scholarly journals Comparison of Two Different Semiquantitative Urinary Dipstick Tests with Albumin-to-Creatinine Ratio for Screening and Classification of Albuminuria According to KDIGO. A Diagnostic Test Study

Diagnostics ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 81
Author(s):  
Nikolai C. Hodel ◽  
Ali Hamad ◽  
Klaus Reither ◽  
Irene Mndala Kasella ◽  
Salim Abdulla ◽  
...  

Background: Semiquantitative dipstick tests are utilized for albuminuria screening. Methods: In a prospective cross-sectional survey, we analyzed the diagnostic test validity of the semiquantitative colorimetric indicator-dye-based Combur9-Test® and the albumin-specific immunochromatographic assay Micral-Test® for the detection of albuminuria, the distribution of the semiquantitative measurements within the albuminuria stages according to KDIGO, and the utility for albuminuria screening compared with an albumin-to-creatinine ratio (ACR) in a walk-in population. Results: In 970 subjects, albuminuria (≥30 mg/g) was detected in 12.7% (95% CI 85.6–96.3%) with the ACR. Sensitivity was 82.9% (95% CI 75.1–89.1%) and 91.9% (95% CI 88.7–96.9%) and specificity 71.5% (95% CI 68.4–74.6%) and 17.5% (95% CI 15.0–20.2%) for the Combur9-Test® and Micral-Test®, respectively. Correct classification to KDIGO albuminuria stages A2/A3 with the Combur9-Test® was 15.4%, 51.4%, and 87.9% at cut-offs of 30, 100, and ≥300 mg/dL, and with the Micral-Test® it was 1.8%, 10.5%, and 53.6% at cut-offs of 2, 5, and 10 mg/dL, respectively. Overall, disagreement to KDIGO albuminuria was seen in 27% and 73% with the Combur9-Test® and Micral-Test®, respectively. From the total population, 62.5% and 15.3% were correctly ruled out and 2.2% and 1% were missed as false-negatives by the Combur9-Test® and Micral-Test®, respectively. Conclusion: Compared to the Combur9-Test®, the utility of the Micral-Test® is limited, because the fraction of correctly ruled out patients is small and a large proportion with a positive Micral-Test® require a subsequent ACR conformation test.

2011 ◽  
Vol 14 (12) ◽  
pp. 2254-2259 ◽  
Author(s):  
Anna C Holland ◽  
Matthew C Kennedy ◽  
Stephen W Hwang

AbstractObjectiveTo compare the Household Food Insecurity Access Scale (HFIAS), the US Food Security Survey Module (US FSSM) and a modified version of the US FSSM in which references to buying food were changed to references to getting food, in terms of their classification of food security levels among homeless individuals, and to determine which of these instruments was most preferred by homeless individuals.DesignA cross-sectional survey.SettingRecruitment of participants took place at seven shelters and from three drop-in programmes that serve homeless individuals in Toronto, Canada.SubjectsFifty individuals who were ≥18 years of age, able to communicate in English and currently homeless.ResultsThe modified US FSSM assigned 20 % of participants to a lower ordinal food security category compared with the US FSSM, and only 8 % to a higher food security category. The HFIAS assigned 30 % of participants to a lower food security category compared with either the US FSSM or the modified US FSSM, and only 10–16 % of participants to a higher food security category. When asked to compare all three instruments, the majority of respondents (62 %) selected the HFIAS as the best instrument for people who are homeless.ConclusionsA majority of homeless individuals selected the HFIAS as the best food security instrument for people who are homeless. Our findings suggest that the HFIAS is a more appropriate instrument than the US FSSM for measuring food security in the homeless population.


2021 ◽  
Vol 9 ◽  
Author(s):  
Markus Wübbeler ◽  
Sebastian Geis ◽  
Jovana Stojanovic ◽  
Lise Elliott ◽  
Iñaki Gutierrez-Ibarluzea ◽  
...  

Introduction: An important requirement for successful public health interventions is a standardized classification in order to make these health technologies comparable in all contexts and recognized by all parties. The WHO International Classification of Health Interventions (ICHI), including an integrated public health component, has been developed to propose such an international standard.Methods: To test (a) the translation of public health interventions to ICHI codes and (b) the technical handling and general coding in public health, we used a set of public health interventions from a recent cross-sectional survey among Health Technology Assessment professionals.Results: Our study showed that handling of the ICHI interface is stable, that there is a need for specificity and adequate detail of intervention descriptions and desired outcomes to code adequately with ICHI and that the professional background of the coder, as well as his/her sex might influence the selection of codes.Conclusion: International Classification of Health Interventions provides a good coverage of public health interventions. However, the broader character of system wide interventions, often involving a variety of institutions and stakeholders, may present a challenge to the application of ICHI coding. Based on this experience, we would tailor future surveys more specifically to the needs of the classification and we advise training for health professionals before coding with ICHI. Standards of reporting will likely strengthen insights about the efficiency of primary prevention interventions and thus benefit long-term health of populations and structured HTA reporting process.


