scholarly journals Genetic Algorithm Based Deep Learning Neural Network Structure and Hyperparameter Optimization

2021 ◽  
Vol 11 (2) ◽  
pp. 744
Author(s):  
Sanghyeop Lee ◽  
Junyeob Kim ◽  
Hyeon Kang ◽  
Do-Young Kang ◽  
Jangsik Park

Alzheimer’s disease is one of the major challenges of population ageing, and diagnosis and prediction of the disease through various biomarkers is the key. While the application of deep learning as imaging technologies has recently expanded across the medical industry, empirical design of these technologies is very difficult. The main reason for this problem is that the performance of the Convolutional Neural Networks (CNN) differ greatly depending on the statistical distribution of the input dataset. Different hyperparameters also greatly affect the convergence of the CNN models. With this amount of information, selecting appropriate parameters for the network structure has became a large research area. Genetic Algorithm (GA), is a very popular technique to automatically select a high-performance network architecture. In this paper, we show the possibility of optimising the network architecture using GA, where its search space includes both network structure configuration and hyperparameters. To verify the performance of our Algorithm, we used an amyloid brain image dataset that is used for Alzheimer’s disease diagnosis. As a result, our algorithm outperforms Genetic CNN by 11.73% on a given classification task.

Proceedings ◽  
2019 ◽  
Vol 21 (1) ◽  
pp. 28
Author(s):  
Alejandro Puente-Castro ◽  
Cristian Robert Munteanu ◽  
Enrique Fernandez-Blanco

Automatic detection of Alzheimer’s disease is a very active area of research. This is due to its usefulness in starting the protocol to stop the inevitable progression of this neurodegenerative disease. This paper proposes a system for the detection of the disease by means of Deep Learning techniques in magnetic resonance imaging (MRI). As a solution, a model of neuronal networks (ANN) and two sets of reference data for training are proposed. Finally, the goodness of this system is verified within the domain of the application.


Author(s):  
ChangZu Chen ◽  
Qi Wu ◽  
ZuoYong Li ◽  
Lei Xiao ◽  
Zhong Yi Hu

Aim and Objective: Fast and accurate diagnosis of Alzheimer's disease is very important for the care and further treatment of patients. Along with the development of deep learning, impressive progress has also been made in the automatic diagnosis of AD. Most existing studies on automatic diagnosis are concerned with a single base network, whose accuracy for disease diagnosis still needs to be improved. This study was undertaken to propose a method to improve the accuracy of automatic diagnosis of AD. Materials and Methods: MRI image data from the Alzheimer’s Disease Neuroimaging Initiative were used to train a deep learning model to achieve computer-aided diagnosis of Alzheimer's disease. The data consisted of 138 with AD, 280 with mild cognitive impairment, and 138 normal controls. Here, a new deeply-fused net is proposed, which combines several deep convolutional neural networks, thereby avoiding the error of a single base network and increasing the classification accuracy and generalization capacity. Results: Experiments show that when differentiating between patients with AD, mild cognitive impairment, and normal controls on a subset of the ADNI database without data leakage, the new architecture improves the accuracy by about 4 percentage points as compared to a single standard base network. Conclusion: This new approach exhibits better performance, but there is still much to be done before its clinical application. In the future, greater research effort will be devoted to improving the performance of the deeply-fused net.


IEEE Access ◽  
2019 ◽  
Vol 7 ◽  
pp. 63605-63618 ◽  
Author(s):  
Chiyu Feng ◽  
Ahmed Elazab ◽  
Peng Yang ◽  
Tianfu Wang ◽  
Feng Zhou ◽  
...  

2013 ◽  
Vol 9 ◽  
pp. P455-P456
Author(s):  
Piers Johnson ◽  
Petra Graham ◽  
Bill Wilson ◽  
Lance Macaulay ◽  
Paul Maruff ◽  
...  

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