scholarly journals Human Health Risk Assessments of Trace Metals on the Clam Corbicula javanica in a Tropical River in Peninsular Malaysia

Author(s):  
Chee Kong Yap ◽  
Koe Wei Wong ◽  
Salman Abdo Al-Shami ◽  
Rosimah Nulit ◽  
Wan Hee Cheng ◽  
...  

This study aimed to analyse ten trace metal concentrations in the edible part of the freshwater clam Corbicula javanica and to provide a critical assessment of the potential risks to human health through consumption of this clam as food based on well-established indices and food safety guidelines. The clams were captured from a pristine original site and transplanted to other sites with different environmental qualities. The trace metal levels in the edible total soft tissue (TST) of the clam were below those of the food safety guidelines referred to except for Pb, which exceeded the permissible limit set by the European Commission (2006) and the US Food and Drug Administration/ Center for Food Safety and Applied Nutrition); Interstate Shellfish Sanitation Conference. (USFDA/CFSAN; ISSC) (2007). The estimated daily intake (EDI) values of the clam were found to be lower than the oral reference dose and the calculated target hazard quotient (THQ) and total THQ were found to be less than 1. Therefore, in conclusion, the human health risk for consumption of TST of C. javanica at both average and high-level were insignificant regardless of the environment it was exposed to.

2020 ◽  
Vol 14 ◽  
pp. 117863022091712
Author(s):  
Felly Esilaba ◽  
Wilkister Nyaora Moturi ◽  
Millicent Mokua ◽  
Terewe Mwanyika

The present study was conducted to determine daily intake of cadmium (Cd), copper (Cu), and lead (Pb) and to assess noncarcinogenic human health risk caused by these trace metals in the commonly consumed fish species ( Oreochromis niloticus, Rastrineobola argentea, Lates niloticus, and Protopterus aethiopicus) in Nakuru town, Kenya. Trace metal determination in the composite samples of the commonly consumed fish species was done using flame atomic absorption spectrophotometer. Cd, Cu, and Pb content in the muscle tissues of the commonly consumed fish species ranged from 0.11 ± 0.045 to 1.11 ± 0.931 mg kg−1 for Cd, 0.48 ± 0.013 to 3.00 ± 0.009 mg kg−1 for Cu, and 3.42 ± 0.045 to 12.78 ± 0.108 mg kg−1 for Pb. Cu concentrations were within Food and Agriculture Organization (FAO) recommended limits for this trace metal in fish. In contrast, Cd and Pb had values above their respective permissible limits in fish. The assessment of human exposure to trace metals indicated that exposure doses of Cd and Cu were safe for fish consumers. Conversely, target hazard quotient (THQ) values of Pb suggested possible health risks for consumers of the commonly consumed fish species in Nakuru town, Kenya.


2021 ◽  
Vol 37 (2) ◽  
pp. 419-425
Author(s):  
G. M. M. Anwarul Hasan ◽  
Sanjida Khanam

Heavy metal mediated toxicity is associated with several health risks. In this research, heavy metal contents in selected dairy products such as Cheese, Ghee (Local processed dairy product) and Butter were determined and studied their effects on human health. From the results, it was determined that, Cu had the highest concentration and daily intake rate in Cheese, Ghee and Butter samples; while Pb had the lowest concentration and daily intake rate in Cheese and Butter samples. The estimated daily intake (EDI) values of all these metals were less than the permissible value. Also the results of THQ (Target hazard quotient), TTHQ (Total target hazard quotient) and TCR (Target Carcinogenic risk)suggested that, all of these values of these dairy product samples were less than the risk value. Our current study indicated that there is no chance of any kind of health risk through the consumption of these dairy products.


2021 ◽  
Author(s):  
Md. Monirul Islam ◽  
Nusrat Jahan Avha ◽  
Shamim Ahmed ◽  
Md. Ahedul Akbor ◽  
Md. Sofiqul Islam ◽  
...  

