scholarly journals Maclura tinctoria Extracts: In Vitro Antibacterial Activity against Aeromonas hydrophila and Sedative Effect in Rhamdia quelen

Fishes ◽  
2021 ◽  
Vol 6 (3) ◽  
pp. 25
Author(s):  
Luana da Costa Pires ◽  
Patricia Rodrigues ◽  
Quelen Iane Garlet ◽  
Luisa Barichello Barbosa ◽  
Bibiana Petri da Silveira ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Phenolic Compounds ◽  
Pathogenic Bacteria ◽  
Sedative Effect ◽  
In Vitro Antimicrobial Activity ◽  
Normal Behavior ◽  
In Vitro Antibacterial Activity ◽  
Light Sedation

Maclura tinctoria is a tree species native from Brazil and rich in phenolic compounds. Since plant antibacterial activity is highly associated with phenolic compound concentration, we aim to evaluate the in vitro antimicrobial activity of different extracts against fish pathogenic bacteria. In addition, some phenolic compounds have central depressant effects and can be useful in aquaculture due to possible sedative and/or anesthetic effects. Four M. tinctoria extracts were extracted separately with ethanol; leaves (LE), bark (BE), heartwood (HE), and the sapwood (SE). In vitro antimicrobial activity was tested against Aeromonas strains at concentrations of 6400 to 3.125 μg/mL. The sedative effect was evaluated for 24 h with 30 and 100 mg/L concentrations. Chemical composition was analyzed by HPLC-DAD-MS. The HE extract had the best MIC (400 µg/mL) and MBC (800 µg/mL) compared to the LE, BE, and SE extracts. LE extract induced deep sedation and the BE, SE, and HE extracts induced light sedation. Additionally, BE, SE, and HE induced a normal behavior without side effects. Polyphenolic compounds with antimicrobial activity and sedative effects were identified mainly in HE. Thus, HE extract is safe and can be used as a sedative for silver catfish.

scholarly journals In vivo and in vitro antibacterial activity of neomycin against plant pathogenic bacteria

2011 ◽  
Vol 6 (34) ◽  
pp. 6829-6834, ◽  
Author(s):  
Tao Ke ◽  
Fan Jieyu ◽  
Shi Guanying ◽  
Zhang Xingang ◽  
Zhao Haoyu ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Pathogenic Bacteria ◽  
Plant Pathogenic Bacteria ◽  
In Vitro Antibacterial Activity

scholarly journals Chemical characterization and in vitro antimicrobial activity of honeybee propolis and Scaptotrigona jujuyensis geopropolis against tomato pathogenic bacteria

2020 ◽  
Vol 42 (5) ◽  
pp. 1799-1808
Author(s):  
Irene Laura Cibanal ◽  
◽  
Leticia Andrea Fernández ◽  
Giovanni Galietta Positano ◽  
Lucía Bóffano Chebataroff ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Pathogenic Bacteria ◽  
Chemical Characterization ◽  
In Vitro Antimicrobial Activity

scholarly journals Synthesis and In Vitro Antibacterial Activity of Quaternized 10-Methoxycanthin-6-one Derivatives

Molecules ◽  
2019 ◽  
Vol 24 (8) ◽  
pp. 1553 ◽  
Author(s):  
Na Li ◽  
Dan Liu ◽  
Jiang-Kun Dai ◽  
Jin-Yi Wang ◽  
Jun-Ru Wang
Keyword(s):  
Antibacterial Activity ◽  
Seed Germination ◽  
Pathogenic Bacteria ◽  
Dilution Method ◽  
Highly Active ◽  
Structure Activity ◽  
In Vitro Antibacterial Activity ◽  
Potential Activity ◽  
Low Cytotoxicity

