scholarly journals Effect of Nigella sativa (seed and oil) on the bacteriological quality of soft white cheese

2011 ◽  
Vol 25 (1) ◽  
pp. 21-27 ◽  
Author(s):  
H. S. Alnaemi ◽  
S. D. Alsawaf
Dose-Response ◽  
2021 ◽  
Vol 19 (2) ◽  
pp. 155932582110136
Author(s):  
Mohamed F. Radwan ◽  
Mohamed A. El-Moselhy ◽  
Walied M. Alarif ◽  
Mohamed Orif ◽  
Nabil K. Alruwaili ◽  
...  

To improve the water solubility of thymoquinone (TQ), a major constituent of Nigella sativa seed oil, a TQ-loaded self-nanoemulsifying drug delivery system (SNEDDS) was prepared. The SNEDDS formulation was optimized using almond oil (AO) (Oil; X1), tween 80 (surfactant; X2) and polyethylene glycol 200 (PEG 200) (cosurfactant; X3) compounds as independent variables. The results showed that the globule size ranged from 65 to 320 nm. In addition, a strong agreement was reached between the system estimation and the experimental values of globule size. To evaluate the gastroprotective effect of optimized TQ-loaded SNEDDS against indomethacin (Indo.)-induced gastric ulcers in comparison with non-emulsified TQ, the ulcer index and histopathological changes were estimated. Optimized TQ-loaded SNEDDS showed improved gastroprotective activity against Indo.-induced ulcers relative to the non-emulsified TQ. In addition, the gastroprotective index was improved by 2-fold in TQ-loaded SNEDDS as compared to non-emulsified TQ. This is attributed to the strong antioxidant and the cytoprotective activities of the TQ. These results demonstrate enhancement of the efficacy of TQ through the optimized SNEDDS.


2017 ◽  
Vol 11 ◽  
pp. 117863021773553 ◽  
Author(s):  
Joab Odhiambo Okullo ◽  
Wilkister Nyaora Moturi ◽  
George Morara Ogendi

2015 ◽  
Vol 10 (53) ◽  
pp. 4844-4849 ◽  
Author(s):  
Benmerine BENGARNIA ◽  
Miloud HADADJI ◽  
Mohammed RAMDANI ◽  
Mebrouk KIHAL

2018 ◽  
Vol 7 (2) ◽  
Author(s):  
Amnah M.A. Alsuhaibani

In this study, the gross composition and mineral content of Nigella sativa seed powder (NSP) and fatty acid composition of Nigella sativa oil (NSO) were investigated. The ability of NSP, extract (NSE) and NSO in reducing the effects of cisplatin-induced renal toxicity in Sprague-Dawley rats were examined. The obtained results showed that NSP contains high amounts of carbohydrates, protein, and fiber while NSO has higher amounts of linoleicacid, oleic acid, and myristic acid. Rats treated with NSP, NSO, and NSE exhibitedreducedserum levels of urea, creatinine, and potassium, and a significant increase of Na, Na/K, vitamin D, nutritional markers, and antioxidant enzymes compared to the cisplatin-induced renal toxicity group receiving no Nigella sativa seed treatment. This study determined that all powder, oil, and extracts of N. sativa contain potent bioactive components that may aid in treatment against cisplatininduced renal toxicity in rats.


Food Control ◽  
2014 ◽  
Vol 41 ◽  
pp. 147-150 ◽  
Author(s):  
R. Abd-Elaleem ◽  
W.M.K. Bakr ◽  
W.A. Hazzah ◽  
O. Nasreldin

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