scholarly journals An Attention-Based Convolutional Neural Network for Acute Lymphoblastic Leukemia Classification

2021 ◽  
Vol 11 (22) ◽  
pp. 10662
Author(s):  
Muhammad Zakir Ullah ◽  
Yuanjie Zheng ◽  
Jingqi Song ◽  
Sehrish Aslam ◽  
Chenxi Xu ◽  
...  

Leukemia is a kind of blood cancer that influences people of all ages and is one of the leading causes of death worldwide. Acute lymphoblastic leukemia (ALL) is the most widely recognized type of leukemia found in the bone marrow of the human body. Traditional disease diagnostic techniques like blood and bone marrow examinations are slow and painful, resulting in the demand for non-invasive and fast methods. This work presents a non-invasive, convolutional neural network (CNN) based approach that utilizes medical images to perform the diagnosis task. The proposed solution consisting of a CNN-based model uses an attention module called Efficient Channel Attention (ECA) with the visual geometry group from oxford (VGG16) to extract better quality deep features from the image dataset, leading to better feature representation and better classification results. The proposed method shows that the ECA module helps to overcome morphological similarities between ALL cancer and healthy cell images. Various augmentation techniques are also employed to increase the quality and quantity of training data. We used the classification of normal vs. malignant cells (C-NMC) dataset and divided it into seven folds based on subject-level variability, which is usually ignored in previous methods. Experimental results show that our proposed CNN model can successfully extract deep features and achieved an accuracy of 91.1%. The obtained findings show that the proposed method may be utilized to diagnose ALL and would help pathologists.

PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e7731 ◽  
Author(s):  
Tao Wang ◽  
Changhua Lu ◽  
Guohao Shen ◽  
Feng Hong

Sleep apnea (SA) is the most common respiratory sleep disorder, leading to some serious neurological and cardiovascular diseases if left untreated. The diagnosis of SA is traditionally made using Polysomnography (PSG). However, this method requires many electrodes and wires, as well as an expert to monitor the test. Several researchers have proposed instead using a single channel signal for SA diagnosis. Among these options, the ECG signal is one of the most physiologically relevant signals of SA occurrence, and one that can be easily recorded using a wearable device. However, existing ECG signal-based methods mainly use features (i.e. frequency domain, time domain, and other nonlinear features) acquired from ECG and its derived signals in order to construct the model. This requires researchers to have rich experience in ECG, which is not common. A convolutional neural network (CNN) is a kind of deep neural network that can automatically learn effective feature representation from training data and has been successfully applied in many fields. Meanwhile, most studies have not considered the impact of adjacent segments on SA detection. Therefore, in this study, we propose a modified LeNet-5 convolutional neural network with adjacent segments for SA detection. Our experimental results show that our proposed method is useful for SA detection, and achieves better or comparable results when compared with traditional machine learning methods.


2019 ◽  
Vol 28 (1) ◽  
pp. 3-12
Author(s):  
Jarosław Kurek ◽  
Joanna Aleksiejuk-Gawron ◽  
Izabella Antoniuk ◽  
Jarosław Górski ◽  
Albina Jegorowa ◽  
...  

This paper presents an improved method for recognizing the drill state on the basis of hole images drilled in a laminated chipboard, using convolutional neural network (CNN) and data augmentation techniques. Three classes were used to describe the drill state: red -- for drill that is worn out and should be replaced, yellow -- for state in which the system should send a warning to the operator, indicating that this element should be checked manually, and green -- denoting the drill that is still in good condition, which allows for further use in the production process. The presented method combines the advantages of transfer learning and data augmentation methods to improve the accuracy of the received evaluations. In contrast to the classical deep learning methods, transfer learning requires much smaller training data sets to achieve acceptable results. At the same time, data augmentation customized for drill wear recognition makes it possible to expand the original dataset and to improve the overall accuracy. The experiments performed have confirmed the suitability of the presented approach to accurate class recognition in the given problem, even while using a small original dataset.