Background: Based on our previous work, we found that 10-methoxycanthin-6-one displayed potential antibacterial activity and quaternization was an available method for increasing the antibacterial activity. Here, we explored the antibacterial activity of quaternized 10-methoxy canthin-6-one derivatives. Methods and Results: Twenty-two new 3-N-benzylated 10-methoxy canthin-6-ones were designed and synthesized through quaternization reaction. The in vitro antibacterial activity against three bacteria was evaluated by the double dilution method. Moreover, the structure–activity relationships (SARs) were carefully summarized in order to guide the development of antibacterial canthin-6-one agents. Two highly active compounds (6p and 6t) displayed 8-fold superiority (MIC = 3.91 µg/mL) against agricultural pathogenic bacteria R. solanacearum and P. syringae compared to agrochemical streptomycin sulfate, and showed potential activity against B. cereus. Moreover, these two compounds exhibited good “drug-like” properties, low cytotoxicity, and no inhibition on seed germination. Conclusions: This work provides two new effective quaternized canthin-6-one derivatives as candidate bactericide, promoting the development of natural-sourced bactericides and preservatives.

scholarly journals In Vitro Antimicrobial Activity Evaluation of a Novel Fitostimoline® Plus Spray Formulation

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Maria Domenica Falciglia ◽  
Roberta Palladino ◽  
Barbara Maglione ◽  
Giulia Schiavo
Keyword(s):  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Standard Of Care ◽  
Microbial Infection ◽  
In Vitro Antimicrobial Activity ◽  
Disk Diffusion Assay ◽  
Spray Formulation ◽  
Carrier Test ◽  
And Control

Wound contaminants are the main cause of healing delay and infection in both chronic and acute wounds; for this reason, the microbial infection management in wound healing is one of the most important components for an effective standard of care. The wound contaminants are most likely to originate from the environment and from the surrounding skin lesion, and to date, the most frequent bacteria isolated are Staphylococcus aureus, Pseudomonas aeruginosa, and Klebsiella pneumoniae. In order to counteract and control these contaminants, the standard care includes topical antiseptic agents. The most commonly used include iodine-releasing agents (e.g., povidone-iodine), hydrogen peroxide, and polyhexanide. This study aims to investigate the in vitro antibacterial activity of a novel topical spray (Fitostimoline® Plus spray) based on 0.1% polyhexanide and Rigenase® against S. aureus, P. aeruginosa, K. pneumoniae, and the combination of S. aureus and K. pneumoniae. The in vitro antimicrobial activity of Fitostimoline® Plus spray was evaluated by the agar disk diffusion assay, quantitative suspension test, and quantitative carrier test, demonstrating that Fitostimoline® Plus spray is able to kill 99.9% bacteria. These results support the microbiological characterization of Fitostimoline® Plus spray confirming the antibacterial activity of polyhexanide (PHMB).

scholarly journals Synthesis and in vitro Antibacterial Activity of Quaternization 10-Methoxycanthin-6-one Derivatives

2019 ◽  
Author(s):  
Na Li ◽  
Jiang-Kun Dai ◽  
Dan Liu ◽  
Jin-Yi Wang ◽  
Jun-Ru Wang
Keyword(s):  
Antibacterial Activity ◽  
Natural Products ◽  
Minimum Inhibitory Concentration ◽  
Pathogenic Bacteria ◽  
Antibacterial Agents ◽  
Inhibitory Concentration ◽  
Dilution Method ◽  
In Vitro Antibacterial Activity

Natural products are an important source of antibacterial agents. Canthin-6-one alkaloids have displayed potential antibacterial activity based on our previous work. In order to improve the activity, twenty-two new 3-N-benzylated 10-methoxy canthin-6-ones were designed and synthesized through quaternization reaction. The in vitro antibacterial activity against three bacteria was evaluated by double dilution method. Four compounds (6f, 6i, 6p and 6t) displayed 2-fold superiority (minimum inhibitory concentration (MIC) = 3.91 µg/mL) against agricultural pathogenic bacteria R. solanacearum and P. syringae than agrochemical propineb. Moreover, the structure–activity relationships (SARs) were also carefully summarized in order to guide the development of antibacterial canthin-6-one agents.

scholarly journals In vitro antimicrobial activity of artemisia annua leaf extracts against pathogenic bacteria

2014 ◽  
Vol 6 ◽  
pp. 93-97 ◽  
Author(s):  
Ahmad Tajehmiri ◽  
Fahimeh Issapour ◽  
Mina Nasiri Moslem ◽  
Maryam Tavakoli Lakeh ◽  
Masoud Hassani Kolavani
Keyword(s):  
Antimicrobial Activity ◽  
Pathogenic Bacteria ◽  
Artemisia Annua ◽  
Leaf Extracts ◽  
In Vitro Antimicrobial Activity
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