scholarly journals Cancer Risks in Vitiligo Patients: A Nationwide Population-Based Study in Taiwan

2018 ◽  
Vol 15 (9) ◽  
pp. 1847 ◽  
Author(s):  
Cheng-Yuan Li ◽  
Ying-Xiu Dai ◽  
Yi-Ju Chen ◽  
Szu-Ying Chu ◽  
Tzeng-Ji Chen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prostate Cancer ◽  
Thyroid Cancer ◽  
Autoimmune Disease ◽  
Population Based ◽  
Research Database ◽  
Population Based Study ◽  
Male And Female ◽  
Female Patients ◽  
Male Patients

Vitiligo is an autoimmune disease characterized by destruction of melanocytes and associated with other autoimmune disease. Whether the dysregulation of immune system enhances oncogenesis or not remains obscure. Until now, no nationwide population-based study has been conducted regarding this. As such, this paper aims to clarify cancer risk in vitiligo patients. A retrospective nationwide population-based cohort study between 2000 and 2010 was performed based on data from the National Health Insurance Research Database of Taiwan. Standardized incidence ratios (SIRs) of cancers were analyzed. Among the 12,391 vitiligo patients (5364 males and 7027 females) and 48,531.09 person-years of observation, a total of 345 cancers were identified. Significantly increased SIRs were observed for prostate cancer in male patients, thyroid cancer and breast cancer in female patients and bladder cancers in both male and female patients. Unfortunately, the low incidence rate of certain cancers limited the power of our statistical analyses. This study demonstrated the patterns of malignancies in vitiligo patients of Taiwan. Compared with the general population, male patients had higher risks of prostate cancer and female patients had higher risks of thyroid cancer and breast cancer. The risks of bladder cancer were also increased in both male and female patients.

Second primary malignancies in gastric cancer: A U.S. population-based study.

2015 ◽  
Vol 33 (3_suppl) ◽  
pp. 191-191
Author(s):  
Binay Kumar Shah ◽  
Amit Khanal
Keyword(s):  
Breast Cancer ◽  
Prostate Cancer ◽  
Gastric Cancer ◽  
Thyroid Cancer ◽  
Myeloid Leukemia ◽  
Population Based ◽  
Second Primary ◽  
Population Based Study ◽  
Gastrointestinal Malignancies ◽  
Second Primary Malignancies

191 Background: Risk of second primary malignancies (SPM) is not known in gastric cancer. In this population based study, we analyzed rates of SPM in gastric cancer. Methods: We selected adult (≥18 years) patients with gastric cancer as first primary malignancy diagnosed from January 1992 to December 2011 from Surveillance, Epidemiology and End Result 13 database. We used SEER*stat’s multiple primary standardized incidence ratio (MP-SIR) session to calculate the risk of SPM diagnosed 6 months after the diagnosis of index gastric cancer. Results: Among 31,818 patients with first primary gastric cancer, 1674 (5.26%) developed 1,839 SPM with observed/expected (O/E) ratio of 1.09 (95% CI = 1.05-1.15, p<0.0001) and excess risk of 16.15 per 10,000 population. The median time to first SPM from the time of diagnosis of stomach cancer was 49 months (range 6 months to 19.08 years). There was significantly increased risk of gastrointestinal malignancies [O/E ratio 1.65 (CI=1.53-1.79, p<0.001)], thyroid cancer [O/E ratio 1.98 (CI=1.32-2.84, p<0.01)] and myeloid leukemia [O/E ratio 1.47(CI=1-2.09, p<0.05)]. Interestingly, there was significantly decreased risk of melanoma, breast cancer and prostate cancer. Conclusions: Our study showed that patients with gastric cancer are at higher risk of gastrointestinal malignancies, thyroid cancer and myeloid leukemia. Similarly, risk of melanoma, breast cancer and prostate cancer in patients with gastric cancer is lower than general population.

scholarly journals Incidence and Outcome of Male Breast Cancer: An International Population-Based Study