Abstract Substantial quantity of fish has been imported to Bangladesh without adequate food safety assessment which can pose a serious health risk to local people. This study analyzed the trace metals and organochlorine pesticides residues and the associated human health risk in 33 imported fishes (9 species) from four countries (India, Myanmar, Oman and United Arab Emirates) collected from three different ports (Benapole, Bhomra, and Chittagong) of Bangladesh with invoice lists from the port authorities. Trace metal concentrations were determined using graphite furnace absorption spectrometry and flame absorption spectrometry. The two organochlorine pesticides (Aldrin and Chlordane) residues were determined by GC-MS and found as below detection level (BDL). The trace metal concentrations (mg/kg-ww) in imported fish samples ranged as: As: 0.008 to 0.558; Pb: 0.004 to 0.070; Cr: 0.010 to 0.109; Cd: 0.00 to 0.083; Ni: 0.011 to 0.059; Co: BDL to 0.067; Mn: BDL to 0.0780; Fe: 1.780 to 10.77; Cu: 0.055 to 0.632; and Zn: 0.898 to 9.245. Concentrations of As and Cd were higher than the food safety guideline. Considering the source country of imported fishes, fish samples from Oman were mostly contaminated by the trace metals. The estimated daily intake (EDI) was higher for As and Cr. However, the target hazard quotient (THQ) for individual metal and total THQ for combined metals were lower than 1, indicating no apparent non-carcinogenic health risk for consumers. But target cancer risk (TR) was higher for As, and Ni and the values exceeded the acceptable range indicating a high carcinogenic risk for the local people. Therefore, extensive monitoring of these toxic chemicals is needed prior to import these fishes to the country. Given the self-sufficiency in fish production this study also argues whether Bangladesh needs to import the fishes at all.


Author(s):  
I. Felagha ◽  
M. O. Monanu ◽  
B. A. Amadi

Heavy metals pose a threat to human health and their presence in specific matrices is anthropogenic. The work focuses on the penetration of the food chain through the ingestion of mollusk proteins. This study evaluated the composition of heavy metals (Cd, Cr, Mn, Pb and Zn) in three species of mollusks (Limicolaria flammea, Viviparus contectus, Egeria radiata) from Yenagoa, Bayelsa State, Nigeria and the health risk associated with their consumption. Heavy metals concentration was determined by Atomic Absorption Spectrophotometer (AAS). Health risk associated with consumption of the samples were assessed by Estimated Daily Intake (EDI), target Hazard Quotient (THQ) and Carcinogenic Risk (CR). EDI, THQ and CR were done by calculation following standards. Heavy metals concentration range in the samples were: Cd (0.289±0.00 mg/kg - 0.667±0.00 mg/kg), Mn (0.816±0.00 mg/kg - 0.934±0.00 mg/kg), Pb (0.082±0.00 mg/kg - 0.092±0.00 mg/kg) and Zn (4.114±0.00 mg/kg - 8.534±0.00 mg/kg); Cr was not detected in neither of the samples.  EDI of heavy metals through consumption of these samples were within acceptable limits for all heavy metals detected. THQ ranges were as follows: Cd (0.4949-1.1420), Mn (0.000017-0.000019), Pb (0.0401 - 0.0450) and Zn (0.0016 - 0.0066).  THQ values indicate that there is no human risk concern of risk for humans except Cd (in E. radiata). CR values for Cd were as follows: L. flammea (3.8×10-3), E. radiata (4.34×10-4) and V. contectus (1.88×10-4). CR values were within acceptable limits with the exception of Cd in L. flammea. The present study shows that the samples contained detectable levels of heavy metals however their consumption do not pose any form of health risk with the except for Cd in L. flammea, hence the carcinogenic role of L. flammea stands out for its high content of Cd.


Author(s):  
Chee Kong Yap ◽  
Azlini Razali ◽  
Rosimah Nulit ◽  
Shih Hao Tony Peng ◽  
Chee Wah Yap ◽  
...  

This study aimed to investigate the concentrations of copper (Cu), zinc (Zn), nickel (Ni), lead (Pb) and iron (Fe) in different parts of guava (pulps, peels and seeds) and its topsoil collected from Kluang, Malaysia, and to assess their effects on human health. The level of metals was determined using acid digestion method and atomic absorption spectrometry. The result showed that the concentrations of Cu, Zn and Pb in all parts of guava were above the World Health Organization (WHO) permissible limits. However, the value of heavy metals in the topsoil were below the WHO limit. The concentration order of the metals in the guava's pulps was Fe > Cu > Zn > Pb > Ni. The contamination factor (Cf ) calculated from the topsoil were low for Cu, Zn and Ni and moderate for Pb. However, potential ecological risk (Er) of individual metal ranged from 0.25-7.58 for Cu, Zn, Pb and Ni was low. The potential non-carcinogenic health risk for consumers was assessed using estimated daily intake (EDI) and target hazard quotient (THQ). The contribution of heavy metals to the EDI for all consumers followed the order of Fe > Cu > Zn > Pb > Ni. The THQ values are all below 1 for all five metals tested, indicating no potential risk to the consumers. We suggest that the Kluang's guava is safe to consume. However, regular monitoring and human health risk assessment of heavy metals in the guava is recommended to be carried out.


