scholarly journals Percutaneous CT Fluoroscopy-Guided Core Needle Biopsy of Mediastinal Masses: Technical Outcome and Complications of 155 Procedures during a 10-Year Period

Diagnostics ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 781
Author(s):  
Caroline Burgard ◽  
Robert Stahl ◽  
Giovanna Negrao de Figueiredo ◽  
Julien Dinkel ◽  
Thomas Liebig ◽  
...  
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Diagnostic Yield ◽  
Lesion Size ◽  
Histopathological Diagnosis ◽  
Safe Procedure ◽  
Ct Fluoroscopy ◽  
Mediastinal Tumors ◽  
Core Needle ◽  
Mediastinal Masses

Purpose: To evaluate technical outcome, diagnostic yield and safety of computed tomographic fluoroscopy-guided percutaneous core needle biopsies in patients with mediastinal masses. Methods: Overall, 155 CT fluoroscopy-guided mediastinal core needle biopsies, performed from March 2010 to June 2020 were included. Size of lesion, size of needle, access path, number of success, number of biopsies per session, diagnostic yield, patient’s position, effective dose, rate of complications, tumor localization, size of tumor and histopathological diagnosis were considered. Post-interventional CT was performed, and patients observed for any complications. Complications were classified per the Society of Interventional Radiology (SIR). Results: 148 patients (age, 54.7 ± 18.2) underwent 155 CT-fluoroscopy-guided percutaneous biopsies with tumors in the anterior (114; 73.5%), middle (17; 11%) and posterior (24; 15.5%) mediastinum, of which 152 (98%) were technically successful. For placement of the biopsy needle, in 82 (52.9%) procedures a parasternal trajectory was chosen, in 36 (23.3%) a paravertebral access, in 20 (12.9%) through the lateral intercostal space and in 17 (11%) the thoracic anterior midline, respectively. A total of 136 (89.5%) of the biopsies were considered adequate for a specific histopathologic analysis. Total DLP (dose-length product) was 575.7 ± 488.8 mGy*cm. Mean lesion size was 6.0 ± 3.3 cm. Neoplastic pathology was diagnosed in 115 (75.7%) biopsies and 35 (23%) biopsy samples showed no evidence of malignancy. Minor complications were observed in 18 (11.6%) procedures and major pneumothorax requiring drainage insertion in 3 interventions (1.9%). Conclusion: CT fluoroscopy-guided percutaneous core needle biopsy of mediastinal masses is an effective and safe procedure for the initial assessment of patients with mediastinal tumors.

scholarly journals Contrast-Enhanced Ultrasound Improves the Pathological Outcomes of US-Guided Core Needle Biopsy That Targets the Viable Area of Anterior Mediastinal Masses

2018 ◽  
Vol 2018 ◽  
pp. 1-9
Author(s):  
Jian-hua Zhou ◽  
Hong-bo Shan ◽  
Wei Ou ◽  
Yun-xian Mo ◽  
Jin Xiang ◽  
...  
Keyword(s):  
Blood Flow ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Diagnostic Yield ◽  
Contrast Enhanced Ultrasound ◽  
Ultrasound Guided ◽  
Core Needle ◽  
Mediastinal Masses ◽  
Contrast Enhanced ◽  
Ancillary Studies

Based on the option that ultrasound-guided core needle biopsy (US-CNB) of the enhanced portion of anterior mediastinal masses (AMMs) identified by contrast-enhanced ultrasound (CEUS) would harvest viable tissue and benefit the histological diagnoses, a retrospective study was performed to elucidate the correlation between the prebiopsy CEUS and diagnostic yield of AMMs and found that CEUS potentially improved the diagnostic yield of AMMs compared with conventional US with a significant increase in the cellularity of samples. Furthermore, the marginal blood flow signals and absence of necrosis can predict the diagnostic yield of AMM. It was concluded that US-CNB of the viable part of AMMs, as verified by CEUS, was able to harvest sufficient tissue with more cellularity that could be used for ancillary studies and improve the diagnostic yield. And CEUS was recommended to those patients with AMMs undergoing repeated US-CNB, with the absence of marginal blood signals or presence of necrosis.

scholarly journals CT fluoroscopy-guided core needle biopsy of anterior mediastinal masses

