scholarly journals A Multifactorial Evaluation of the Effects of Air Pollution and Meteorological Factors on Asthma Exacerbation

Author(s):  
Hong-Ren Yu ◽  
Chun-Hung Richard Lin ◽  
Jui-Hsiu Tsai ◽  
Yun-Ting Hsieh ◽  
Ti-An Tsai ◽  
...  

In the real world, dynamic changes in air pollutants and meteorological factors coexist simultaneously. Studies identifying the effects of individual pollutants on acute exacerbation (AE) of asthma may overlook the health effects of the overall combination. A comprehensive study examining the influence of air pollution and meteorological factors is required. Asthma AE data from emergency room visits were collected from the Taiwan National Health Insurance Research Database. Complete monitoring data for air pollutants (SO2; NO2; O3; CO; PM2.5; PM10) and meteorological factors were collected from the Environmental Protection Agency monitoring stations. A bi-directional case-crossover analysis was used to investigate the effects of air pollution and meteorological factors on asthma AE. Among age group divisions, a 1 °C temperature increase was a protective factor for asthma ER visits with OR = 0.981 (95% CI, 0.971–0.991) and 0.985 (95% CI, 0.975–0.994) for pediatric and adult patients, respectively. Children, especially younger females, are more susceptible to asthma AE due to the effects of outdoor air pollution than adults. Meteorological factors are important modulators for asthma AE in both asthmatic children and adults. When studying the effects of air pollution on asthma AE, meteorological factors should be considered.

2020 ◽  
Author(s):  
Hong-Ren Yu ◽  
Chun-Hung Richard Lin ◽  
Jui-Hsiu Tsai ◽  
Yun-Ting Hsieh ◽  
Ti-An Tsai ◽  
...  

Abstract Background: Study identify individual effect of single pollutants on asthma acute exacerbation (AE) may overlook the health effect of the mixture overall. In real world, dynamic changes of air pollutants and meteorologic factors coexist simultaneously. A comprehensive study was carried out to examine the influence of air pollution and meteorologic factors on asthma AE. Materials and methods: The asthma AE data from emergency room visits were collected from the Taiwan National Health Insurance Research Database from 2005 to 2013. Complete monitoring data for the air pollutants (sulfur dioxide, SO2; nitrogen dioxide, NO2; ozone, O3; carbon monoxide, CO; PM2.5; and PM10) and meteorologic factors (relative humidity, rainfall, and daily average temperature) were collected from Environmental Protection Agency monitoring stations. A bi-directional case-crossover analysis was used to investigate the effects of air pollution and meteorological factors on asthma exacerbation. Result: Along age group divisions, a 1 ℃ temperature increase was a protective factor for asthma ER visits, with OR = 0.981 (95% CI 0.971–0.991) and 0.985 (95% CI, 0.975–0.994) for pediatric and young adult patients, respectively. Each 1 mg/m3 increase in the 48-h averages of PM2.5 was associated with asthma ER visit for patients older than 65 years of age (OR = 1.008 (95% CI, 1.003–1.014). Conclusion: In Taiwan, asthma AE is closely related to low temperature and certain air pollution. Patients can take appropriate protective strategies to minimize risk of asthma AE related to air pollution/meteorological factors according to relevant gender and age.


Cephalalgia ◽  
2014 ◽  
Vol 34 (9) ◽  
pp. 656-663 ◽  
Author(s):  
Y-Jung Lee ◽  
Yung-Tai Chen ◽  
Shuo-Ming Ou ◽  
Szu-Yuan Li ◽  
Albert C Yang ◽  
...  

Background Cluster headache (CH) is well known to show a seasonal predilection; however, the impact of temperature and other meteorological factors on cluster periods (or bouts) has not been established. Methods This nationwide survey included 758 patients with episodic CH retrieved from the Taiwan National Health Insurance Research Database from 2005 to 2009. Corresponding meteorological recordings were obtained from the Central Weather Bureau. A case-crossover study design was used to investigate the association between cluster periods and meteorological factors. Results A total of 2452 episodes of cluster periods were recorded. The cluster periods were most frequent in the autumn and least frequent in the winter. Seasonal changes from winter to spring and from autumn to winter also increased the frequency of cluster periods. The risk of cluster periods increased when there was a higher mean temperature on event days (odds ratio (OR), 1.014, 95% confidence interval (CI), 1.005–1.023, p = 0.003) or within seven to 56 days. Either an increase or a decrease in temperature (0.05℃/day) following a warm period (mean temperature ≥26℃) was associated with the onset of cluster periods. In contrast, a greater increase in temperature (0.15℃/day) following a cold period (mean temperature < 21℃) was needed to evoke cluster periods. No such associations were found following moderate periods (21℃ ≤mean temperature <26℃). Discussion Our study shows that temperature is associated with precipitating or priming cluster periods. The influence depends on the temperature of the preceding periods.


