author(s):  
O. S. Levin ◽  
E. E. Vasenina ◽  
A. Sh. Chimagomedova ◽  
N. G. Dudchenko
Keyword(s):  
Parkinson’S Disease ◽  
Dementia With Lewy Bodies ◽  
Cholinesterase Inhibitors ◽  
Lewy Bodies ◽  
Diagnosis And Treatment ◽  
Modern Concept ◽  
Historical Aspect ◽  
Neurodegenerative Process ◽  
Icd 10

Te lecture presents modern concept of the symptoms, diagnosis and treatment of dementia with Lewy bodies (DLB), which accounts for about 10% of cases of dementia. Te nosological status of DLB and the problem of ratio of DLB and Parkinson’s disease which, apparently, represent two phenotypic variants of one neurodegenerative process («diseases with Lewy bodies») are considered in historical aspect. Approaches to the diagnosis and coding of DLB in accordance with ICD-10 are proposed. Te role of cholinesterase inhibitors, antipsychotics, levodopa, rasagiline and other drugs in the treatment of patients with DLB is аnalyzed.

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