scholarly journals Orbicularis Oculi Muscle Size and Function: Exploring the Influence of Aging and Exercise Training

Cosmetics ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. 29
Author(s):  
Takashi Abe ◽  
Jeremy P. Loenneke
Keyword(s):  
Older Adults ◽  
Exercise Training ◽  
Muscle Hypertrophy ◽  
Peak Velocity ◽  
Muscle Thickness ◽  
Muscle Size ◽  
Sphincter Muscle ◽  
Orbicularis Oculi Muscle ◽  
Orbicularis Oculi ◽  
And Function

The orbicularis oculi muscle is the sphincter muscle of the eyelids that blinks and closes the eyes. In this review, our aim was threefold: (1) to introduce the performance characteristics of blinking activity in young and older adults, (2) to discuss the influence of aging on the orbicularis oculi muscle in healthy adults, and (3) to provide information about the effect of facial exercise training on the orbicularis oculi muscle. To achieve the purpose of this review, a search using two electronic databases (PubMed and Scopus) and a search engine (Google Scholar) was conducted. The amplitude and peak velocity of spontaneously blinking behavior, which is an index of muscle function of the orbicularis oculi, appear to be affected by aging. The muscle thickness of the orbicularis oculi tends to be low in older adults, but there are issues that need to be examined further, such as differences in sex and measurement positions. There was no study on the effect of exercise training; however, the results of a highly trained man indicate that the orbicularis oculi muscles might elicit muscle hypertrophy through non-traditional resistance exercise.

scholarly journals Muscular Atrophy and Sarcopenia in the Elderly: Is There a Role for Creatine Supplementation?

Biomolecules ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. 642 ◽  
Author(s):  
Dolan ◽  
Artioli ◽  
Pereira ◽  
Gualano
Keyword(s):  
Older Adults ◽  
Exercise Training ◽  
Energy Demand ◽  
Muscular Atrophy ◽  
Training Stimulus ◽  
Creatine Supplementation ◽  
The Elderly ◽  
High Energy ◽  
Age Related ◽  
And Function

Sarcopenia is characterized by a loss of muscle mass, quality, and function, and negatively impacts health, functionality, and quality of life for numerous populations, particularly older adults. Creatine is an endogenously produced metabolite, which has the theoretical potential to counteract many of the morphological and metabolic parameters underpinning sarcopenia. This can occur through a range of direct and indirect mechanisms, including temporal and spatial functions that accelerate ATP regeneration during times of high energy demand, direct anabolic and anti-catabolic functions, and enhanced muscle regenerating capacity through positively impacting muscle stem cell availability. Studies conducted in older adults show little benefit of creatine supplementation alone on muscle function or mass. In contrast, creatine supplementation as an adjunct to exercise training seems to augment the muscle adaptive response to the training stimulus, potentially through increasing capacity for higher intensity exercise, and/or by enhancing post-exercise recovery and adaptation. As such, creatine may be an effective dietary strategy to combat age-related muscle atrophy and sarcopenia when used to complement the benefits of exercise training.

Treatment of Orbicularis Oculi Muscle Hypertrophy in Lower Lid Blepharoplasty

1998 ◽  
Vol 22 (5) ◽  
pp. 349-351 ◽  
Author(s):  
Claudio Bernardi ◽  
Stefano Dura ◽  
Pier Luigi Amata
Keyword(s):  
Muscle Hypertrophy ◽  
Orbicularis Oculi Muscle ◽  
Orbicularis Oculi ◽  
Lower Lid Blepharoplasty

Evidence of a Ceiling Effect for Training Volume in Muscle Hypertrophy and Strength in Trained Men—Less is More?

2020 ◽  
Vol 15 (2) ◽  
pp. 268-277 ◽  
Author(s):  
Matheus Barbalho ◽  
Victor S. Coswig ◽  
James Steele ◽  
James P. Fisher ◽  
Jurgen Giessing ◽  
...  
Keyword(s):  
Resistance Training ◽  
Muscle Hypertrophy ◽  
Biceps Brachii ◽  
Gluteus Maximus ◽  
Muscle Thickness ◽  
Muscle Performance ◽  
Muscle Size ◽  
Triceps Brachii ◽  
Less Is More ◽  
Time Interaction