2018 ◽  
Vol 99 (2) ◽  
pp. 91-97 ◽  
Author(s):  
T. Iguchi ◽  
T. Hiraki ◽  
Y. Matsui ◽  
H. Fujiwara ◽  
J. Sakurai ◽  
...  
Keyword(s):  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Ct Fluoroscopy ◽  
Core Needle ◽  
Mediastinal Masses

scholarly journals Accuracy and Safety of Ultrasound-Guided Core Needle Biopsy of Soft Tissue Tumors in an Outpatient Setting: A Sarcoma Center Analysis of 392 Consecutive Patients

Cancers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 5659
Author(s):  
Helene Weigl ◽  
Peter Hohenberger ◽  
Alexander Marx ◽  
Nikolaos Vassos ◽  
Jens Jakob ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Diagnostic Accuracy ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Outpatient Service ◽  
Outpatient Setting ◽  
Safe Procedure ◽  
Ultrasound Guided ◽  
Core Needle ◽  
Tertiary Referral Center

Background: The aim of this study was to investigate diagnostic accuracy, safety and histologic results of ultrasound guided core needle biopsy (CNB) in patients with soft tissue lesions (STL) at a tertiary referral center. Methods: A retrospective analysis of all consecutive patients undergoing ultrasound guided CNB for STL at our sarcoma outpatient service between January 2015 and August 2020 was performed. Results: A total of 392 patients were identified. Main histologic entities were sarcomas, lipomas and desmoid tumors. Biopsy was performed in an outpatient setting in 87.6% of the cases. Conclusive biopsies were obtained in 88.5% of the cases. In patients who underwent surgical resection after CNB, the concordance of dignity, tumor entity and histopathological grading between biopsy and resection specimen were 97.2%, 92.7% and 92.5% respectively. The risk of inconclusive CNB was highest in intraabdominal or retroperitoneal tumors (19.5%) and lowest in lesions at the lower extremity (4.4%). Major complications after CNB occurred in three cases (0.8%). No case of biopsy tract seeding was observed during the study period. Conclusions: Ultrasound guided CNB for STL at first presentation in a dedicated surgical outpatient setting is a safe procedure and yields a high diagnostic accuracy.

scholarly journals Diagnostic yield of percutaneous computed tomography guided core needle biopsy of lung lesion and its complications in tertiary hospital

2020 ◽  
Vol 8 (12) ◽  
pp. 4223
Author(s):  
Prakash Kayastha ◽  
Binaya Adhikari ◽  
Sundar Suwal ◽  
Benu Lohani ◽  
Sharma Paudel
Keyword(s):  
Computed Tomography ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Lung Biopsy ◽  
Diagnostic Yield ◽  
Lung Lesion ◽  
Ct Guided ◽  
Core Needle ◽  
Lung Lesions ◽  
Image Guided

Background: Early diagnosis of lung cancer can reduce its mortality and morbidity. Minimally invasive image guided percutaneous core needle biopsy can obtain tissue sample for diagnosis and staging of lung cancer, which is crucial for correct management of lung lesions. Common complications of lung biopsy include pneumothorax, parenchymal haemorrhage and haemoptysis. The study was aimed to determine diagnostic yield and complications of the percutaneous computed tomography (CT) guided core needle biopsy of lung lesion in tertiary hospital.Methods: Hospital based prospective study was performed in 40 patients in Tribhuvan University Teaching Hospital. CT guided biopsy of lung lesions was performed with 18-gauge semi-automated biopsy instrument. The complications following the biopsy were recorded and correlated with different factors using chi-square test. Histopathology report were obtained to measure the diagnostic yield.Results: Among 40 patients who underwent guided lung biopsy, histopathology showed definitive diagnosis in 37 patients; 31 malignant and 6 benign lesions. Parenchymal haemorrhage, pneumothorax and haemoptysis were seen in 13, 8 and 5 respectively; however, none required active intervention. Emphysema in traversing lung and numbers of pleural punctures used were predictive factors of complication (p value <0.05).Conclusions: The study showed percutaneous image guided core needle biopsy has high diagnostic yield with fewer complication rates and is thus recommended for routine biopsies of lung lesions.

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