scholarly journals 3-(3,5-Difluorophenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde

Molbank ◽  
10.3390/m1011 ◽  
2018 ◽  
Vol 2018 (3) ◽  
pp. M1011 ◽  
Author(s):  
Naveen Kumar ◽  
Swamy Sreenivasa ◽  
Vasantha Kumar ◽  
Nadigar Mohan
Keyword(s):  
Spectral Analysis ◽  
1H Nmr ◽  
13C Nmr ◽  
High Purity ◽  
Title Compound ◽  
Good Yield ◽  
Phosphorus Oxychloride ◽  
Structure Characterization ◽  
Dimethyl Formamide

Vilsmeier–Haack reaction of (E)-1-[1-(3,5-difluorophenyl)ethylidene]-2-phenylhydrazine (1) using dimethyl formamide in excess of phosphorus oxychloride by conventional method, resulted in the synthesis of the title compound 3-(3,5-difluorophenyl)-1-phenyl-1H-pyrazole-4- carbaldehyde (2) in good yield and high purity. Structure characterization of the title compound was done by IR, 1H-NMR, 13C-NMR and HRMS spectral analysis.

scholarly journals 3-(3,5-Difluorophenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde

2018 ◽  
Author(s):  
Naveen Kumar ◽  
Swamy Sreenivasa ◽  
Vasantha Kumar ◽  
Nadigar Revansiddappa Mohan
Keyword(s):  
Spectral Analysis ◽  
13C Nmr ◽  
Title Compound ◽  
Structure Characterization ◽  
Dimethyl Formamide ◽  
The Novel ◽  
Mass Spectral Analysis ◽  
Mass Spectral ◽  
Phosphorous Oxychloride

Vilsmeier–Haack reaction of (E)-1-(1-(3,5-difluorophenyl)ethylidene)-2-phenylhydrazine (1) using dimethyl formamide in excess of phosphorous oxychloride by conventional method, resulted in the synthesis of title compound 3-(3,5-difluorophenyl)-1-phenyl-1H-pyrazole-4- carbaldehyde (2) in good yield and high purity. Structure characterization of the novel title compound was done by IR, 1H NMR, 13C NMR and mass spectral analysis.

scholarly journals Ureido Derivatives of Neoabietic Acid

Molbank ◽  
10.3390/m1033 ◽  
2018 ◽  
Vol 2018 (4) ◽  
pp. M1033
Author(s):  
Xinyu Gao ◽  
Niping Feng ◽  
Yuhan Zi ◽  
Jianguo Cao ◽  
Guozheng Huang
Keyword(s):  
Spectral Analysis ◽  
1H Nmr ◽  
13C Nmr ◽  
Structure Characterization ◽  
Curtius Rearrangement ◽  
Neoabietic Acid ◽  
Rearrangement Reaction ◽  
Derivatives Of

A series of ureido derivatives of neoabietic acid were synthesized by application of Curtius rearrangement reaction to neoabietic acid and amines. Structure characterization of these compounds was done by 1H-NMR, 13C-NMR and HRMS spectral analysis.

scholarly journals 1-Methyl-3-{4-[(4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl)benzyl]}-2-phenylindole

Molbank ◽  
10.3390/m1023 ◽  
2018 ◽  
Vol 2018 (4) ◽  
pp. M1023 ◽  
Author(s):  
Jean Guillon ◽  
Solène Savrimoutou ◽  
Sandra Rubio ◽  
Vanessa Desplat
Keyword(s):  
Spectral Analysis ◽  
Cell Lines ◽  
13C Nmr ◽  
Title Compound ◽  
Indole Derivative ◽  
Leukemia Cell ◽  
Structure Characterization ◽  
Cytotoxic Potential ◽  
Leukemia Cell Lines

The 1-methyl-3-{4-[(4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidin-1-yl)benzyl]}-2-phenylindole compound has been successfully synthesized via a multistep pathway starting from 2-phenylindole. Structure characterization of this new indole derivative was done by FTIR, 1H-NMR, 13C-NMR, and HRMS spectral analysis. The title compound showed high cytotoxic potential against five leukemia cell lines (K562, HL60, U937, U266, and Jurkat cell lines).