2011 ◽  
Vol 29 (33) ◽  
pp. 4381-4386 ◽  
Author(s):  
Hui Miao ◽  
Helena M. Verkooijen ◽  
Kee-Seng Chia ◽  
Christine Bouchardy ◽  
Eero Pukkala ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Male Breast Cancer ◽  
Relative Survival ◽  
Population Based ◽  
Male Breast ◽  
Survival Ratio ◽  
Population Based Study ◽  
Female Patients ◽  
Risk Of Death ◽  
Male Patients

Purpose Male breast cancer is a rare disease with an incidence rate less than 1% of that of female breast cancer. Given its low incidence, few studies have assessed risk and prognosis. Methods This population-based study, including 459,846 women and 2,665 men diagnosed with breast cancer in Denmark, Finland, Geneva, Norway, Singapore, and Sweden over the last 40 years, compares trends in incidence, relative survival, and relative excess mortality between the sexes. Results World standardized incidence rates of breast cancer were 66.7 per 105 person-years in women and 0.40 per 105 person-years in men. Women were diagnosed at a younger median age (61.7 years) than men (69.6 years). Male patients had a poorer 5-year relative survival ratio than women (0.72 [95% CI, 0.70 to 0.75] v 0.78 [95% CI, 0.78 to 0.78], respectively), corresponding to a relative excess risk (RER) of 1.27 (95% CI, 1.13 to 1.42). However, after adjustment for age and year of diagnosis, stage, and treatment, male patients had a significantly better relative survival from breast cancer than female patients (RER, 0.78; 95% CI, 0.62 to 0.97). Conclusion Male patients with breast cancer have later onset of disease and more advanced disease than female patients. Male patients with breast cancer have lower risk of death from breast cancer than comparable female patients.

Treatment Outcomes and Prognostic Factors in Male Patients With Stage IV Breast Cancer: A Population-based Study

2018 ◽  
Vol 18 (1) ◽  
pp. e97-e105 ◽  
Author(s):  
Wei Chen ◽  
Ying Huang ◽  
Gary D. Lewis ◽  
Sean S. Szeja ◽  
Sandra S. Hatch ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prognostic Factors ◽  
Treatment Outcomes ◽  
Stage Iv ◽  
Population Based ◽  
Population Based Study ◽  
Stage Iv Breast Cancer ◽  
Male Patients

scholarly journals Conditional Survival of female patients with operable invasive Breast Cancer in US: A population-based study

2020 ◽  
Vol 11 (19) ◽  
pp. 5782-5791
Author(s):  
Bolun Ai ◽  
Xiangyu Wang ◽  
Xiangyi Kong ◽  
Zhongzhao Wang ◽  
Yi Fang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Invasive Breast Cancer ◽  
Population Based ◽  
Conditional Survival ◽  
Population Based Study ◽  
Female Patients

Association of male breast cancer and prostate cancer: A large population based study.

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. 1541-1541
Author(s):  
Shaheenah S. Dawood ◽  
Joanne Ngeow Yuen Yie ◽  
Paul N. Mainwaring ◽  
Sudeep Gupta ◽  
Javier Cortes ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prostate Cancer ◽  
Male Breast Cancer ◽  
Large Population ◽  
Population Based ◽  
Male Breast ◽  
Population Based Study

scholarly journals Reinforcement of Tobacco Control and Reduction in Medical Utilization for Asthma in Taiwan: A Population-Based Study

2019 ◽  
Vol 16 (20) ◽  
pp. 3950
Author(s):  
Huang-Ju Liang ◽  
Ming-Jiuan Wu ◽  
Jih-Shuin Jerng ◽  
Chiang-Hsing Yang
Keyword(s):  
Subgroup Analysis ◽  
Population Based ◽  
Dust Storms ◽  
Medical Utilization ◽  
Smoking Ban ◽  
Utilization Rate ◽  
Research Database ◽  
Population Based Study ◽  
Male And Female ◽  
Prevention Act

