scholarly journals Economic Burden of Depressive Symptoms Conditions among Middle-Aged and Elderly People with Hypertension in China

2021 ◽  
Vol 18 (19) ◽  
pp. 10009
Author(s):  
Yun Wu ◽  
Dongbao Zhao ◽  
Jianwei Guo ◽  
Yingsi Lai ◽  
Lijin Chen ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Economic Burden ◽  
Mental Healthcare ◽  
Economic Loss ◽  
Healthcare Services ◽  
Middle Aged ◽  
Hypertensive Patients ◽  
Multivariable Regression ◽  
Elderly Hypertensive ◽  
Healthy Functioning

People with hypertension are more prone to incur depressive symptoms, while depressive symptoms have an obvious influence on the healthy functioning, treatment, and management of hypertensive patients. However, there have been limited studies on the association between depression and the economic burden of hypertension. We used data from the 2018 China Health and Retirement Longitudinal Study (CHARLS) to estimate the additional annual direct and indirect economic burden of depressive symptoms among middle-aged and elderly hypertensive patients with a multivariable regression model. The depressive symptoms were associated with substantial additional direct and indirect economic burden. Compared with non-co-MHDS (non-co-morbid hypertension and depressive symptoms) patients, the direct economic burden of lower co-MHDS (co-morbid hypertension and depressive symptoms) patients and higher co-MHDS patients increased 1887.4 CNY and 5508.4 CNY, respectively. For indirect economic burden, the lower co-MHDS patients increased 331.2 CNY and the higher co-MHDS patients increased 636.8 CNY. Both direct and indirect economic burden were incremental with the aggravation of depressive symptoms. The results showed depressive symptoms increased total healthcare costs by increasing the utilization and expenditure of primary healthcare services. Depressive symptoms also led to economic loss of productivity, especially for agricultural workers. This study highlights the importance of mental healthcare for hypertensive patients.

scholarly journals STATE OF THE PLATELET HEMOSTASIS IN THE MIDDLE-AGED AND THE ELDERLY HYPERTENSIVE PATIENTS

2020 ◽  
Vol 2 (12) ◽  
pp. 120-125
Author(s):  
V. S. Pasko
Keyword(s):  
Essential Hypertension ◽  
Elderly Patients ◽  
The Elderly ◽  
Control Group ◽  
Middle Aged ◽  
Hypertensive Patients ◽  
Group I ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients ◽  
Induced Aggregation

It has long been known that complications of essential hypertension are associated mostly with disorders of blood coagulation system and degree of absolute risk of cardiovascular events is growing with increasing of age. That is why much attention is paid to more detailed study of mechanisms of thrombosis as the component of complications of essential hypertension through lens of hemostatic changes at present. Therefore, regulatory mechanisms of initiation of thrombus formation and participation of platelet hemostasis are studied in hypertensive patients insufficiently today. The aim of the study was to identify the baseline levels of the platelet hemostasis indices in the middle-aged and the elderly hypertensive patients. Material and methods. We performed the comparative assessment of status of the platelet hemostasis in 63 middle-aged (group I) and 53 elderly patients (group II) respectively to clarify this issue in our work. Patients of the surveyed groups were comparable in age, sex and related pathology. The control group consisted of 15 patients for every of the surveyed groups (group III the middle-aged and group IV the elderly respectively) matched with basic by age and gender. Conclusions. Therefore, there is the increase in platelet activity depending on age in the middle-aged and the elderly hypertensive patients that is manifested by adrenaline stimulation most clearly. In addition, the most significant changes are determined in the spontaneous and the adrenaline-induced aggregation namely in amplitude and slope of aggregation in the spontaneous and time of maximal aggregation in the adrenaline-induced aggregation in the patients of older age group compared with the middle-aged patients. The substantial deceleration of time of maximal aggregation during the adrenaline stimulated aggregation in 1,6 times (p<0,001) in the elderly patients confirms the expressed thrombogenicity and sensitiveness to neurohumoral influences too. Thus, the blood plasma thrombogenicity revealed in the study of the platelet hemostasis in the elderly indicates a high probability of thrombotic complications developing in this category of the patients and this is consistent with literature.

scholarly journals Mathematical evaluation of 24-hour blood-pressure variability in young, middle-aged and elderly hypertensive patients.

1987 ◽  
Vol 51 (10) ◽  
pp. 1123-1130 ◽  
Author(s):  
OSAMU TOCHIKUBO ◽  
NAOMICHI MIYAZAKI ◽  
YUTAKA YAMADA ◽  
MASAKAZU FUKUOKA ◽  
YOSHIHIRO KANEKO
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Variability ◽  
Middle Aged ◽  
Hypertensive Patients ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients ◽  
Mathematical Evaluation

scholarly journals RELATIONSHIP BETWEEN OBESITY AND COGNITIVE FUNCTION IN MIDDLE-AGED AND ELDERLY HYPERTENSIVE PATIENTS

2019 ◽  
Vol 37 ◽  
pp. e275
Author(s):  
T. Pál ◽  
M. Germán-Salló ◽  
E. Nemes-Nagy ◽  
B. Baróti ◽  
R.G. Tripon ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Middle Aged ◽  
Hypertensive Patients ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients

Studies on the Renin-Angiotensin-Aldosterone System in Elderly Hypertensive Patients with an Angiotensin II Antagonist

1979 ◽  
Vol 57 (5) ◽  
pp. 461-463 ◽  
Author(s):  
T. Ogihara ◽  
T. Hata ◽  
Anna Maruyama ◽  
H. Mikami ◽  
M. Nakamaru ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
The Elderly ◽  
Middle Aged ◽  
Renin Angiotensin Aldosterone System ◽  
Plasma Aldosterone Concentration ◽  
Hypertensive Patients ◽  
Renin Angiotensin ◽  
Angiotensin Ii Antagonist ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients

