scholarly journals Regenerative Healing of Chitosan Scaffold Impregnated with Simvastatin in Repairing Furcal Perforation

2021 ◽  
Vol 11 (19) ◽  
pp. 8992
Author(s):  
Ghaliah M. Alsawah ◽  
Manal Alsheddi ◽  
Ebtissam M. Al-Madi ◽  
Mohammad I. Al-Obaida
Keyword(s):  
Bone Regeneration ◽  
Root Canal ◽  
Mineral Trioxide Aggregate ◽  
Control Group ◽  
Tissue Formation ◽  
Glass Ionomer ◽  
Hard Tissue ◽  
Biological Responses ◽  
Resin Modified Glass Ionomer ◽  
White Mineral

This study aimed to evaluate the healing of furcation when repaired with Chitosan (CS) scaffold impregnated or not with Simvastatin (SIM) compared with CollaCote (CL) in goat premolar teeth. Root canal treatment was performed in 52 mandibular premolars followed by furcal perforation induction. The perforation was repaired with CL, CS, or CS with SIM after leaving it untreated for 4 weeks. White mineral trioxide aggregate was carried into the furcal site followed by a 2–3 mm resin-modified glass ionomer. The perforation was left untreated, and the access cavity was left open without coronal filling in the control group. The animals were sacrificed after one and three months. Block sections of the premolars were prepared and examined histologically to evaluate the inflammation and type of healing. Hard tissue formation was found in CL, CS, and CS/SIM groups in both periods. At one month, no significant differences were detected among the experimental groups, whereas at three months, CS without SIM showed significantly better performance compared to CL and CS/SIM groups (p = 0.040). Therefore, repairing furcal perforation with CS scaffolds shows desirable biological responses and healing characteristics in favor of bone regeneration at three months.

scholarly journals Pulpal Response to the Combined Use of Mineral Trioxide Aggregate and Iloprost for Direct Pulp Capping

2021 ◽  
Vol 11 (8) ◽  
pp. 3702
Author(s):  
AlAnoud Almeshari ◽  
Rita Khounganian ◽  
Wael Mahdi ◽  
Fahd Aljarbou ◽  
Shilpa Bhandi ◽  
...  
Keyword(s):  
Mineral Trioxide Aggregate ◽  
Control Group ◽  
Dentinal Tubule ◽  
Glass Ionomer ◽  
Hard Tissue ◽  
Inflammatory Reactions ◽  
Pulp Capping ◽  
Tissue Degeneration ◽  
Clinically Significant ◽  
Dunnett's Test

Purpose: The present study aims to assess the combined effects of mineral trioxide aggregate (MTA) and iloprost when used as a pulp capping material on pulpal inflammation and tertiary dentin formation compared with MTA and iloprost alone in rat molar teeth. Methods: Eighty maxillary first molar rat teeth were exposed and capped with iloprost solution, MTA, or MTA mixed with iloprost (MTA-iloprost). The cavities were then filled with resin-modified glass ionomer. The cavity was restored with glass ionomer without the use of pulp capping agent in the control group. The rats were sacrificed after one and four weeks. Block sections of the molar specimens were prepared and subjected to hematoxylin and eosin staining for evaluation. Statistical analysis was done using the Kruskal–Wallis test, followed by Dunnett’s test. Results: At week one, the control group showed significantly more severe pulpal inflammatory reactions than the iloprost (p = 0.00), MTA (p = 0.04), and MTA-iloprost (p = 0.00) groups. Hard tissue formation was commonly found in the iloprost, MTA, and MTA-iloprost groups. After four weeks, pulpal tissue degeneration was observed in the control group. Complete hard tissue barriers were found in 50%, 72.7%, and 77.8% of the specimens in iloprost, MTA, and MTA-iloprost groups, respectively, with no significant differences among the experimental groups. The dentinal tubule patterns were mostly regular in the MTA-iloprost group and irregular in the iloprost and MTA groups. Conclusions: The application of iloprost, MTA, and MTA-iloprost as a pulp capping material resulted in similar pulpal responses in the mechanically exposed pulp of rat molars. Therefore, mixing MTA with iloprost might not be clinically significant.

scholarly journals Apexification Using Mineral Trioxide Aggregate and Modified Internal Matrix: A Case Report

2021 ◽  
Vol 33 (2) ◽  
Keyword(s):  
Case Report ◽  
Mineral Trioxide Aggregate ◽  
Tissue Formation ◽  
Enamel Hypoplasia ◽  
Hard Tissue ◽  
Radiographic Evidence ◽  
Radiographic Findings ◽  
Immature Teeth ◽  
Patient Reported ◽  
Treatment Alternatives

When pulpal necrosis occurs in immature teeth, one of the treatment alternatives is the creation of an artificial apical barrier through the placement of an apical plug. However, controlling the mineral trioxide aggregate (MTA) during placement has proven difficult. Several studies evaluated the use of resorbable barriers to act as an internal matrix to prevent accidental extrusion of MTA. The aim of this case report was to document the effectiveness of Surgicel as a modified internal matrix for proper placement of MTA during management of immature teeth with necrotic pulp using the apical plug technique. A 12-year-old female patient reported with the chief complaint of a badly mutilated lower right second premolar. The tooth suffered enamel hypoplasia and had a defective coronal structure. It was asymptomatic except for slight tenderness to percussion. Based on the clinical and radiographic findings, a diagnosis of pulpal necrosis with symptomatic apical periodontitis was made. The 3- and 6-month followup showed radiographic evidence of continued root and hard tissue formation. Based on these findings, we infer that Surgicel can be used as a modified internal matrix to prevent extrusion of the MTA into the periapical area and allow for proper MTA placement. Keywords: Apexification; Apical plug; Mineral trioxide aggregate; Calcium hydroxide; Surgicel; Modified internal matrix

scholarly journals Temperature changes in the pulp chamber induced by polymerization of resin-based dental restoratives following simulated direct pulp capping