Environmental air quality can affect asthma control and the development of overt asthmatic manifestations. In this population-based study, we investigated the effect of reinforcing a smoking ban in Taiwan through the enactment of the Tobacco Hazards and Prevention Act (THPA) on healthcare utilization rate by asthmatics. Analysis was performed based on data relevant to non-hospitalized asthmatic patients with insurance claims between 2005 and 2013 from the National Health Insurance Research Database of Taiwan, reported data on Asian dust storms, and penalty rates for violations of the tobacco ban. Poisson regression showed that the risk for outpatient visits for asthma was lower after enactment of the THPA (RR = 0.98, 95% CI = 0.98–0.99), with a yearly trend of a reduced risk (RR = 0.99, 95% CI = 0.99–1.00), also lower in geographic regions with medium (RR = 0.79, 95% CI = 0.79–0.80) and high (RR = 0.91, 95% CI = 0.91–0.92) penalty rates. Subgroup analysis showed that asthma visit rates were reduced in both male and female groups after the enactment of the THPA. The risk of an asthma ER visit was increased after the enactment of the amended THPA (RR = 1.07, 95% CI = 1.05–1.09), although the yearly trend was not significant (RR = 1.00, 95% CI = 1.00–1.00). The risk of emergency room visits for asthma was significantly reduced in regions with medium (RR = 0.68, 95% CI = 0.68–0.69) and high (RR = 0.75, 95% CI = 0.74–0.76) penalty rates. Subgroup analysis showed that the visit rates were similar in both male and female groups. The effectiveness of reinforcing the smoking ban warrants further policies aimed at further reducing passive smoking.

scholarly journals Medical Utilization of Emergency Departments among Patients with Prostate Cancer: A Nationwide Population-Based Study in Taiwan

2021 ◽  
Vol 18 (24) ◽  
pp. 13233
Author(s):  
Jui-Ming Liu ◽  
Ren-Jun Hsu ◽  
Yu-Tang Chen ◽  
Yueh-Ping Liu
Keyword(s):  
Prostate Cancer ◽  
Emergency Department ◽  
Emergency Departments ◽  
Population Based ◽  
Emergency Department Visits ◽  
Medical Expenditure ◽  
Medical Utilization ◽  
Common Disease ◽  
Research Database ◽  
Population Based Study

(1) Background: In Taiwan, prostate cancer is a major malignancy with an increasing incidence among men. This study explores the medical utilization of emergency departments among patients with prostate cancer in Taiwan. (2) Methods: This nationwide, population-based study was conducted via a cross-sectional method based on the Registry for Catastrophic Illness Patient Database from Taiwan’s National Health Insurance Research Database. Patients with newly diagnosed prostate cancer between 1997 and 2013 were enrolled in the study and divided into four treatment-related groups. The rate of emergency department presentation, disease categorization of emergency department visits, emergency department-related medical expenditures, and temporal trends were investigated. (3) Results: A total of 18,728 patients with prostate cancer were identified between 1997 and 2013, for whom 13,098 emergency department visits were recorded. The number of emergency department visits increased during the study period. The incidence rate for the medical utilization of emergency department visits was 822 per 1000 people during the study period. The incidence rates for patients with prostate cancer in the radical prostatectomy, radiotherapy, androgen deprivation therapy, and chemotherapy groups were 549, 1611, 1101, and 372, respectively. The average medical expenditure per emergency department visit was TWD 3779.8 ± 5116.2, and the expenditure was recorded for the chemotherapy group at TWD 4690.8 ± 7043.3. The most common disease diagnoses among patients with prostate cancer who presented to the emergency department were injury/poisoning (16.79%), genitourinary disorders (10.66%), and digestive disorders (10.48%). (4) Conclusions: This nationwide population-based study examined the emergency department visits of patients with prostate cancer in Taiwan, providing useful information for improving the quality of medical care.

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