scholarly journals Pentraxin-3 Modulates Osteogenic/Odontogenic Differentiation and Migration of Human Dental Pulp Stem Cells

2019 ◽  
Vol 20 (22) ◽  
pp. 5778
Author(s):  
Yeon Kim ◽  
Joo-Yeon Park ◽  
Hyun-Joo Park ◽  
Mi-Kyoung Kim ◽  
Yong-Il Kim ◽  
...  

Pentraxin-3 (PTX3) is recognized as a modulator of inflammation and a mediator of tissue repair. In this study, we characterized the role of PTX3 on some biological functions of human dental pulp stem cells (HDPSCs). The expression level of PTX3 significantly increased during osteogenic/odontogenic differentiation of HDPSCs, whereas the knockdown of PTX3 decreased this differentiation. Silencing of PTX3 in HDPSCs inhibited their migration and C-X-C chemokine receptor type 4 (CXCR4) expression. Our present study indicates that PTX3 is involved in osteogenic/odontogenic differentiation and migration of HDPSCs, and may contribute to the therapeutic potential of HDPSCs for regeneration and repair.

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Wenzhen Lin ◽  
Li Gao ◽  
Wenxin Jiang ◽  
Chenguang Niu ◽  
Keyong Yuan ◽  
...  

2013 ◽  
Vol 35 (6) ◽  
pp. 543-549 ◽  
Author(s):  
Joo-Hyun Kim ◽  
Eun-Hyang Lee ◽  
Hye-jeong Park ◽  
Eui-Kyun Park ◽  
Tae-Geon Kwon ◽  
...  

2015 ◽  
Vol 94 (11) ◽  
pp. 1560-1567 ◽  
Author(s):  
S. Sohn ◽  
Y. Park ◽  
S. Srikanth ◽  
A. Arai ◽  
M. Song ◽  
...  

2013 ◽  
Vol 36 (5) ◽  
pp. 476-476
Author(s):  
Joo-Hyun Kim ◽  
Eun-Hyang Lee ◽  
Hye-jeong Park ◽  
Eui-Kyun Park ◽  
Tae-Geon Kwon ◽  
...  

2014 ◽  
Vol 40 (2) ◽  
pp. 235-240 ◽  
Author(s):  
Li Cui ◽  
Shuaimei Xu ◽  
Dandan Ma ◽  
Jie Gao ◽  
Ying Liu ◽  
...  

Redox Biology ◽  
2017 ◽  
Vol 12 ◽  
pp. 690-698 ◽  
Author(s):  
Cristina Mas-Bargues ◽  
José Viña-Almunia ◽  
Marta Inglés ◽  
Jorge Sanz-Ros ◽  
Juan Gambini ◽  
...  

Biomaterials ◽  
2011 ◽  
Vol 32 (31) ◽  
pp. 7822-7830 ◽  
Author(s):  
Jing Wang ◽  
Haiyun Ma ◽  
Xiaobing Jin ◽  
Jiang Hu ◽  
Xiaohua Liu ◽  
...  

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