2019 ◽  
Vol 73 (4) ◽  
pp. 239-248
Author(s):  
Violeta Petrovic ◽  
Jovana Stasic ◽  
Vojislav Komlenic ◽  
Tatjana Savic-Stankovic ◽  
Marina Latkovic ◽  
...  
Keyword(s):  
Calcium Hydroxide ◽  
Mineral Trioxide Aggregate ◽  
Glass Ionomer ◽  
Direct Pulp Capping ◽  
Pulp Chamber ◽  
Temperature Changes ◽  
Pulp Capping ◽  
Dental Restoratives ◽  
Resin Modified Glass Ionomer ◽  
Light Curing

The objective of this study was to measure temperature changes in the pulp chamber induced by polymerization of resin-based dental restoratives following a simulated procedure of direct pulp capping. Class I cavities with a microperforation at the pulp horn were prepared in extracted human molar teeth. The complete procedure of direct pulp capping and cavity restoration was performed with the root part of extracted teeth fixed in a water bath at 37 ?C. Mineral trioxide aggregate, bioactive dentin substitute or calcium-hydroxide paste were used as pulp capping materials. Cavities were restored with a light-cured or chemically-cured resin-modified glass ionomer, universal adhesive and a bulk-fill composite, cured with a high-intensity LED unit. Pulp capping materials caused a slight temperature decrease. Lower temperature increase was recorded during light-curing of the glass ionomer liner after direct capping with mineral trioxide aggregate and calcium-hydroxide than that recorded for the bioactive dentin substitute. Adhesive light-curing increased temperature in all groups with higher mean temperatures in groups with chemically-cured as compared to those for the light-cured glass ionomer liner. Direct pulp capping with mineral trioxide aggregate or calcium-hydroxide followed by the light-cured resin-modified glass ionomer liner and a bonded bulk-fill composite restoration induced temperature changes below the potentially adverse threshold of 42.5?C.

scholarly journals Microleakage comparison of glass-ionomer and white mineral trioxide aggregate used as a coronal barrier in nonvital bleaching

2011 ◽  
pp. e1017-e1021 ◽  
Author(s):  
S. Vosoughhosseini ◽  
M. Lotfi ◽  
K. Shahmoradi ◽  
M. Saghiri ◽  
V. Zand ◽  
...  
Keyword(s):  
Mineral Trioxide Aggregate ◽  
Glass Ionomer ◽  
White Mineral

Reaction of dogs' teeth to root canal filling with mineral trioxide aggregate or a glass ionomer sealer

1999 ◽  
Vol 25 (11) ◽  
pp. 728-730 ◽  
Author(s):  
Roberto Holland ◽  
Valdir de Souza ◽  
Mauro Juvenal Nery ◽  
José Arlindo Otoboni Filho ◽  
Pedro Felício Estrada Bernabé ◽  
...  
Keyword(s):  
Root Canal ◽  
Mineral Trioxide Aggregate ◽  
Glass Ionomer ◽  
Root Canal Filling

scholarly journals Residual HEMA and TEGDMA Release and Cytotoxicity Evaluation of Resin-Modified Glass Ionomer Cement and Compomers Cured with Different Light Sources

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Murat Selim Botsali ◽  
Adem Kuşgöz ◽  
Subutay Han Altintaş ◽  
Hayriye Esra Ülker ◽  
Mehmet Tanriver ◽  
...  
Keyword(s):  
High Performance ◽  
Light Emitting Diode ◽  
Glass Ionomer Cement ◽  
Triethylene Glycol ◽  
Control Group ◽  
Light Sources ◽  
Fibroblast Cells ◽  
Glass Ionomer ◽  
Resin Modified Glass Ionomer ◽  
Ionomer Cement

The purpose of this study was first to evaluate the elution of 2-hydroxyethyl methacrylate (HEMA) and triethylene glycol dimethacrylate (TEGDMA) monomers from resin-modified glass ionomer cement (RMGIC) and compomers cured with halogen and light-emitting diode (LED) light-curing units (LCUs). The effect of cured materials on the viability of L929 fibroblast cells was also evaluated. One RMGIC (Ketac N100) and two compomers (Dyract Extra and Twinkystar) were tested. Materials were prepared in teflon disks and light-cured with LED or halogen LCUs. The residual monomers of resin materials in solution were identified using high-performance liquid chromatography. The fibroblast cells’ viability was analyzed using MTT assay. The type of LCU did not have a significant effect on the elution of HEMA and TEGDMA. A greater amount of HEMA than TEGMDA was eluted. The amount of TEGDMA eluted from Twinkystar was greater than Dyract Extra (P<0.05) when cured with a halogen LCU. All material-LCU combinations decreased the fibroblast cells’ viability more than the control group (P<0.01), except for Dyract Extra cured with a halogen LCU (P>0.05). Curing with the LED LCU decreased the cells’ viability more than curing with the halogen LCU for compomers. For Ketac N100, the halogen LCU decreased the cells’ viability more than the LED LCU.

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