Author(s):  
Han Cao ◽  
Bingxiao Li ◽  
Tianlun Gu ◽  
Xiaohui Liu ◽  
Kai Meng ◽  
...  

Evidence regarding the effects of environmental factors on COVID-19 transmission is mixed. We aimed to explore the associations of air pollutants and meteorological factors with COVID-19 confirmed cases during the outbreak period throughout China. The number of COVID-19 confirmed cases, air pollutant concentrations, and meteorological factors in China from January 25 to February 29, 2020, (36 days) were extracted from authoritative electronic databases. The associations were estimated for a single-day lag as well as moving averages lag using generalized additive mixed models. Region-specific analyses and meta-analysis were conducted in 5 selected regions from the north to south of China with diverse air pollution levels and weather conditions and sufficient sample size. Nonlinear concentration–response analyses were performed. An increase of each interquartile range in PM2.5, PM10, SO2, NO2, O3, and CO at lag4 corresponded to 1.40 (1.37–1.43), 1.35 (1.32–1.37), 1.01 (1.00–1.02), 1.08 (1.07–1.10), 1.28 (1.27–1.29), and 1.26 (1.24–1.28) ORs of daily new cases, respectively. For 1°C, 1%, and 1 m/s increase in temperature, relative humidity, and wind velocity, the ORs were 0.97 (0.97–0.98), 0.96 (0.96–0.97), and 0.94 (0.92–0.95), respectively. The estimates of PM2.5, PM10, NO2, and all meteorological factors remained significantly after meta-analysis for the five selected regions. The concentration–response relationships showed that higher concentrations of air pollutants and lower meteorological factors were associated with daily new cases increasing. Higher air pollutant concentrations and lower temperature, relative humidity and wind velocity may favor COVID-19 transmission. Controlling ambient air pollution, especially for PM2.5, PM10, NO2, may be an important component of reducing risk of COVID-19 infection. In addition, as winter months are arriving in China, the meteorological factors may play a negative role in prevention. Therefore, it is significant to implement the public health control measures persistently in case another possible pandemic.


Author(s):  
Shang-Shyue Tsai ◽  
Hui-Fen Chiu ◽  
Chun-Yuh Yang

Very few studies have been performed to determine whether there is a relationship between air pollution and increases in hospitalizations for peptic ulcer, and for those that have occurred, their results may not be completely relevant to Taiwan, where the mixture of ambient air pollutants differ. We performed a time-stratified case-crossover study to investigate the possible association between air pollutant levels and hospital admissions for peptic ulcer in Taipei, Taiwan. To do this, we collected air pollution data from Taiwan's Environmental Protection Agency and hospital admissions for peptic ulcer data for the years 2009–2013 from Taiwan's National Health Insurance's research database. We used conditional logistic regression to analyze the possible association between the two, taking temperature and relative humidity into account. Risk was expressed as odds ratios and significance was expressed with 95% confidence intervals. In our single pollutant model, peptic ulcer admissions were significantly associated with all pollutants (PM10, PM2.5, SO2, NO2, CO, and O3) on warm days (>23 °C). On cool days (<23 °C), peptic ulcer admissions were significantly associated with PM10, NO2, and O3. In our two-pollutant models, peptic ulcer admissions were significantly associated NO2 and O3 when combined with each of the other pollutants on warm days, and with PM10, NO2, and O3 on cool days. It was concluded that the likelihood of peptic ulcer hospitalizations in Taipei rose significantly with increases in air pollutants during the study period.


