scholarly journals The Impact of Hypertension, Diabetes, Lipid Disorders, Overweight/Obesity and Nicotine Dependence on Health-Related Quality of Life and Psoriasis Severity in Psoriatic Patients Receiving Systemic Conventional and Biological Treatment

Author(s):  
Anna Karpińska-Mirecka ◽  
Joanna Bartosińska ◽  
Dorota Krasowska

Psoriasis, a chronic disease, is associated with a higher prevalence of comorbidities and has negative impact on health-related quality of life (HRQOL). The objective was to investigate the effect of comorbidities on HRQOL, and psoriasis severity measured appropriately by the dermatology life quality index (DLQI) and the psoriasis area severity index (PASI) before, and after a 3-month treatment and the median DLQI or PASI reduction from baseline in the adult psoriatic patients receiving various types of treatment. The study included 184 adult plaque psoriatic patients. DLQI and PASI scores were assessed in the studied patients before the therapy (a baseline visit) and after a 3-month treatment (a control visit) depending on the presence of comorbidities. Psoriatic patients with comorbidities had worse HRQOL and more severe skin lesions. The presence of comorbidities had a negative effect on the outcome of treatment with the use of conventional therapy. The outcome of therapy with biological agents was independent of each of the analyzed factors. Biological treatment had a high effectiveness on the psoriatic skin lesions improvement despite the presence of comorbidities, whereas methotrexate was effective even if the patients had co-existing hypertension. In psoriatic patients receiving systemic conventional treatment but not biological treatment, comorbidities had a negative impact on HRQOL and psoriasis severity.

2014 ◽  
Vol 85 (6) ◽  
pp. 986-991 ◽  
Author(s):  
Mu Chen ◽  
Zhi-Cai Feng ◽  
Xue Liu ◽  
Zheng-Ming Li ◽  
Bin Cai ◽  
...  

ABSTRACT Objective:  To assess oral health–related quality of life (OHRQoL) in young adult patients with malocclusion and to measure the association between orthodontic treatment need and OHRQoL. Materials and Methods:  The study sample comprised 190 young adults aged 18 to 25 years who were attending orthodontic clinics at the Faculty of Dentistry. The Index of Orthodontic Treatment Need-Dental Health Component was used to measure orthodontic treatment need. Each participant was assessed for OHRQoL before and after treatment by using the Oral Health Impact Profile, Chinese version (OHIP-14). Results:  Patients who had little or no, borderline, and actual need for orthodontic treatment represented 21.6%, 50.5%, and 27.9% of the total sample, respectively. OHRQoL (total OHIP-14 score and score for each domain) improved after treatment (P < .05). Significant differences in summary OHIP-14 scores were apparent with respect to orthodontic treatment need. Participants with high treatment need reported a significantly greater negative impact on the overall OHRQoL score. The greatest impact was seen in the psychological discomfort domain and the psychological disability domain. Conclusion:  Malocclusion has a significant negative impact on OHRQoL. This is greatest for the psychological discomfort and psychological disability domains. The orthodontic treatment of malocclusion improves OHRQoL of patients.


2018 ◽  
Vol 52 (6) ◽  
pp. 570-579 ◽  
Author(s):  
Ana Flávia Granville-Garcia ◽  
Monalisa Cesarino Gomes ◽  
Matheus França Perazzo ◽  
Carolina Castro Martins ◽  
Mauro Henrique Nogueira Guimarães Abreu ◽  
...  

