scholarly journals Inhibitory Effects of Human Primary Intervertebral Disc Cells on Human Primary Osteoblasts in a Co-Culture System

2018 ◽  
Vol 19 (4) ◽  
pp. 1195 ◽  
Author(s):  
Rahel D. May ◽  
Daniela A. Frauchiger ◽  
Christoph E. Albers ◽  
Lorin M. Benneker ◽  
Sandro Kohl ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Culture System ◽  
Inhibitory Effects ◽  
Disc Cells ◽  
Primary Osteoblasts ◽  
Human Primary Osteoblasts

Microcarrier bioreactor culture system promotes propagation of human intervertebral disc cells

2010 ◽  
Vol 179 (4) ◽  
pp. 529-534 ◽  
Author(s):  
L. Zhang ◽  
B. Ning ◽  
T. Jia ◽  
W. Gong ◽  
M. Cong ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Culture System ◽  
Bioreactor Culture ◽  
Disc Cells

Effect of TGF-β3 on the Gene Expression of Intervertebral Disc Cells in 3D Pellet Cultures

2010 ◽  
Author(s):  
C. Houseman ◽  
M. Scro ◽  
S. Belverud ◽  
D. Chen ◽  
P. Razzano ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Tissue Regeneration ◽  
Annulus Fibrosus ◽  
Culture System ◽  
Tissue Repair ◽  
Tissue Type ◽  
Disc Cells ◽  
Ivd Degeneration

Intervertebral disc (IVD) degeneration typically involves changes in the multiple constitutive tissues of the IVD. Many tissue repair efforts have focused on the use of differentiated disc cells or stem cells for the regeneration of an IVD in vitro. Consequently, successful long term culture of human disc cells is pivotal for tissue regeneration of the IVD. The aim of this study is to establish a long-term in vitro culture system for the growth of disc cells that maintain their phenotype based on the anatomical origin (annulus fibrosus (AF), nucleus pulposus (NP), or the vertebral end-plates (EP)). This maintenance of phenotype is crucial for examination of treatment efficacy, which is typically designed to induce regeneration of a single tissue type (i.e. injection of growth factors into the NP or anti-inflammatory treatment of the EPs).

New Use of a Three-Dimensional Pellet Culture System for Human Intervertebral Disc Cells

Spine ◽  
2001 ◽  
Vol 26 (21) ◽  
pp. 2316-2322 ◽  
Author(s):  
Joon Yung Lee ◽  
Ronald Hall ◽  
Dalip Pelinkovic ◽  
Ezequiel Cassinelli ◽  
Arvydas Usas ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Culture System ◽  
Three Dimensional ◽  
Pellet Culture ◽  
Disc Cells

DNA Demethylation Regulates Anabolic and Catabolic Gene Expression in Intervertebral Disc Cells

2014 ◽  
Vol 4 (1_suppl) ◽  
pp. s-0034-1376587-s-0034-1376587
Author(s):  
N. Chutkan ◽  
R. Sangani ◽  
H. Zhou ◽  
S. Fulzele
Keyword(s):  
Gene Expression ◽  
Intervertebral Disc ◽  
Dna Demethylation ◽  
Catabolic Gene ◽  
Disc Cells

scholarly journals Effects of Glucose Deprivation on ATP and Proteoglycan Production of Intervertebral Disc Cells under Hypoxia

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Xue Yin ◽  
Aarif Motorwala ◽  
Oraya Vesvoranan ◽  
Howard B. Levene ◽  
Weiyong Gu ◽  
...  
Keyword(s):  
Intervertebral Disc ◽  
Glucose Deprivation ◽  
Disc Cells

scholarly journals An organ culture system to model early degenerative changes of the intervertebral disc II: profiling global gene expression changes

2013 ◽  
Vol 15 (5) ◽  
pp. R121 ◽  
Author(s):  
Dessislava Z Markova ◽  
Christopher K Kepler ◽  
Sankar Addya ◽  
Hallie B Murray ◽  
Alexander R Vaccaro ◽  
...  
Keyword(s):  
Gene Expression ◽  
Intervertebral Disc ◽  
Organ Culture ◽  
Culture System ◽  
Global Gene Expression ◽  
Degenerative Changes ◽  
Organ Culture System

Cell shape and gene expression in human intervertebral disc cells: in vitro tissue engineering studies

2003 ◽  
Vol 78 (2) ◽  
pp. 109-117 ◽  
Author(s):  
He Gruber ◽  
Ja Ingram ◽  
K Leslie ◽  
Hj Norton ◽  
En Hanley Jr
Keyword(s):  
Gene Expression ◽  
Tissue Engineering ◽  
Intervertebral Disc ◽  
Cell Shape ◽  
Engineering Studies ◽  
Disc Cells

Establishment of a Novel Intervertebral Disc/Endplate Culture Model: Analysis of an Ex Vivo In Vitro Whole-Organ Rabbit Culture System

Spine ◽  
2006 ◽  
Vol 31 (25) ◽  
pp. 2918-2925 ◽  
Author(s):  
Daniel Haschtmann ◽  
Jivko V. Stoyanov ◽  
Ladina Ettinger ◽  
Lutz -P. Nolte ◽  
Stephen J. Ferguson
Keyword(s):  
Intervertebral Disc ◽  
Culture System ◽  
Ex Vivo ◽  
Model Analysis ◽  
Culture Model
Sign in / Sign up

Export Citation Format

Share Document