scholarly journals Oxytocin Receptor Gene Polymorphism in Lactating Dogs

Animals ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 3099
Author(s):  
Asahi Ogi ◽  
Valentina Naef ◽  
Filippo Maria Santorelli ◽  
Chiara Mariti ◽  
Angelo Gazzano
Keyword(s):  
Social Behavior ◽  
Maternal Behavior ◽  
Maternal Care ◽  
Receptor Gene ◽  
Oxytocin Receptor ◽  
Single Nucleotide ◽  
Oxytocin Receptor Gene ◽  
Receptor Gene Polymorphism ◽  
Polymorphic Variants ◽  
Evolution Of Mammals

Genetic variations in the oxytocinergic system, known to regulate social behavior throughout the evolution of mammals, are believed to account for differences in mammalian social behavior. Particularly, polymorphic variants of the oxytocin receptor (OXTR) gene have been associated with behavioral variations in both humans and dogs. In this study, we offered evidence of the correlation between levels of salivary oxytocin (sOXT), maternal behavior and a single-nucleotide gene variant in OXTR (rs8679684) in nineteen lactating Labrador Retriever dogs. Carriers of at least one copy of the minor A allele showed higher levels of sOXT and maternal care in comparison with the homozygous T allele carriers. Considering the relevance of mother care in newborn development, these findings could help us to better understand the possible impact of variants in the OXTR gene in selecting dams.

scholarly journals Oxytocin Receptor Gene Polymorphisms Are Associated with Human Directed Social Behavior in Dogs (Canis familiaris)

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e83993 ◽  
Author(s):  
Anna Kis ◽  
Melinda Bence ◽  
Gabriella Lakatos ◽  
Enikő Pergel ◽  
Borbála Turcsán ◽  
...  
Keyword(s):  
Social Behavior ◽  
Gene Polymorphisms ◽  
Receptor Gene ◽  
Canis Familiaris ◽  
Oxytocin Receptor ◽  
Oxytocin Receptor Gene ◽  
Receptor Gene Polymorphisms

scholarly journals Polychlorinated biphenyl exposure alters oxytocin receptor gene expression and maternal behavior in rat model

2015 ◽  
Vol 3 (1) ◽  
pp. e979681 ◽  
Author(s):  
E Nicole Dover ◽  
David E Mankin ◽  
Howard C Cromwell ◽  
Vipaporn Phuntumart ◽  
Lee A Meserve
Keyword(s):  
Gene Expression ◽  
Rat Model ◽  
Maternal Behavior ◽  
Polychlorinated Biphenyl ◽  
Receptor Gene ◽  
Oxytocin Receptor ◽  
Oxytocin Receptor Gene ◽  
Receptor Gene Expression

scholarly journals Variation in the Oxytocin Receptor Gene Is Associated with Pair-Bonding and Social Behavior

2012 ◽  
Vol 71 (5) ◽  
pp. 419-426 ◽  
Author(s):  
Hasse Walum ◽  
Paul Lichtenstein ◽  
Jenae M. Neiderhiser ◽  
David Reiss ◽  
Jody M. Ganiban ◽  
...  
Keyword(s):  
Social Behavior ◽  
Receptor Gene ◽  
Oxytocin Receptor ◽  
Pair Bonding ◽  
Oxytocin Receptor Gene

scholarly journals The relation between Oxytocin Receptor Gene polymorphisms, adult attachment and Instagram sociability: an exploratory analysis

2020 ◽  
Author(s):  
Alessandro Carollo ◽  
Andrea Bonassi ◽  
Ilaria Cataldo ◽  
Giulio Gabrieli ◽  
Moses Tandiono ◽  
...  
Keyword(s):  
Social Behavior ◽  
Adult Attachment ◽  
Behavioral Genetics ◽  
Receptor Gene ◽  
Oxytocin Receptor ◽  
Oxytocin Receptor Gene ◽  
Gene Environment ◽  
Receptor Gene Polymorphisms ◽  
Oxtr Rs53576 ◽  
Desirability Index

So far literature considered the association between environmental factors (i.e. involved in adult relationships) and genetic vulnerability on Oxytocin Receptor Gene (OXTR) in the comprehension of social behavior. Although an extensive knowledge on in-person social interactions has been obtained, little is known about online social behavior. A gene-environment perspective is adopted to examine how OXTR and adult attachment moderate Instagram behavior. The Experience in Close Relationships-Revised (ECR-R) questionnaire was used to collect participants' (N = 57, 16 males) attachment with their partners. The genetic factors within the regions OXTR rs53576 (A/A homozygotes vs. G-carriers) and rs2254298 (G/G homozygotes vs. A-carriers) were assessed. Number of posts, followed people ("followings") and followers were obtained from Instagram, and the Social Desirability Index was calculated as the ratio of followers to followings. Interaction effects between OXTR groups and ECR-R scores on the number of posts and SDI were hypothesised. Results showed an effect of rs53576 on the number of Instagram followings. Specifically, A/A homozygotes had more followings than G-carriers independently of the quality of the relationship with their partner. These preliminary results are discussed in light of the debate of behavioral genetics and offer insights into future investigations on social media behavior.

The interaction between oxytocin receptor gene methylation and maternal behavior on children's early theory of mind abilities

2019 ◽  
Vol 32 (2) ◽  
pp. 511-519
Author(s):  
Anna L. MacKinnon ◽  
Nancy Feeley ◽  
Ian Gold ◽  
Barbara Hayton ◽  
Leonora King ◽  
...  
Keyword(s):  
Theory Of Mind ◽  
Maternal Behavior ◽  
Maternal Education ◽  
Negative Impact ◽  
Receptor Gene ◽  
Community Sample ◽  
Mental States ◽  
Oxytocin Receptor ◽  
Early Theory ◽  
Oxytocin Receptor Gene

AbstractTheory of mind, the ability to represent the mental states of others, is an important social cognitive process, which contributes to the development of social competence. Recent research suggests that interactions between gene and environmental factors, such as oxytocin receptor gene (OXTR) polymorphisms and maternal parenting behavior, may underlie individual differences in children's theory of mind. However, the potential influence of DNA methylation of OXTR remains unclear. The current study investigated the roles of OXTR methylation, maternal behavior, and their statistical interaction on toddlers’ early emerging theory of mind abilities. Participants included a community sample of 189 dyads of mothers and their 2- to 3-year-old children, whose salivary DNA was analyzed. Results indicated that more maternal structuring behavior was associated with better performance, on a battery of three theory of mind tasks, while higher OXTR methylation within exon 3 was associated with poorer performance. A significant interaction also emerged, such that OXTR methylation was related to theory of mind among children whose mothers displayed less structuring, when controlling for children's age, sex, ethnicity, number of child-aged siblings, verbal ability, and maternal education. Maternal structuring behavior may buffer the potential negative impact of hypermethylation on OXTR gene expression and function.

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