scholarly journals Synthesis and complete NMR spectral assignments of new benzylamino coumarin derivative

2020 ◽  
Vol 10 (2) ◽  
pp. 12-16
Author(s):  
Vidoslav Dekić ◽  
Niko Radulović ◽  
Milenko Ristić ◽  
Biljana Dekić ◽  
Novica Ristić
Keyword(s):  
Spectral Analysis ◽  
Ethyl Acetate ◽  
1H Nmr ◽  
Resonance Assignment ◽  
13C Nmr ◽  
Spatial Orientation ◽  
Good Yield ◽  
Coumarin Derivative ◽  
Two Dimensional ◽  
Nmr Techniques

This research involves the reaction of 4-chloro-3-nitrocoumarin and (4-methoxyphenyl)methanamine, whereby a novel coumarin derivative 4-[(4-methoxybenzyl) amino]-3-nitro-2H-chromen-2-one was obtained in good yield. The reaction was carried out in ethyl acetate, in the presence of triethylamine. Also, a detailed spectral analysis of a new coumarin derivative is presented. Resonance assignment was achieved using one( 1H NMR and 13C NMR) and two-dimensional NMR techniques (1H1H-COSY, NOESY, HSQC, and HMBC). The NOESY correlations of protons from arylamino substituent and coumarin core indicate their spatial orientation.

scholarly journals SYNTHESIS AND COMPLETE NMR SPECTRAL ASSIGNMENTS OF NEW BENZYLAMINO COUMARIN DERIVATIVE

2020 ◽  
Vol 10 (2) ◽  
Author(s):  
Vidoslav Dekić ◽  
Niko Radulović ◽  
Milenko Ristić ◽  
Biljana Dekić ◽  
Novica Ristić
Keyword(s):  
Spectral Analysis ◽  
Ethyl Acetate ◽  
1H Nmr ◽  
Resonance Assignment ◽  
13C Nmr ◽  
Spatial Orientation ◽  
Good Yield ◽  
Coumarin Derivative ◽  
Two Dimensional ◽  
Nmr Techniques

This research involves the reaction of 4-chloro-3-nitrocoumarin and (4-methoxyphenyl)methanamine, whereby a novel coumarin derivative 4-[(4-methoxybenzyl) amino]-3-nitro-2H-chromen-2-one was obtained in good yield. The reaction was carried out in ethyl acetate, in the presence of triethylamine. Also, a detailed spectral analysis of a new coumarin derivative is presented. Resonance assignment was achieved using one- (1H NMR and 13C NMR) and two-dimensional NMR techniques (1H-1H-COSY, NOESY, HSQC, and HMBC). The NOESY correlations of protons from arylamino substituent and coumarin core indicate their spatial orientation.

Synthesis and Spectral Characterization of New S-Alkylated 1,2,4-Triazoles as Potential Biological Agents

2017 ◽  
Vol 68 (10) ◽  
pp. 2436-2439
Author(s):  
Stefania Felicia Barbuceanu ◽  
Laura Ileana Socea ◽  
Constantin Draghici ◽  
Elena Mihaela Pahontu ◽  
Theodora Venera Apostol ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Spectral Data ◽  
1H Nmr ◽  
Elemental Analysis ◽  
13C Nmr ◽  
Ethyl Bromide ◽  
Spectral Characterization ◽  
Basic Medium ◽  
Phenacyl Bromide

In the work we presented the behavior of 5-(4-(4-X-phenylsulfonyl)phenyl)-4-(n-propyl)-2H-1,2,4-triazole-3(4H)-thiones (X= Cl or Br) with some alkylation agents. Thus, new S-alkylated 1,2,4-triazole derivatives were synthesized by reaction of the corresponding 1,2,4-triazole-3-thione derivatives with different �-halogenated compounds (ethyl bromide, ethyl chloroacetate or phenacyl bromide), in basic medium. The structures of synthesized compounds were elucidated by spectral data (1H-NMR, 13C-NMR, mass spectrometry) and elemental analysis.