The aim of the present study was to evaluate the influence of the severity/activity of dental caries as well as sense of coherence (SOC) and locus of control (LOC) on oral health-related quality of life (OHRQoL) among 5-year-old children. A cross-sectional study was conducted involving 769 children at schools in a city in northeast Brazil. Parents/caregivers answered validated questionnaires addressing SOC and LOC. The children and parents/caregivers answered their respective modules of the Brazilian version of the Scale of Oral Health Outcomes for 5-year-old children (SOHO-5). Data were also collected on sociodemographic characteristics, visits to the dentist, and the occurrence of toothache. Clinical examinations were performed by 2 trained examiners. A directed acyclic graph was used to select covariates for statistical adjustment, and logistic regression for complex samples was used to test associations between the dependent and independent variables (α = 5%). For parents/caregivers, the variables associated with a negative impact on OHRQoL were the occurrence of toothache (odds ratio, OR: 10.53; 95% confidence interval, CI: 6.34–17.51; p < 0.001) and a low SOC (OR: 2.17; 95% CI: 1.37–3.43; p = 0.001). According to the children’s perceptions, the following variables were associated with a negative impact on OHRQoL: toothache (OR: 3.58; 95% CI: 2.30–5.55; p < 0.001), caries activity (OR: 1.97; 95% CI: 1.07–3.62; p = 0.028), and traumatic dental injury (OR: 1.71; 95% CI: 1.15–2.53; p = 0.007). Among parents/caregivers, a low SOC led to poorer OHRQoL. For the children, however, neither psychological aspect affected OHRQoL. In the perception of both the parents/caregivers and children, toothache was the oral condition that exerted a negative impact on OHRQoL.


2012 ◽  
Vol 83 (1) ◽  
pp. 83-89 ◽  
Author(s):  
Fernanda Sardenberg ◽  
Milene T. Martins ◽  
Cristiane B. Bendo ◽  
Isabela A. Pordeus ◽  
Saul M. Paiva ◽  
...  

Abstract Objective: To test the hypothesis that malocclusion and its impact on quality of life has no effect on 8- to 10-year-old Brazilian schoolchildren as measured by an oral health-related quality of life (OHRQoL) instrument. Materials and Methods: A cross-sectional study was carried out with a population-based sample of 1204 8- to 10-year-old children attending elementary schools in Belo Horizonte, Brazil. Dental examinations were carried out by two calibrated examiners. OHRQoL was assessed using the Brazilian version of the Child Perceptions Questionnaire. The Dental Aesthetic Index was used for the clinical assessment of malocclusion. Dental caries and socioeconomic factors were used as controlling variables. Bivariate analysis involved the chi-square test and the Fisher exact test. A Poisson regression model was employed for the multivariate analysis (P &lt; .05). Results: Anterior segment spacing and anterior mandibular overjet were significantly associated with impact on OHRQoL (P &lt; .05). Schoolchildren with malocclusion were 1.30-fold (95% CI: 1.15–1.46; P &lt; 0.001) more likely to experience a negative impact on OHRQoL than those without malocclusion. Children belonging to families with an income less than or equal to two times the minimum wage were 1.59-fold (95% CI: 1.35–1.88; P &lt; 0.001) more likely to experience a negative impact on OHRQoL than those belonging to families with the highest income. Conclusions: Schoolchildren with malocclusion from lower-income families experience a greater negative impact on OHRQoL.


2016 ◽  
Vol 2 (2) ◽  
pp. 31-35
Author(s):  
Samantha S Komal ◽  
V Srividya

ABSTRACT Introduction Diabetes mellitus is independently associated with lower levels of health-related quality of life (HRQoL). Quality of life (QoL) is an important aspect in diabetes because poor QoL leads to diminished self-care, which in turn leads to worsened glycemic control, increased risks for complications, and exacerbation of diabetes overwhelming in both the short run and the long run. Objective To assess the HRQoL among diabetics aged 18 years and above visiting the Medicine Outpatient Department at RajaRajeswari Medical College and Hospital, Bengaluru. Materials and methods We conducted a hospital-based study using a generic instrument, Audit of Diabetes Dependent Quality of Life 18 (ADDQoL 18) to measure the QoL of diabetic subjects aged ≥18 years. One hundred and forty diabetics, including 68 males and 72 females, were selected from the Medicine Outpatient Department at RajaRajeswari Medical College and Hospital. Data was analyzed using Statistical Package for the Social Sciences for Windows, version 22. Results The mean age of the participants was 55.7 ±12.5 years. Majority of them (75.7%) were Hindu by religion and most of the study participants (60%) had received formal education. Majority (48.6%) belonged to grade 3 socioeconomic status. Diabetic patients who were employed constituted 52.9%. On the type of diabetes, 91.4% of the participants had type 2 diabetes, while 8.6% had type 1 diabetes. The mean duration of diabetes since diagnosis was 8.2 ±6.5 years. With regard to presence or absence of complications, 38.6% of the participants suffered from complications of diabetes, while 61.4% did not. With regard to treatment, 59.3% of them were consuming only oral hypoglycemic, whereas 40.7% were on insulin. It was observed that diabetes had a negative impact on the present QoL with a mean negative impact of –0.45 and a mean negative average weighted impact of –5.16 on the individual life domains. The negative impact of diabetes on the QoL was greater among those receiving insulin ±oral hypoglycemic agents and among those who had complications. The domains “freedom to eat,” “freedom to drink,” “enjoyment of food,” and “working life” had the greatest negative impact in all patient subgroups. It was observed that male diabetics had a poorer QoL as compared with female diabetics, but this was found to be not statistically significant. Conclusion Diabetes had an adverse effect on the QoL of these study subjects. How to cite this article Komal SS, Srividya V. Health-related Quality of Life among Diabetics visiting RajaRajeswari Medical College and Hospital, Bengaluru. J Med Sci 2016;2(2):31-35.