Purpose: To compare the effects of different resistance training volumes on muscle performance and hypertrophy in trained men. Methods: Thirty-seven volunteers performed resistance training for 24 weeks, divided into groups that performed 5 (G5), 10 (G10), 15 (G15), and 20 (G20) sets per muscle group per week. Ten-repetition maximum (10RM) tests were performed for the bench press, lat pulldown, 45° leg press, and stiff-legged deadlift. Muscle thickness was measured using ultrasound at biceps brachii, triceps brachii, pectoralis major, quadriceps femoris, and gluteus maximus. All measurements were performed at the beginning (pre), 12 (mid), and 24 weeks (post) of training. Results: All groups showed significant increases in all 10RM tests and muscle thickness measures after 12 and 24 weeks when compared with pre (P < .05). There were no significant differences in any 10RM test or changes between G5 and G10 after 12 and 24 weeks. G5 and G10 showed significantly greater increases for 10RM than G15 and G20 for most exercises at 12 and 24 weeks. There was no group by time interaction for any muscle thickness measure. Conclusions: The results bring evidence of an inverted “U-shaped” curve for the dose–response curve for muscle strength. Although the same trend was noted for muscle hypertrophy, the results did not reach significance. Five to 10 sets per week might be sufficient for bringing about optimal gains in muscle size and strength in trained men over a 24-week period.

No histological evidence of orbicularis oculi muscle hypertrophy in congenital epiblepharon

2012 ◽  
Vol 41 (2) ◽  
pp. 167-171 ◽  
Author(s):  
Hirohiko Kakizaki ◽  
Yasuhiro Takahashi ◽  
Hyera Kang ◽  
Hiroshi Ikeda ◽  
Masayoshi Iwaki ◽  
...  
Keyword(s):  
Muscle Hypertrophy ◽  
Orbicularis Oculi Muscle ◽  
Orbicularis Oculi ◽  
Histological Evidence

Assessing differential responders and mean changes in muscle size, strength, and the crossover effect to 2 distinct resistance training protocols

2020 ◽  
Vol 45 (5) ◽  
pp. 463-470 ◽  
Author(s):  
Scott J. Dankel ◽  
Zachary W. Bell ◽  
Robert W. Spitz ◽  
Vickie Wong ◽  
Ricardo B. Viana ◽  
...  
Keyword(s):  
Resistance Training ◽  
Random Error ◽  
Muscle Hypertrophy ◽  
Muscle Thickness ◽  
Exercise Group ◽  
Muscle Size ◽  
Control Group ◽  
Crossover Effect ◽  
Traditional Group ◽  
Training Protocols

The objective of this study was to determine differences in 2 distinct resistance training protocols and if true variability can be detected after accounting for random error. Individuals (n = 151) were randomly assigned to 1 of 3 groups: (i) a traditional exercise group performing 4 sets to failure; (ii) a group performing a 1-repetition maximum (1RM) test; and (iii) a time-matched nonexercise control group. Both exercise groups performed 18 sessions of elbow flexion exercise over 6 weeks. While both training groups increased 1RM strength similarly (∼2.4 kg), true variability was only present in the traditional exercise group (true variability = 1.80 kg). Only the 1RM group increased untrained arm 1RM strength (1.5 kg), while only the traditional group increased ultrasound measured muscle thickness (∼0.23 cm). Despite these mean increases, no true variability was present for untrained arm strength or muscle hypertrophy in either training group. In conclusion, these findings demonstrate the importance of taking into consideration the magnitude of random error when classifying differential responders, as many studies may be classifying high and low responders as those who have the greatest amount of random error present. Additionally, our mean results demonstrate that strength is largely driven by task specificity, and the crossover effect of strength may be load dependent. Novelty Many studies examining differential responders to exercise do not account for random error. True variability was present in 1RM strength gains, but the variability in muscle hypertrophy and isokinetic strength changes could not be distinguished from random error. The crossover effect of strength may differ based on the protocol employed.

Kinematics of spontaneous, reflex, and conditioned eyelid movements in the alert cat

1995 ◽  
Vol 74 (1) ◽  
pp. 226-248 ◽  
Author(s):  
A. Gruart ◽  
P. Blazquez ◽  
J. M. Delgado-Garcia
Keyword(s):  
Rise Time ◽  
Peak Velocity ◽  
Emg Activity ◽  
Orbicularis Oculi Muscle ◽  
Upper Eyelid ◽  
Orbicularis Oculi ◽  
Conditioned Eyelid ◽  
Integrated Emg ◽  
Alert Cats ◽  
Stimulus Offset

