scholarly journals Screening for Melanoma and Other Skin Cancer Shows a Higher Early Melanoma Incidence: Social Educational Program “Life Fear-Free”

2021 ◽  
Vol 8 (1) ◽  
pp. 54-68
Author(s):  
Lev Demidov ◽  
Igor Samoylenko ◽  
Nina Vand ◽  
Igor Utyashev ◽  
Irina Shubina ◽  
...  

Background: The screening program Life Fear-Free (LFF) aimed at early diagnosis of cutaneous melanoma (CM) was introduced in Samara, Chelyabinsk, Yekaterinburg, and Krasnodar (Russia) in 2019. Objectives: To analyze the impact of the program on early CM and non-melanoma skin cancer (NMSC) detection. Methods: According to the social educational campaign, people were informed about CM risk factors and symptoms and were invited for skin examination. The program planned to involve 3200 participants in total. Participants with suspicious lesions were invited for excisional biopsy. Results: 3143 participants, including 75.4% women, were examined for skin lesions. The average age of the participants was 43.7 years. Mostly skin phototypes II and III were registered (48.2% and 41.0%, respectively); 3 patients had CM, 15 had basal cell carcinoma, and 1 had Bowen’s disease, which were confirmed histologically. All detected melanomas had Breslow’s thickness of 1 mm. Conclusion: The participants showed high interest in early skin cancer detection programs. The incidence rate of CM and NMSCs among the program participants was higher than in general public. The early disease grade was proven for the detected CMs and NMSCs. The study has shown that it is important to continue such programs.

Cosmetics ◽  
2019 ◽  
Vol 6 (3) ◽  
pp. 42 ◽  
Author(s):  
Paola Perugini ◽  
Margherita Bonetti ◽  
Arianna Cecilia Cozzi ◽  
Giorgio Lorenzo Colombo

Background: Avoiding extended exposure to direct sunlight and the topical application of sunscreen when exposed are the main techniques used to protect the skin form sunburn, photoaging, and skin cancer risk (melanoma and non-melanoma skin cancer). Preventive strategies could lead to a significant reduction of the excessive health system cost for the treatment of these conditions. Sunscreen employment and efficacy stay controversial despite decades of humane use with health benefits closely related. At the present, few studies still found a connection between the use of sunscreen and not significant long-term benefits from UV induced damages. Objectives: To assess the effects of sunscreens for preventing melanoma, non-melanoma skin cancer (basal or squamous carcinoma and melanoma) and precancerous skin lesions. Method: Published literature (1993–2017) was reviewed and eligible studies that reported the impact of sunscreen use in the prevention of melanoma, non-melanoma skin cancer, or precancerous skin lesion were selected. Result: Starting from 532 sources, a total of seven articles met the inclusion criteria and they have been subjected to a systematic review. All of the included studies suggest that sunscreen use is associated with a reduction in melanoma, squamous cell carcinoma, and precancerous skin lesions; however, the difficulties in evaluating the efficiency of sunscreen were pointed out. Conclusion: The review of the experimental evidence supports the topical application of sunscreen as an effective effort in preventing skin cancer and precancerous skin lesions.


Author(s):  
Indula Subash ◽  
L. C. Manikandan

Skin cancers are generally grouped into either melanoma or non-melanoma skin cancers. Melanoma skin cancers comprise a higher rate of mortality, while non-melanoma skin cancers have a higher frequency rate. This paper describes different methods for the detection and classification of melanoma and non-melanoma skin cancer.


2021 ◽  
Author(s):  
Vanessa Gorasso ◽  
Geert Silversmit ◽  
Marc Arbyn ◽  
Astrid Cornez ◽  
Robby De Pauw ◽  
...  

Abstract Background The importance of assessing and monitoring the health status of a population has grown in the last decades. Consistent and high quality data on the morbidity and mortality impact of a disease represent the key element for this assessment. Being increasingly used in global and national burden of diseases (BoD) studies, the Disability-Adjusted Life Year (DALY) is an indicator that combines healthy life years lost due to living with disease (Years Lived with Disability; YLD) and due to dying prematurely (Years of Life Lost; YLL). As a step towards a comprehensive national burden of disease study, this study aims to estimate the non-fatal burden of cancer in Belgium using national data. Methods We estimated the Belgian cancer burden from 2004 to 2018 in terms of YLD, using national population-based cancer registry data and international disease models. We developed a microsimulation model to translate incidence- into prevalence-based estimates, and used expert elicitation to integrate the long-term impact of increased disability due to surgical treatment. Results The age-standardized non-fatal burden of cancer increased from 2004 to 2018 by 6% and 2% respectively for incidence- and prevalence-based YLDs. In 2018, in Belgium, breast cancer had the highest morbidity impact among women, followed by colorectal and non-melanoma skin cancer. Among men, prostate cancer had the highest morbidity impact, followed by colorectal and non-melanoma skin cancer. Between 2004 and 2018, non-melanoma skin cancer significantly increased for both sexes in terms of age-standardized incidence-based YLD per 100,000, from 48 to 107 for men and from 15 to 37 for women. Important decreases were seen for colorectal cancer for both sexes in terms of age-standardized incidence-based YLD per 100,000, from 104 to 85 for men and from 52 to 46 for women. Conclusions Breast and prostate cancers represent the greatest proportion of cancer morbidity, while for both sexes the morbidity burden of skin cancer has shown an important increase from 2004 onwards. Integrating the current study in the Belgian national burden of disease study will allow monitoring of the burden of cancer over time, highlighting new trends and assessing the impact of public health policies.