Combined High-Resolution Solid-State 1H/13C NMR Spectroscopy and 1H NMR Relaxometry for the Characterization of Kerogen Thermal Maturation

2020 ◽  
Author(s):  
Francesco Panattoni ◽  
Jonathan Mitchell ◽  
Edmund J. Fordham ◽  
Ravinath Kausik ◽  
Clare P. Grey ◽  
...  
Keyword(s):  
Solid State ◽  
Nmr Spectroscopy ◽  
High Resolution ◽  
1H Nmr ◽  
13C Nmr ◽  
13C Nmr Spectroscopy ◽  
Thermal Maturation ◽  
Nmr Relaxometry ◽  
1H Nmr Relaxometry

scholarly journals N-Benzo[c][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide

Molbank ◽  
10.3390/m1075 ◽  
2019 ◽  
Vol 2019 (3) ◽  
pp. M1075 ◽  
Author(s):  
Hamad H. Al Mamari ◽  
Nasser Al Awaimri ◽  
Yousuf Al Lawati
Keyword(s):  
1H Nmr ◽  
Elemental Analysis ◽  
13C Nmr ◽  
Title Compound ◽  
Structural Motif ◽  
Spectroscopic Methods ◽  
Bond Functionalization ◽  
Directing Group ◽  
Metal Catalyzed

The title compound, N-benzo[c][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide (1) was synthesized by reacting 3-trifluoromethylbenzoyl chloride (4) and 4-aminobenzo[c][1,2,5]thiadiazole (5). The compound was characterized by various spectroscopic methods (1H NMR, 13C NMR, IR, GC-MS) and its composition confirmed by elemental analysis. The importance of this compound lies in its possession of an N,N-bidentate directing group. Such a structural motif is potentially suitable for metal-catalyzed C-H bond functionalization reactions.

Synthesis and Characterization of N-butyl-N-methylimidazolium- D-(-)-tartrate Chiral Ionic Liquid

2012 ◽  
Vol 518-523 ◽  
pp. 3989-3992 ◽  
Author(s):  
Yang Zhang ◽  
Xiao Hua Tu ◽  
Cheng Ping Miao ◽  
Jian Yi Wu
Keyword(s):  
Ionic Liquid ◽  
1H Nmr ◽  
Ion Chromatography ◽  
13C Nmr ◽  
Nmr Spectra ◽  
Optical Rotation ◽  
Synthesis And Characterization ◽  
13C Nmr Spectra ◽  
Chiral Ionic Liquid

A novel CIL of N-butyl-N-methyl imidazolium-D-(-)-tartrate has been designed and synthesized by neutralization reaction. Its structure was characterized by 1H-NMR and 13C-NMR spectra, the optical rotation was characterized by polarimeter with the value of-15.0º, and the purity was characterized by ion chromatography with the value of 98.4%.

scholarly journals 6-[1-Acetyl-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazole-3-yl]-2(3H)-benzoxazolone

Molbank ◽  
10.3390/m1021 ◽  
2018 ◽  
Vol 2018 (4) ◽  
pp. M1021
Author(s):  
Yordanka Ivanova ◽  
Antonya Todorova ◽  
Christo Chanev ◽  
Ognyan Petrov
Keyword(s):  
Acetic Acid ◽  
Hydrazine Hydrate ◽  
1H Nmr ◽  
Elemental Analysis ◽  
13C Nmr ◽  
Title Compound ◽  
Target Compound

The title compound, 6-[1-acetyl-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-3-yl]-2(3H)-benzoxazolone, was synthesized by condensation of 6-[3-(4-methoxyphenyl)-2-propenoyl]-2(3H)-benzoxazolone (1) and hydrazine hydrate in acetic acid in 84% yield. The structure of the target compound was confirmed using 1H-NMR, 13C-NMR, IR, MS, and elemental analysis.

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