1. Upper eyelid position and velocity, and the electromyographic (EMG) activity of the orbicularis oculi muscle, were recorded bilaterally in alert cats during spontaneous, reflexively evoked, and conditioned eyelid movements. 2. Spontaneous blinks appeared randomly (0.2-0.5 per min) and consisted of a fast, large downward lid movement followed by a slower up phase. Blinks of smaller amplitude and slower velocity were also observed mainly accompanying behavioral movements, such as during peering and grimacing. 3. Eyelid response to air puffs applied to the cornea and tarsal lid skin consisted of a short-latency (9-16 ms), fast (up to 2,000 degrees/s) downward movement that lasted for 25-30 ms, followed by late, small downward sags that were sometimes still evident after stimulus offset. Blinks outlasted the duration of the stimulus by approximately 150 ms. Blinks elicited by flashes of light or tones showed longer latency (47.3 +/- 6.3 and 53.7 +/- 8.0 ms, mean +/- SD; respectively), smaller amplitude, and a quicker habituation than air-puff-evoked lid responses. 4. For the down phase of the blink, the peak velocity, but not its duration, increased linearly with blink amplitude. Because the rise time of the down phase remained constant, changes in blink amplitude seemed to be the result of increased blink velocity. The down phase of a typical 10 degrees blink was 10 times faster than the up phase of the same blink or than upward and downward lid saccades of the same amplitude. The peak velocity and duration of the up phases of reflex blinks and upward and downward lid saccades increased linearly with lid movement amplitude. 5. The initial down phase of air-puff-evoked blinks decreased in latency, increased in amplitude and peak velocity, and maintained the same rise time for increasing puff pressure. None of these parameters was dependent on puff duration. The duration of the blink also increased linearly with air puff duration. 6. The amplitude of air-puff-evoked blinks was inversely related to lid position, decreasing with further lid positions in the closing direction. In contrast, neither peak nor integrated EMG activity of the orbicularis oculi muscle was affected by lid position, being only a function of stimulus parameters and of the animal's level of alertness. 7. Air puffs > 20 ms and > 1 kg/cm2 evoked two successive bursts (R(ap) 1 and R(ap) 2) in the EMG activity of the orbicularis oculi muscle. Shorter and/or weaker stimuli evoked only the R(ap) 1 response.(ABSTRACT TRUNCATED AT 400 WORDS)

scholarly journals Age-related external anal sphincter muscle dysfunction and fibrosis: possible role of Wnt/β-catenin signaling pathways

2017 ◽  
Vol 313 (6) ◽  
pp. G581-G588 ◽  
Author(s):  
M. Raj Rajasekaran ◽  
Sadhana Kanoo ◽  
Johnny Fu ◽  
My-Uyen (Lilly) Nguyen ◽  
Valmik Bhargava ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Anal Canal ◽  
Anal Sphincter ◽  
External Anal Sphincter ◽  
Muscle Thickness ◽  
Sphincter Muscle ◽  
Anal Sphincter Muscle ◽  
Age Related ◽  
And Function

Studies show an age-related increase in the prevalence of anal incontinence and sphincter muscle atrophy. The Wnt/β-catenin signaling pathway has been recently recognized as the major molecular pathway involved in age-related skeletal muscle atrophy and fibrosis. The goals of our study were to 1) evaluate the impact of normal aging on external anal sphincter (EAS) muscle length-tension (L-T) function and morphology and 2) specifically examine the role of Wnt signaling pathways in anal sphincter muscle fibrosis. New Zealand White female rabbits [6 young (6 mo of age) and 6 old (36 mo of age)] were anesthetized, and anal canal pressure was measured to determine the L-T function of EAS. Animals were killed at the end of the study, and the anal canal was harvested and processed for histochemical studies (Masson trichrome stain for muscle/connective tissue) as well as for molecular markers for fibrosis and atrophy [collagen I, β-catenin, transforming growth factor-β (TGF-β), atrogin-1, and muscle-specific RING finger protein-1 (MuRF-1)]. The L-T was significantly impaired in older animals compared with young animals. Anal canal sections stained with trichrome showed a significant decrease in the muscle content (52% in old compared with 70% in young) and an increase in the connective tissue/collagen content in the old animals. An increased protein and mRNA expression of all the fibrosis markers was seen in the older animals. Aging EAS muscle exhibits impairment of function and increase in connective tissue. Upregulation of atrophy and profibrogenic proteins with aging may be the reason for the age-related decrease in anal sphincter muscle thickness and function. NEW & NOTEWORTHY Our studies using a female rabbit model show age-related alterations in the structure and function of the external anal sphincter (EAS) muscle. We used endoluminal ultrasound to measure age-related changes in EAS muscle thickness. We employed Western blot and quantitative PCR to demonstrate age-related changes in the levels of important fibrogenic as well as atrophy markers. Our findings may have significant clinical implications, i.e., use of specific antagonists to prevent age-related EAS muscle dysfunction.

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