scholarly journals Polychlorinated biphenyl exposure alters oxytocin receptor gene expression and maternal behavior in rat model

2015 ◽  
Vol 3 (1) ◽  
pp. e979681 ◽  
Author(s):  
E Nicole Dover ◽  
David E Mankin ◽  
Howard C Cromwell ◽  
Vipaporn Phuntumart ◽  
Lee A Meserve
Keyword(s):  
Gene Expression ◽  
Rat Model ◽  
Maternal Behavior ◽  
Polychlorinated Biphenyl ◽  
Receptor Gene ◽  
Oxytocin Receptor ◽  
Oxytocin Receptor Gene ◽  
Receptor Gene Expression

The role of the endometrial oxytocin receptor in determining the length of the sterile oestrous cycle and ensuring maintenance of luteal function in early pregnancy in ruminants

1994 ◽  
Vol 344 (1309) ◽  
pp. 291-304 ◽  
Keyword(s):  
Gene Expression ◽  
Molecular Mechanisms ◽  
Transmembrane Domain ◽  
Receptor Gene ◽  
Oxytocin Receptor ◽  
Oestrous Cycle ◽  
High Rate ◽  
Endocrine Function ◽  
Oxytocin Receptor Gene ◽  
Receptor Gene Expression

The oxytocin receptor, a seven transmembrane domain, G protein-linked receptor molecule, plays a central role in determining the endocrine function of the ruminant uterine endometrium. During non- pregnant cycles the control of this molecule by circulating steroid hormones leads to regression of the corpora lutea. The kinetics of the mechanisms involved determine the time at which luteolysis occurs, and therefore the length of the oestrous cycle. In pregnancy, secretions of the trophoblast block endometrial oxytocin receptor gene expression and lead to luteal maintenance. An understanding of the molecular mechanisms involved in the steroidal control of oxytocin receptor gene expression will provide an explanation for the relative constancy of oestrous cycle lengths in non-pregnant animals. Unravelling the way in which trophoblast products block expression of the oxytocin receptor gene will lead to a better understanding of the reasons for the high rate of embryonic loss in domestic ruminants.

scholarly journals Oxytocin and Oxytocin Receptor Gene Expression in the Reproductive Tract of the Pregnant Cow: Rescue of Luteal Oxytocin Production at Term1

1995 ◽  
Vol 53 (3) ◽  
pp. 553-560 ◽  
Author(s):  
Richard Ivell ◽  
Werner Rust ◽  
Almuth Einspanier ◽  
Stefan Hartung ◽  
Michael Fields ◽  
...  
Keyword(s):  
Gene Expression ◽  
Reproductive Tract ◽  
Receptor Gene ◽  
Oxytocin Receptor ◽  
Oxytocin Receptor Gene ◽  
Receptor Gene Expression

Estrogen increases renal oxytocin receptor gene expression.

Endocrinology ◽  
1995 ◽  
Vol 136 (4) ◽  
pp. 1801-1804 ◽  
Author(s):  
N L Ostrowski ◽  
W S Young ◽  
S J Lolait
Keyword(s):  
Gene Expression ◽  
Receptor Gene ◽  
Oxytocin Receptor ◽  
Oxytocin Receptor Gene ◽  
Receptor Gene Expression

Reduced oxytocin receptor gene expression and binding sites in different brain regions in schizophrenia: A post-mortem study

2016 ◽  
Vol 177 (1-3) ◽  
pp. 59-66 ◽  
Author(s):  
Stefanie Uhrig ◽  
Natalie Hirth ◽  
Laura Broccoli ◽  
Martina von Wilmsdorff ◽  
Manfred Bauer ◽  
...  
Keyword(s):  
Gene Expression ◽  
Binding Sites ◽  
Receptor Gene ◽  
Brain Regions ◽  
Oxytocin Receptor ◽  
Post Mortem ◽  
Oxytocin Receptor Gene ◽  
Receptor Gene Expression

scholarly journals Identification of a GABPα/β Binding Site Involved in the Induction of Oxytocin Receptor Gene Expression in Human Breast Cells. Potentiation by c-Fos/c-Jun*

Endocrinology ◽  
1999 ◽  
Vol 140 (5) ◽  
pp. 2268-2279 ◽  
Author(s):  
Sarasija Hoare ◽  
John A. Copland ◽  
Thomas G. Wood ◽  
Yow-Jiun Jeng ◽  
Michael G. Izban ◽  
...  
Keyword(s):  
Gene Expression ◽  
Binding Site ◽  
Receptor Gene ◽  
Oxytocin Receptor ◽  
Human Breast ◽  
Oxytocin Receptor Gene ◽  
Breast Cells ◽  
Receptor Gene Expression
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