1. To characterize the renin-angiotensin-aldosterone system in elderly hypertensive patients, an angiotensin II antagonist, [Sar1,Ile8]angiotensin II, was infused into individuals 60 years old and older with and without hypertension. 2. After infusion of [Sar1,Ile8]angiotensin II in all of the elderly patients and subjects an agonistic pressor response was observed that was greater than in middle-aged hypertensive patients. 3. Pre-infusion plasma renin activity and plasma aldosterone concentration in hypertensive and normotensive elderly groups were suppressed in comparison with those in middle-aged hypertensive subjects. The increased agonistic effects of [Sar1,Ile8]angiotensin II infusion on blood pressure in the elderly are presumably due to their hyporeninaemia. 4. The angiotensin-aldosterone system in elderly essential hypertensive patients is suppressed and is presumably not responsible for their elevated blood pressures.

The Effect of Prophylactic Ephedrine on Systemic Hypotension Caused by Induction of Anaesthesia with Propofol and Sufentanil in Elderly Hypertensive Patients: A Prospective Randomized, Double-blind Placebo-controlled Clinical Trial

2020 ◽  
Keyword(s):  
Blood Pressure ◽  
General Anesthesia ◽  
Normal Saline ◽  
Saline Group ◽  
Normal Saline Group ◽  
Hypertensive Patients ◽  
Group A ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients ◽  
Group B

Objective: To study the effectiveness of prophylactic ephedrine to prevent hypotension caused by induction of anesthesia with propofol and sufentanil in elderly hypertensive patients. Methodology: 70 elderly ASA grade II-III hypertensive patients undergoing elective general anesthesia were randomized into two groups to receive either intravenous ephedrine,100 ug/kg in 5ml normal saline (Group B), or an equal volume of normal saline (Group A) before induction. Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP) and Heart Rate (HR) were recorded at T0 (after entry to the operating room), T1 (1 min after induction), T2 (2 min after induction), T3 ( 3 min after induction), T4 (4 min after induction), T5 (when intubated), T6 (2 min after intubation), and T7 (at the start of the procedure), as well as the incidence of hypotension and bradycardia. Results: SBP, DBP and HR were not significantly different at T0 and were significantly different at T1 to T7 after anesthesia induction. There were statistically significant effect on hypotension and bradycardia between the two groups and group B have a lower risk of hypotension and bradycardia relative to group A. SBP and DBP decreased significantly after induction in both groups. HR decreased significantly in group A while increased in group B. Conclusion: Ephedrine pretreatment can minimize hypotension and bradycardia caused by propofol and sufentanil during the induction of general anesthesia in elderly patients with hypertension.

Nocturnal Fall of Blood Pressure and Silent Cerebrovascular Damage in Elderly Hypertensive Patients

Hypertension ◽  
1996 ◽  
Vol 27 (1) ◽  
pp. 130-135 ◽  
Author(s):  
Kazuomi Kario ◽  
Takefumi Matsuo ◽  
Hiroko Kobayashi ◽  
Masahiro Imiya ◽  
Miyako Matsuo ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Hypertensive Patients ◽  
Elderly Hypertensive ◽  
Elderly Hypertensive Patients

scholarly journals Association between socioeconomic status and longitudinal sleep quality patterns mediated by depressive symptoms

SLEEP ◽  
2021 ◽  
Author(s):  
Ga Bin Lee ◽  
Hyeon Chang Kim ◽  
Ye Jin Jeon ◽  
Sun Jae Jung
Keyword(s):  
Socioeconomic Status ◽  
Depressive Symptoms ◽  
Sleep Quality ◽  
Household Income ◽  
Pittsburgh Sleep Quality Index ◽  
Multinomial Logistic Regression ◽  
Mental Healthcare ◽  
Mediation Effect ◽  
Multinomial Logistic Regression Model ◽  
Mediating Role

Abstract Study Objectives We aimed to examine whether associations between socioeconomic status (SES) and longitudinal sleep quality patterns are mediated by depressive symptoms. Methods We utilized data on 3347 participants in the Korean Genome and Epidemiology Study aged 40–69 years at baseline from 2001 to 2002 who were followed up for 16 years. A group-based modeling approach was used to identify sleep quality trajectories using the Pittsburgh Sleep Quality Index (years 2, 6, 8, 10, and 12). Educational attainment (college graduated or less), monthly household income (≥$2500 or less), and occupation (unemployed, manual labor, and professional labor) at baseline (year 0) were used for analyses. Depressive symptoms were assessed using Beck’s Depression Inventory at year 4. Associations between SES and sleep quality patterns were examined using a multinomial logistic regression model. The mediation effect of depressive symptoms was further examined using PROC CAUSALMED. Results We identified five distinct sleep quality trajectories: “normal-stable” (n = 1697), “moderate-stable” (n = 1157), “poor-stable” (n = 320), “developing to poor” (n = 84), and “severely poor-stable” (n = 89). Overall, associations between SES levels and longitudinal sleep patterns were not apparent after full adjustment for sociodemographic and lifestyle factors measured at baseline. Depressive symptoms, however, tended to fully mediate associations between SES levels and sleep quality patterns (odds ratio range for indirect effects of depressive symptoms: for education, 1.05-1.17; for income, 1.05-1.15). Conclusion A significant mediating role for depressive symptoms between SES levels and longitudinal sleep quality warrants consideration among mental healthcare professionals.

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