2020 ◽  
Vol 36 (1) ◽  
Author(s):  
Mai Hai Dang

Air pollution has been a growing concern for decades, which has a serious toxicological impact on human health and the environment. It has a number of different emission sources, but motor vehicles and industrial processes contribute the major part of air pollution. According to the World Health Organization, six major air pollutants include particle pollution, ground-level ozone, carbon monoxide, sulfur oxides, nitrogen oxides, and lead. Air pollution is considered as the major environmental risk factor in the incidence and progression of some diseases such as asthma, lung cancer, ventricular hypertrophy, Alzheimer's and Parkinson's diseases, psychological complications, autism, retinopathy, fetal growth, and low birth weight. This article aims to discuss toxicology of major air pollutants, sources of emission, and their impact on human health. We have also proposed practical measures to reduce air pollution in VietNam. Keywords: Air pollution, cardiovascular diseases, environment, human health, Vietnam. References: [1] http://www.healthdata.org/infograp hic/global-burden-air-pollution.[2] http://documents.worldbank.org/curated/en/781521473177013155/pdf/108141-REVISED-Cost-of-PollutionWebCORRECTEDfile.pdf.[3] https://epi.envirocenter.yale.edu/epi-topline.[4] https://thanhnien.vn/thoi-su/khong-khi-ha-noi-lai-vuon-len-muc-o-nhiem-nhat-the-gioi-1185769.html.[5] Convention on Long-Range Transboundary Air Pollution (adopted 13 November 1979, entered into force 16 March 1983).[6] United States Environmental Protection Agency (2007), “Terms of Environment: Glossary, Abbreviations and Acronyms.[7] Trường Đại học Luật Hà Nội, Giáo trình luật môi trường, NXB. Công an Nhân dân, Hà Nội, 2014, tr.165.[8] WHO, ‘A Global Assessment of Exposure and Burden of Disease: FAQs’ http://www. who.int/phe/health_topics/outdoorair/global-exposure-assessment-faq/en.[9] https://www.worldenvironmentday.global/what-causes-air-pollution#agriculture.[10] https://www.who.int/news-room/fact-sheets/detail/household-air-pollution-and-health.[11] WHO, “Household Air Pollution and Health” (February 2016).http://www.who.int/ mediacentre/factsheets/fs292/en/.[12] https://www.who.int/news-room/fact-sheets/detail/household-air-pollution-and-health.[13] M. Sand et al, “Response of Arctic Temperature to Changes in Emissions of Short-Lived Climate Forcers” (2016) 6 Nature Climate Change 286.[14] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862654/#B2-ijerph-16-04296.[15] https://www.sciencedirect.com/science/article/pii/S0269749114000062.[16] Kết luận số 56-KL/TW, ngày 23/8/2019 của Bộ Chính trị về tiếp tục thực hiện Nghị quyết Trung ương 7 khoá XI về chủ động ứng phó với biến đổi khí hậu, tăng cường quản lí tài nguyên và bảo vệ môi trường.[17] Quyết định số 79/QĐ-BTNMT, ngày 09/01/2020 của Bộ trưởng Bộ Tài nguyên và Môi trường về việc công bố 10 sự kiện ngành tài nguyên và môi trường năm 2019.[18] https://www.thiennhien.net/2020/02/25/chat-luong-khong-khi-do-thi-dien-bien-xau-trong-2-thang-dau-nam/.[19] https://vietnamnet.vn/vn/thoi-su/moi-truong/khong-khi-ha-noi-o-nguong-rat-co-hai-ngay-thu-7-lien-tiep-599095.html.[20] https://thanhnien.vn/thoi-su/khong-khi-ha-noi-lai-vuon-len-muc-o-nhiem-nhat-the-gioi-1185769.html.[21] Shannon N. Koplitz và cộng sự, Burden of Disease from Rising Coal-Fired Power Plant Emissions in Southeast Asia (2017), https://pubs.acs.org/doi/pdf/10.1021/acs.est.6b03731. [22] Nguyễn Quang Dy, Câu chuyện đầu năm: Nguy cơ khủng hoảng môi trường, http://www.viet-studies.net/kinhte/NQuangDy_KhungHoangMoiTruong.html.    