2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Sorayya Rezayi ◽  
Niloofar Mohammadzadeh ◽  
Hamid Bouraghi ◽  
Soheila Saeedi ◽  
Ali Mohammadpour

Background. Leukemia is fatal cancer in both children and adults and is divided into acute and chronic. Acute lymphoblastic leukemia (ALL) is a subtype of this cancer. Early diagnosis of this disease can have a significant impact on the treatment of this disease. Computational intelligence-oriented techniques can be used to help physicians identify and classify ALL rapidly. Materials and Method. In this study, the utilized dataset was collected from a CodaLab competition to classify leukemic cells from normal cells in microscopic images. Two famous deep learning networks, including residual neural network (ResNet-50) and VGG-16 were employed. These two networks are already trained by our assigned parameters, meaning we did not use the stored weights; we adjusted the weights and learning parameters too. Also, a convolutional network with ten convolutional layers and 2 ∗ 2 max-pooling layers—with strides 2—was proposed, and six common machine learning techniques were developed to classify acute lymphoblastic leukemia into two classes. Results. The validation accuracies (the mean accuracy of training and test networks for 100 training cycles) of the ResNet-50, VGG-16, and the proposed convolutional network were found to be 81.63%, 84.62%, and 82.10%, respectively. Among applied machine learning methods, the lowest obtained accuracy was related to multilayer perceptron (27.33%) and highest for random forest (81.72%). Conclusion. This study showed that the proposed convolutional neural network has optimal accuracy in the diagnosis of ALL. By comparing various convolutional neural networks and machine learning methods in diagnosing this disease, the convolutional neural network achieved good performance and optimal execution time without latency. This proposed network is less complex than the two pretrained networks and can be employed by pathologists and physicians in clinical systems for leukemia diagnosis.


2021 ◽  
Vol 10 (2) ◽  
Author(s):  
Kiaan Upamanyu ◽  
Indukala P. Ramaswamy

The objective of this paper was to study the effectiveness of image augmentation techniques in training a Convolutional Neural Network (CNN) of a self-driving car and identify the most suitable form of image augmentation technique, using the Udacity Car Simulator. Firstly, a dataset of augmented and non-augmented images from a training track, consisting of left-, right-, and front-facing views from the car cameras was created. Various image augmentation techniques were used: zoom, brightness, pan, flip, random (augments the image by arbitrarily choosing a technique from the previous four), and no augmentation. Secondly, training datasets consisting of the aforementioned images and a log of car turning angles, throttle, and brake were built. The final training datasets were then used with NVIDIA training method to train different CNN. The different trained networks generated steering commands from the front-facing camera of the simulation and test track had no effect on the generalization of the CNN. Lastly, different trained networks were used on the test track of Udacity Car Simulator to calculate the following variables: distance travelled, and number of crashes made by the car. After these values were acquired, an efficiency analysis was performed. The results suggested augmentation of training data is a crucial factor when it comes to the process of generalizing a model to perform tasks. Random augmentations performed the best, but a combination of flip and brightness augmentations performed equally efficiently.


Author(s):  
Tang Tang ◽  
Tianhao Hu ◽  
Ming Chen ◽  
Ronglai Lin ◽  
Guorui Chen

In recent years, deep learning-based fault diagnosis methods have drawn lots of attention. However, for most cases, the success of machine learning-based models relies on the circumstance that training data and testing data are under the same working condition, which is too strict for real implementation cases. Combined with the features of robustness of deep convolutional neural network and vibration signal characteristics, information fusion technology is introduced in this study to enhance the feature representation capability as well as the transferability of diagnosis models. With the basis of multi-sensors and narrow-band decomposition techniques, a convolutional architecture named fusion unit is proposed to extract multi-scale features from different sensors. The proposed method is tested on two data sets and has achieved relatively higher generalization ability when compared with several existing works, which demonstrates the effectiveness of our proposed fusion unit for feature extraction on both source task and target task.


Author(s):  
Syadia Nabilah Mohd Safuan ◽  
Mohd Razali Md Tomari ◽  
Wan Nurshazwani Wan Zakaria ◽  
Mohd Norzali Hj Mohd ◽  
Nor Surayahani Suriani

Acute Lymphoblastic Leukemia (ALL) is a disease that is defined by uncontrollable growth of malignant and immature White Blood Cells (WBCs) which is called lymphoblast. Traditionally, lymphoblast analysis is done manually and highly dependent on the pathologist’s skill and  experience which sometimes yields inaccurate result. For that reason, in this project an algorithm to automatically detect WBC and subsequently examine ALL disease using Convolutional Neural Network (CNN) is proposed. Several pretrained CNN models which are VGG, GoogleNet and Alexnet were analaysed to compare its performance for differentiating lymphoblast and non-lymphoblast cells from IDB database. The tuning is done by experimenting the convolution layer, pooling layer and fully connected layer. Technically, 70% of the images are used for training and another 30% for testing. From the experiments, it is found that the best pretrained models are VGG and GoogleNet compared to AlexNet by achieving 100% accuracy for training. As for testing, VGG obtained the highest performance which is 99.13% accuracy. Apart from that, VGG also proven to have better result based on the training graph which is more stable and contains less error compared to the other two models.


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