Jurnal NERS ◽  
2020 ◽  
Vol 14 (3) ◽  
pp. 209
Author(s):  
Andrik Hermanto ◽  
Gabriel Wanda Sinawang ◽  
Mohamad Roni Alfaqih ◽  
Rohmatul Faizah

Introduction: Cancer diagnosis can have a profound negative impact on the health-related quality of life (HRQoL) of cancer patients. Cancer patients also suffer from psychological pressures including sadness, depression, hopelessness, anxiety and worry. The literature review was employed to determine the effects of depression on health-related quality of life (HRQoL) in cancer patients.Methods: A systematic review was conducted by searching the Science Direct, Scopus and Google Scholar databases. The integrative review of the 10 articles was focused on the 10 years period from 2008 to 2018. The language used was English and the search was conducted using predefined keywords.Results: All of the journals discussed the impact of depression treatment on health-related quality of life in cancer patients. Based on all of the journals, depression can be reduced by health education, physical activity and medicine therapyConclusion: Despite the treatment for depression, the patient’s HRQoL did not improve during the measurement timeframe. Quality of life is a priority health outcome in cancer treatment but the clinical approaches to ameliorate depression in cancer patients appear to be suboptimal.


2017 ◽  
Vol 65 (4) ◽  
pp. 326-334
Author(s):  
Gustavo TELLO ◽  
Luciana Butini OLIVEIRA ◽  
Christiana MURAKAMI ◽  
Gabriela Cunha BONINI ◽  
Jenny ABANTO ◽  
...  

ABSTRACT Objective: The aim of this study was to investigate the impact of erosive tooth wear on the Oral Health-Related Quality of life (OHRQoL) of preschool children. Methods: Dental examinations were conducted on 815 children aged 3-4 years during the Children’s Vaccination National Day when their parents were also invited to answer the Brazilian Early Childhood Oral Health Impact Scale (B-ECOHIS). ETW prevalence and severity were measured using a modified version of the O’Brien index (1994). Data collected included socioeconomic factors and child's variables. OHRQoL was measured through B-ECOHIS domains and total score. Poisson regression was used to associate ETW to the outcome and this association was adjusted for dental caries and dental trauma. Results: The proportion of children who had at least 1 ETW tooth was 51.2%. Most erosive lesions were confined to enamel (42.7%). The multivariate adjusted model showed that child's age (children aged 4year-old) was associated to a negative impact on the symptom domain (RR=1.70; p=0.010), functional limitation domain (RR=1.85; p=0.005) and total B-ECOHIS score (RR= 1.63; p=0.006). Families with 2 or more children in the house have a negative impact on the self-image/social interaction domain (RR=5.41; p=0.043). ETW was not associated to total B-ECOHIS scores (RR= 0.79; p=0.163) and individual domains. Conclusion: Erosive tooth wear does not affect the OHRQoL in this sample of preschool children.


2019 ◽  
Vol 34 (5) ◽  
pp. 838-848 ◽  
Author(s):  
Sayem Borhan ◽  
Alexandra Papaioannou ◽  
Olga Gajic‐Veljanoski ◽  
Courtney Kennedy ◽  
George Ioannidis ◽  
...  

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