scholarly journals An Unusual Presentation of Crohn’s Disease Diagnosed Following Accidental Ingestion of Fruit Pits: Report of Two Cases and Review of the Literature

Life ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 1415
Author(s):  
Emanuele Sinagra ◽  
Dario Raimondo ◽  
Salvatore Marco Iacopinelli ◽  
Francesca Rossi ◽  
Giuseppe Conoscenti ◽  
...  

The clinical course of Crohn’s disease (CD) is often complicated by intestinal strictures, which can be fibrotic, inflammatory, or mixed, therefore leading to stenosis and eventually symptomatic obstruction. We report two cases of subclinical CD diagnosed after fruit pit ingestion, causing bowel obstruction; additionally, we conducted a narrative review of the scientific literature on cases of intestinal obstruction secondary to impacted bezoars due to fruit pits. Symptoms of gastrointestinal bezoars in CD patients are not diagnostic; and the diagnosis should be based on a combined assessment of history, clinical presentation, imaging examination and endoscopy findings. This report corroborates the concept that CD patients are at a greater risk of bowel obstruction with bezoars generally and shows that accidental ingestion of fruit pits may lead to an unusual presentation of the disease. Therapeutic options in this group of patients differ from the usual approaches implemented in other patients with strictures secondary to CD.

2018 ◽  
Vol 31 (02) ◽  
pp. 080-088 ◽  
Author(s):  
Daniel von Allmen

AbstractThe incidence of Crohn's disease in the pediatric population is increasing. While pediatric patients with Crohn's disease exhibit many of the characteristics of older patients, there are important differences in the clinical presentation and course of disease that can impact the clinical decisions made during treatment. The majority of children are diagnosed in the early teen years, but subgroups of very early onset and infantile Crohn's present much earlier and have a unique clinical course. Treatment paradigms follow the traditional laddered approach, but growth and development represent special considerations that must be given to pediatric-specific complications of the treatment and disease. Surgical intervention is an important component of Crohn's management and is often employed to allow improved nutritional intake or decrease reliance on medical treatments that compromise growth.


2014 ◽  
Vol 2014 (may19 1) ◽  
pp. bcr2013203318-bcr2013203318 ◽  
Author(s):  
F. Mohammad ◽  
A. Vivekanandarajah ◽  
H. Haddad ◽  
C. M. Shutty ◽  
M. T. Hurford ◽  
...  

2021 ◽  
Vol 44 (4) ◽  
pp. 302-303
Author(s):  
Andrea de los Mozos Ruano ◽  
Diego Casas Deza ◽  
Roberto Calvo Galindo ◽  
María Patricia Solana Hidalgo ◽  
Nerea Aguirre Portu ◽  
...  

1995 ◽  
Vol 108 (4) ◽  
pp. A882 ◽  
Author(s):  
A. Musso ◽  
R. Sostegni ◽  
M. Astegiano ◽  
G. Rocca ◽  
M.T. Fiorentini ◽  
...  

2003 ◽  
Vol 124 (4) ◽  
pp. A376
Author(s):  
Vito Annese ◽  
Arnaldo Andreoli ◽  
Bollani Serafina ◽  
Fabiana Castiglione ◽  
Mario Cottone ◽  
...  

2021 ◽  
Vol 14 (6) ◽  
pp. e242703
Author(s):  
Kate Edwards ◽  
Karen Yearsley

A previously well 37-year-old woman attended the emergency assessment unit with symptoms of lethargy, breathlessness and peripheral oedema, whereby initial basic investigations revealed an iron deficiency anaemia and serum hypoalbuminaemia. The patient subsequently had multiple admissions to secondary care over a 2-year period due to worsening peripheral and central oedema. Investigations ruled out non-gastrointestinal causes of serum hypoalbuminaemia, such as renal, cardiac and hepatic failures. Gastrointestinal investigations later revealed raised faecal alpha-1 antitrypsin and small bowel ulceration on capsule endoscopy, with a histological diagnosis of Crohn’s disease made after a small bowel wedge resection. This case describes the unusual presentation of Crohn’s disease displaying symptoms primarily of protein-losing enteropathy, an uncommon and under-recognised consequence of inflammatory bowel disease. A review of current literature and the underlying pathophysiology for this rare condition are discussed, particularly in relation to Crohn’s disease.


PLoS ONE ◽  
2014 ◽  
Vol 9 (11) ◽  
pp. e108503 ◽  
Author(s):  
Fabian Schnitzler ◽  
Matthias Friedrich ◽  
Christiane Wolf ◽  
Marianne Angelberger ◽  
Julia Diegelmann ◽  
...  

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