Author(s):  
Chima Fausta Nnodum ◽  
Kafeelah Abosede Yusuf ◽  
Comfort Adetutu Adeniji

Abstract: Introduction : Heavy metals are known to cause deleterious effects on human health through food chain. Aims: The study is aimed at assessing heavy metal concentrations in the tissues of four highly consumed fish species and to evaluate the potential health risks associated with their consumption. Materials and Methods: The concentrations of Cu, Cd and Pb were analyzed in the tissues of Titus (Scomber Japonicus), Croaker (Pseudolithus Elongatus), Scumbia (Ilisha Africana) and Shrimps (Pipeus Notialis) by atomic absorption spectrophotometry (AAS) after digestion of the samples. Results: The results showed that Cd was not detected in the tissues of all fish species. There were variations among Cu and Pb concentrations in the tissues of the fish species. Cu had the highest concentrations (1.00 µg/g) in the tissues of croaker and shrimps respectively while Pb had the lowest concentrations (0.25 µg/g) in the tissues of Scumbia . The levels of all metals in the present study were lower than the limits permitted by Food and Agriculture Organization of the United Nations/World Health Organization (FAO/WHO), European Community Regulation (EU) and European Commission (EC). Assessment of noncarcinogenic health hazard using Target hazard quotient (THQ) and hazard index (HI) indicated no concern from consumption of these fish species. The estimated daily intake (EDI) of the studied metals through fish consumption was below the permissible tolerable daily intake. Conclusion: It can be concluded that there is no potential human health risk from consumption of the selected fish species. Keywords: Heavy metals, Hazard index, Target hazard quotient.


Biologija ◽  
2019 ◽  
Vol 65 (3) ◽  
Author(s):  
Ijeoma Patience Oboh ◽  
Benjamin Chima Okpara

Consumption of fish is a primary route of exposure to heavy metals that could be detrimental to human health due to the tendency of bioaccumulation and biomagnification along the food chain. The aim of this study was to evaluate the accumulation of heavy metals (Ni, Zn, Pb, Fe, and Cr) in two commercially available fishes, Clarias gariepinus and Parachanna obscura, and to estimate the health risks they pose to humans through consumption. Twenty-four (24) fish samples (triplicates for each month for the two species) were collected between July and October 2017. Heavy metals were identified using the atomic absorption spectrophotometer and the health risk to consumers was evaluated using Estimated Daily Intake (EDI), the Target Hazard Quotient (THQ), and the Hazard Index (HI). The THQ for the individual metals in C. gariepinus and P. obscura occurred in the decreasing order of Cr > Pb > Ni and Cr > Pb > Ni > Fe with risk values of 0.015, 0.004, and 0.001, and 0.014, 0.010, 0.002, and 0.001, respectively. The hazard index for C. gariepinus and P. obscura were 0.021 and 0.027, respectively. The values of the hazard index values of the two fish species were below the threshold value of 1, an indication of no potential health risk to consumers of the fishes. However, with the occurrence of bioaccumulation of metals in the studied fishes, regular monitoring of the river is recommended.


Author(s):  
Ajeng Kurniasari Putri ◽  
Giri Rohmad Barokah ◽  
Nuri Andarwulan

Aquatic environment of Jakarta Bay have already been highlighted due to its heavy metals contamination which may lead into food safety concern of fisheries products derived from this region. This research aimed to investigate bioaccumulation level of heavy metals (Pb, Cd, and As) in fish and mussels from Jakarta Bay, as a human risk assessment of seafood consumption. Samples of mussels and fish were taken from Penjaringan, Tarumanegara, Cilincing, and Tanjung Pasir district. Bioaccumulation of heavy metals was analyzed by Inductively Coupled Plasma -Mass Spectrometry technique. Results of the study revealed that metals bioaccumulation in fisheries products were varied, with As (Arsenic) as the highest metal contaminant (0.68 mg/kg, dry weight). Furthermore, estimated daily intake (EDI), target hazard quotient (THQ), total target hazard quotient (TTHQ), and safety limits prescribed by various agencies, showed that consumption of fisheries products from Jakarta Bay considered as relatively safe for human health in total of food ingestion rate of fish 57.34 g/day. These results are expected to serve as a baseline to construct preventive and palliative policies for food safety of fisheries products from Jakarta Bay.