The email service is a core platform for Mass communication as a consequence of which, it becomes central Target of all the social engineering and phishing attacks. As a consequence, attackers can try to impersonate or fake a trusted identity to carry out highly sophisticated and deceptive phishing attacks via Email Spoofing. In this work, we analyze: (1) how different Email providers detect and deal with such attacks? (2) Existing protection techniques and what is its scope of effectiveness? (3) Under Which conditions do spoofed emails reach inbox and its potential consequences? (4) Best practices and Adaptability apart from existing methods to remain secure. We address this concern by considering the parameters of top 25 email services (Used by more than billions of users) and also real world experiments. The existing protocols, security layers and the restrictions based on detection methods. The scale of implications by allowing the forged emails to enter the inbox despite getting detected by layers of SPF, DKIM, DMARC and ARC. The extent of problems caused in different paradigms, and the potential of having just SMTP implemented without any additional security layers within the domains. The impact of Misleading UI for allowed spoofed emails by providers is also discussed briefly. We observe the impression of security when users are caught off guard in real world testing on domains (eg. Gmail, Hotmail, Yahoo mail, etc ) by simple platforms to spoof (eg. emkei.cz) apart from discussing the anomalous behavior of gmail as a response. We have conducted experiment to analyze behavior of top email domains against spoofed emails of various types


2020 ◽  
Author(s):  
Tiberiu Tamas ◽  
Cristian Dinu ◽  
Manuela Lenghel ◽  
Grigore Băciuț ◽  
Simion Bran ◽  
...  

Non-Melanoma Skin Cancer is one of the most common cancer types and the face is the most affected region. The diagnosis of the skin cancer relies on clinical inspection, palpation, dermoscopy followed by incisional or excisional biopsy. When skin cancers are removed from the face, many factors are involved, including aesthetics. In addition, surgical planning with preoperative acknowledgement of the tumour margins is often the key to avoid incomplete excision, the need for reintervention, or in the prevention of functional and aesthetical defects in the treatment of skin tumours. In recent years, the development of new technologies in sonography, including high frequencies transducers can provide a full range of data. It can offer valuable information regarding the size of the tumour including the depth of invasion, the extent of the tumour, histology and subtypes of the lesions which are helpful for the treatment plan. It also may be efficient in detection of positive margins after surgery and it could play a role in the treatment of skin cancer, prevention of local recurrences and overall control of the disease. K


2018 ◽  
Vol 7 (4) ◽  
pp. 41-50
Author(s):  
E. A. Gromova ◽  
I. V. Gagulin ◽  
A. V. Gafarova ◽  
D. O. Panov ◽  
V. V. Gafarov

Aim. To identify the impact of gender differences in family stress on the risk profle of arterial hypertension (AH) in the general population aged 25–64 years in Russia / Siberia.Methods. A random representative sample of the Novosibirsk population of both sexes aged 25–64 (men: n = 657, 44.3±0.4 years, response rate – 82.1%; women: n = 689, 45.4±0.4 years, response rate ‒ 72.5%) was screened in the WHO “MONICApsychosocial program” in 1994. The screening program included the collection of social and demographic data and assessment of family stress. 229 new cases of arterial hypertension in women and 46 cases in men have been determined within the 16-year follow-up.Results. Men (31.5%) had higher level of family stress in the general population aged 25–64, than women (20.9%). In the 16-year period, the risk of hypertension was higher in men (HR = 2.24) than women (HR = 1.39) exposed to family stress. After the adjustment to the social status and age, the risk of developing hypertension remained higher in men than in women (RR = 1.9 vs. HR = 1.37, respectively). Divorced and widowed men had the highest risk of arterial hypertension compared to women aged 45–54 years (HR = 12.7 vs. HR = 10.6 vs. HR = 2.86, respectively).Conclusion. Family stress is more common in men than in women. Risk of arterial hypertension is higher in men than in women who experienced family stress.


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