2017 ◽  
Vol 2 (2) ◽  
pp. 94-97
Author(s):  
Nazmul Haque ◽  
Narayan Chandra Saha ◽  
Mohammad Ekhlasur Rahman ◽  
Tahmina Ahmed

Background: Mean corpuscular volume (MCV) and mean corpuscular haemoglobin (MCH) of red blood cell is the useful diagnostic test which is performed during routine blood examination.Objective: The purpose of the present study was to measure the diagnostic test validity of MCV for the determination of thalassaemia carrier. Methodology: This analytic cross-sectional study was carried out in the Department of Pediatrics and Department of Medicine at MAG Osmani Medical College Hospital, Sylhet, Bangladesh from September 2007 to January 2009 for a period of one year and five months. Siblings and cousins of beta Thalassemia major and Hb- E -beta Thalassemia satisfying the selection criteria were enrolled. The detailed history and thorough physical examination were done meticulously. Five (5) mL blood was drawn from each case and control for determination of MCV and Hb-Electrophoresis. Result: Total 63 were enrolled as cases and total 65 were enrolled as controls. Sensitivity, specificity, positive and negative predictive value of MCV in determination of thalassemic carriers were 92%, 89.2%, 89.2% and 92% respectively. The area under the curve value was 0.094 (0.035 to 0.152). Conclusion: In conclusion the diagnostic test validity of MCH and MCH is high in determination of Thalassemic carrier. Journal of National Institute of Neurosciences Bangladesh, 2016;2(2): 94-97]


2020 ◽  
Vol 9 (6) ◽  
pp. 7-7
Author(s):  
Anouk Overbeek ◽  
Veerle E. van de Wetering ◽  
Johannes J. M. van Delden ◽  
Paul A. M. Mevis ◽  
Bregje D. Onwuteaka-Philipsen ◽  
...  

Author(s):  
Fábio J. AMORIM ◽  
Lincoln C. SANTOS ◽  
Fernando ARAÚJO-NETO ◽  
Lucimara M. ANDRADE ◽  
Dyego C. ARAÚJO ◽  
...  

Objective: To characterize compliance with good practices in medical gas management in federal teaching hospitals in Brazil. Methods: A cross-sectional survey-type study, designed to perform a situational diagnosis of the pharmacy services in 40 federal teaching hospitals in Brazil linked to the Brazilian Hospital Services Company, with respect to compliance with good practices in gas management, through the application of the ABPGasMed 1.0 instrument. This instrument consists of 54 compliance standards divided into two sections (structure and process). The characterization of research participants and hospitals, and the classification of hospitals in terms of performance categories were expressed as absolute and relative values. Chi-square tests of independence were performed to investigate the association between the hospital’s performance category and the hospital’s geographic region and size. Results: In total, 87.5% of the invited hospitals participated in the study, and only 27.59% of the hospitals had a pharmacist responsible for medicinal gases. Pharmacovigilance was performed by pharmacists in 20.59% of the hospitals. Analyzing the hospitals by region of the country and size, statistically significant associations were found between the general classification of hospitals and the geographic region (x2(8)=18.936, p= 0.015), as well as the classification of the hospital and structure and size (x2(9)= 20.373, p= 0.016). Analyses of the adjusted standardized residues returned an association between the southeastern region and the satisfactory performance category when analyzing the entire instrument, and between the excellent performance category in the structure section and size of a small hospital. Conclusion: In most of the hospitals studied, management of medicinal gases did not show the desired performance, which indicates the need to comply with current healthcare legislations and improve the provided services. It is believed that compliance rates may evolve training of healthcare team members, with an emphasis on the pharmacist.


2021 ◽  
Vol 13 (23) ◽  
pp. 13422
Author(s):  
Lan Nguyen ◽  
Hans De Steur

This study aims to assess the public acceptability of interventions to reduce sugary drinks in Vietnam, identify the key determinants, and develop a classification of consumers. A cross-sectional survey with 263 urban consumers evaluated perceptions of four potential interventions: restricting choice, taxation, nudging, and labeling. Thereby, specific attention was devoted to perceived intrusiveness and (personal and societal) effectiveness, as well personal characteristics, including Confucius values. Results showed that “hard” interventions like taxation are less acceptable to consumers than “soft” measures such as labeling. Acceptability is generally affected by perceived intrusiveness and effectiveness (especially on other people in the society), while other factors (sugary drink behavior, trust in government’s competence, personal values, age, education) only matter for some of the interventions. Cluster analysis revealed three consumer segments, depicted as anti-taxation (28%), pro-intervention (20%) and pro-labeling (52%), which further underpins the heterogeneity of intervention acceptability.


Geriatrics ◽  
2019 ◽  
Vol 4 (1) ◽  
pp. 23 ◽  
Author(s):  
Junko Ueshima ◽  
Keisuke Maeda ◽  
Hidetaka Wakabayashi ◽  
Shinta Nishioka ◽  
Saori Nakahara ◽  
...  

(1) Background: It is important to assess physical and nutritional status using the Comprehensive Geriatric Assessment (CGA). However, the correlation between the CGA usage and nutritional-related assessments remain unclear. This study aims to clarify the correlation between the CGA usage and other nutritional-related assessments. (2) Methods: We conducted a questionnaire survey on clinical use of CGA, assessment of sarcopenia/sarcopenic dysphagia/cachexia, and defining nutritional goals/the Nutrition Care Process/the International Classification of Functioning, Disability, and Health (ICF)/the Kuchi–Kara Taberu Index. (3) Results: The number of respondents was 652 (response rate, 12.0%), including 77 who used the CGA in the general practice. The univariate analyses revealed that participants using the CGA tended to assess sarcopenia (P = 0.029), sarcopenic dysphagia (P = 0.001), and define nutritional goals (P < 0.001). Multivariate logistic regression analyses for the CGA usage revealed that using ICF (P < 0.001), assessing sarcopenia (P = 0.001), sarcopenic dysphagia (P = 0.022), and cachexia (P = 0.039), and defining nutritional goals (P = 0.001) were statistically significant after adjusting for confounders. (4) Conclusions: There are correlations between the use of CGA and evaluation of sarcopenia, sarcopenic dysphagia, and cachexia and nutritional goals.


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