2021 ◽  
Author(s):  
Tasneem Sarwar ◽  
Sardar Khan ◽  
Said Muhammad ◽  
Javed Nawab ◽  
Shehla Amin ◽  
...  

Abstract Arsenic (As) is one of the toxic metalloids therefore can cause health risk in the consumers through consumption of contaminated food and rice. The current study focused on As speciation in rice, bioavailability, mechanisms and its potential human health risk. For this purpose, rice and soil samples were collected from 16 different districts (non-mining and mining) of Khyber Pakhtunkhwa (Pakistan). Soil physicochemical characteristic such as texture, electrical conductivity (EC), organic matter (OM), pH, iron (Fe) and phosphorus (P) were determined. Total arsenic (AsT) concentrations were analyzed using ICP-MS, while the arsenite (As3+), arsenate (As5+), arsenobetine (BAs), dimethylarsenic (DMA) and monomethyl arsenic (MMA) were determined by HPLC–ICP-MS method. Results showed the highest AsT (0.28 mg/kg) was observed in the rice samples of DI Khan District and lowest (0.06 mg/kg) in Shangla District. However, these findings were found within the permissible limits set by various authorities. Furthermore, results showed higher concentrations of inorganic As (Asi) than organic As (Aso) species in rice. The estimated daily intake (EDI) and incremental lifetime cancer risk (ILTCR) were used to evaluate the potential human health risk for As consumption in rice. Results revealed that the rice samples collected from the district having mining activities had higher value of As (0.28 mg/kg of AsT) as compared to non-mining (0.072 mg/kg of AsT). The highest ILTCR value (0.00196) was observed for rice collected from mining districts. This study revealed that mining activities have great influence on the As contamination of soil and grown rice. This study recommends the soil amendment in districts having mining activities to lower As availability in soil and its bioaccumulation in growing rice that will help to keep lower the potential risk.


2018 ◽  
Vol 29 (1) ◽  
pp. 8-24 ◽  
Author(s):  
Uchechi Bliss Onyedikachi ◽  
Donatus Chuka Belonwu ◽  
Mattew Owhonda Wegwu

Abstract In view of ensuring healthy agricultural foods for human consumption, this study assessed the human health risk implicated in selected heavy metals in some commonly consumed vegetables, tubers, nuts and fruits grown around the quarry sites at Ishiagu, Ebonyi State, Nigeria. Samples from agriculture area of Umudike, Abia State, Nigeria, constituted the control. The concentration of Mn, Zn, Fe, Cu, Cd, and Pb, were determined using atomic absorption spectrometry. The potential non-carcinogenic health risk for consumers which included Estimated Daily Intake (EDI) and Target Hazard Quotients (THQ) for Pb, Fe, Mn, Zn, Cd and Cu while carcinogenic health risk using Cancer Slope Factors (CSF) was established for Cd and Pb. Relative abundance of heavy metals across the locations and all samples was in the order Fe > Mn > Zn > Pb > Cu > Cd. There was statistical significant effect of quarrying activities on the concentration of the heavy metals (Fe, Mn, Zn, Pb, Cu, Cd) at p < 0.05 level. Based on the observed bioconcentration factors, cassava showed more hyperaccumulation potential compared to other samples. Pumpkin and bitter leaf also could be used in remediation owing to their high bioaccumulation index for Pb and Zn. THQ obtained for Mn and Pb were >1 indicating that the residents at the quarry site may be exposed to potential non-carcinogenic health risk due to Mn and Pb intoxication. With respect to US EPA prescriptions, average carcinogenic risk values obtained for Pb and Cd in this study indicated a lifetime (70 years) probability of contracting cancer suggesting that they be placed for further consideration as chemicals of concern with respect to the assessed locals.


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