2018 ◽  
Vol 20 (3) ◽  
pp. 439-448

<p>Over the last few decades, the evidence on the adverse effects on the health of air pollution has been raised. Mortality is the most important health effect of ambient air pollution. We studied the relation between mortality and criteria pollutant air in Tehran, one of the highly industrialized, densely populated area and most polluted cities of the reign, during 2005-2014. For this purpose, we applied the approach proposed by the World Health Organization using the AirQ 2.2.3 model. Hourly concentrations of pollutants were taken from the Tehran environmental protection agency and Air Quality Control Company. In this model, the attributable proportion of health outcome, the annual number of excess cases of mortality for all causes were estimated. According to results, the number of total mortality caused by exposure to O3, NO2, SO2, PM10, PM2.5 in the past decade was 8042, 15141, 8136, 17776 and 20015 cases, respectively. The number of cumulative total mortality was 53110 cases in ten years. Furthermore, the number of cumulative cardiovascular and respiratory mortality 33887 and 8168 cases was estimated in last decade. A large number of residents of Tehran have died as a result of exposure to air pollutants; therefore for control and management of air pollution, appropriate actions on health and the environment should be performed.</p>


PeerJ ◽  
2019 ◽  
Vol 7 ◽  
pp. e6760 ◽  
Author(s):  
Lin-Shien Fu ◽  
Che-Chen Lin ◽  
Chia-Yi Wei ◽  
Ching-Heng Lin ◽  
Yung-Chieh Huang

Background Antipyretics are widely prescribed in pediatric practice. Some reports have mentioned that acetaminophen and non-steroid anti-inflammatory drugs may negatively affect asthma control by causing asthma exacerbation (AE). However, many confounding factors can also influence the risks. We assessed the impact of using acetaminophen or ibuprofen on AE in asthmatic children, especially those with strong risk factors. Methods We used the 2010 Taiwan National Health Insurance Research Database and identified 983 children with persistent asthma aged 1–5 years old; among them, 591 used acetaminophen alone and 392 used ibuprofen alone in 2010. Then, we analyzed the risk of AE over 52 weeks in the patients with and without severe AE in the previous year. Results The ibuprofen group had a higher risk of an emergency room (ER) visit or hospitalization for AE (odds ratio (OR) = 2.10, 95% confidence interval (CI) [1.17–3.76], P = 0.01). Among asthmatic children who had severe AE in the previous year, the risk of AE was higher in the ibuprofen group than in the acetaminophen group (OR = 3.28, 95% CI [1.30–8.29], P = 0.01), where as among those who did not, the risks of AE were similar between the acetaminophen and ibuprofen groups (OR = 1.52, 95% CI [0.71–3.25], P = 0.28). Conclusions Among young asthmatic children, use of ibuprofen was associated with a higher risk of AE than acetaminophen, if they had severe AE with ER visit or hospitalization in the previous year. Pediatricians should use antipyretics among children with asthma after a full evaluation of the risk.


Author(s):  
Meng-Chieh Chen ◽  
Chen-Feng Wang ◽  
Bo-Cheng Lai ◽  
Sun-Wung Hsieh ◽  
Szu-Chia Chen ◽  
...  

The issue of air pollution is gaining increasing attention worldwide, and mounting evidence has shown an association between air pollution and cognitive decline. The aim of this study was to investigate the relationships between air pollutants and cognitive impairment using the Mini-Mental State Exam (MMSE) and its sub-domains. In this study, we used data from the Taiwan Biobank combined with detailed daily data on air pollution. Cognitive function was assessed using the MMSE and its five subgroups of cognitive functioning. After multivariable linear regression analysis, a high level of particulate matter with an aerodynamic diameter of ≤2.5 μm (PM2.5), low ozone (O3), high carbon monoxide (CO), high sulfur dioxide (SO2), high nitric oxide (NO), high nitrogen dioxide (NO2), and high nitrogen oxide (NOx) were significantly associated with low total MMSE scores. Further, high SO2 and low O3 were significantly associated with low MMSE G1 scores. Low O3, high CO, high SO2, high NO2, and high NOx were significantly associated with low MMSE G4 scores, and high PM2.5, high particulate matter with an aerodynamic diameter of ≤10 μm (PM10), high SO2, high NO2, and high NOx were significantly associated with low MMSE G5 scores. Our results showed that exposure to different air pollutants may lead to general cognitive decline and impairment of specific domains of cognitive functioning, and O3 may be a protective factor. These findings may be helpful in the development of policies regarding the regulation of air pollution.


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