Marine Natural Products from the Yucatan Peninsula

Mexico is one of the three areas of the world with the greatest terrestrial and cultural biological diversity. The diversity of Mexican medicinal flora has been studied for a long time and several bioactive compounds have been isolated. The investigation of marine resources, and particularly the potential of Mexican marine resources, has not been intensively investigated, even though the Yucatan Peninsula occupies 17.4% of the total of the Mexican coast, with great biological diversity in its coasts and the ocean. There are very few studies on the chemistry of natural products from marine organisms that were collected along the coasts of the Yucatan Peninsula and most of them are limited to the evaluation of the biological activity of their organic extracts. The investigations carried out on marine species from the Yucatan Peninsula resulted in the identification of a wide structural variety of natural products that include polyketides, terpenoids, nitrogen compounds, and biopolymers with cytotoxic, antibacterial, antifouling, and neurotoxic activities. This review describes the literature of bioprospecting and the exploration of the natural product diversity of marine organisms from the coasts of the Yucatan Peninsula up to mid-2019.

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Marine Organisms from the Yucatan Peninsula (Mexico) as a Potential Natural Source of Antibacterial Compounds

Marine Drugs ◽

10.3390/md18070369 ◽

2020 ◽

Vol 18 (7) ◽

pp. 369 ◽

Cited By ~ 1

Author(s):

Dawrin Pech-Puch ◽

Mar Pérez-Povedano ◽

Patricia Gómez ◽

Marta Martínez-Guitián ◽

Cristina Lasarte-Monterrubio ◽

...

Keyword(s):

Marine Organism ◽

Yucatan Peninsula ◽

Antibacterial Activities ◽

Multidrug Resistant ◽

Marine Sponges ◽

Marine Organisms ◽

Human Pathogens ◽

Yucatán Peninsula ◽

Bioassay Guided Fractionation ◽

Agelasine B

A total of 51 sponges (Porifera) and 13 ascidians (Chordata) were collected on the coast of the Yucatan Peninsula (Mexico) and extracted with organic solvents. The resulting extracts were screened for antibacterial activity against four multidrug-resistant (MDR) bacterial pathogens: the Gram-negative Acinetobacter baumannii, Klebsiella pneumoniae, and Pseudomonas aeruginosa and the Gram-positive Staphylococcus aureus. The minimum inhibitory concentrations (MICs) of the organic extracts of each marine organism were determined using a broth microdilution assay. Extracts of eight of the species, in particular the Agelas citrina and Haliclona (Rhizoniera) curacaoensis, displayed activity against some of the pathogens tested. Some of the extracts showed similar MIC values to known antibiotics such as penicillins and aminoglycosides. This study is the first to carry out antimicrobial screening of extracts of marine sponges and ascidians collected from the Yucatan Peninsula. Bioassay-guided fractionation of the active extracts from the sponges Amphimedon compressa and A. citrina displayed, as a preliminary result, that an inseparable mixture of halitoxins and amphitoxins and (-)-agelasine B, respectively, are the major compounds responsible for their corresponding antibacterial activities. This is the first report of the antimicrobial activity of halitoxins and amphitoxins against major multidrug-resistant human pathogens. The promising antibacterial activities detected in this study indicate the coast of Yucatan Peninsula as a potential source of a great variety of marine organisms worthy of further research.

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A new species of cirolanid isopod (Peracarida, Isopoda) collected from Cenote Aerolito, Cozumel Island, northwestern Caribbean

Crustaceana ◽

10.1163/15685403-00003402 ◽

2015 ◽

Vol 88 (2) ◽

pp. 152-163 ◽

Cited By ~ 2

Author(s):

Manuel Ortiz ◽

Sergio Cházaro-Olvera

Keyword(s):

New Species ◽

Yucatan Peninsula ◽

Marine Species ◽

Yucatán Peninsula ◽

Cozumel Island ◽

Appendix Masculina ◽

Mexican Caribbean ◽

A New Species

A new species ofCirolanaLeach, 1818, collected from Cenote Aerolito, Cozumel Island, Mexican Caribbean, is described.Cirolana(Anopsilana)adrianisp. nov. has a body 2.7× as long as wide, widest at pereonites 5-6; cephalon smooth, with small rostral point; pereonites without tubercles or ridges; antenna 2 not surpassing back of segment 2 of pereon; pleonite 4 lacking free ventrolateral margins; pleotelson as long as wide, smooth, with 9 distal robust setae; appendix masculina extremely long, 2× as long as endopod of pleopod 2. The main differences between the new species and the marine speciesCirolana(Anopsilana)jonesi(Kensley, 1987) andC.(A.)sinu(Kensley & Schotte, 1994), as well as the stygobitic speciesC.(A.)yucatanaBotosaneanu & Iliffe, 2000, the most similar known species ofCirolana(Anopsilana) in the region, are described. This is the second isopod of the genusCirolanarecorded from the karstic systems of the Yucatan Peninsula.

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Marine derived tyrosinase inhibitors

Ege Journal of Fisheries and Aquatic Sciences ◽

10.12714/egejfas.37.4.15 ◽

2020 ◽

Vol 37 (4) ◽

pp. 427-436

Author(s):

Amine Dilara Pilevneli ◽

Belma Konuklugil

Keyword(s):

Natural Products ◽

Pharmaceutical Industry ◽

Marine Organisms ◽

Tyrosinase Activity ◽

Marine Resources ◽

New Materials ◽

Skin Whitening ◽

Cosmetic Industry ◽

The World ◽

Tyrosinase Inhibitors

The cosmetics industry has gained strong momentum all over the world in recent years and has become a growing and promising sector. As it is known, as in the pharmaceutical industry, the cosmetic industry has also turned into becoming marine resources by seeking new materials for its continuation to be more productive for the field. To serve this purpose, marine-derived substances are highly claimed to be an interesting as well as a fruitful source for the benefits of the cosmetics industry. In this respect, as known globally, anti-tyrosinase inhibitors used in skin whitening are obtained from a considerable number of marine organisms. In this regard, the main objective of this article is to summarize a highly significant number of natural products derived from marine sources such as algae, fungi, seaweeds and bacteria which are known to have shown anti-tyrosinase activity.

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Antiviral and Antiproliferative Potential of Marine Organisms From the Yucatan Peninsula, Mexico

Frontiers in Marine Science ◽

10.3389/fmars.2020.00607 ◽

2020 ◽

Vol 7 ◽

Author(s):

Dawrin Pech-Puch ◽

Judith Berastegui-Cabrera ◽

Mar Pérez-Povedano ◽

Harold Villegas-Hernández ◽

Sergio Guillén-Hernández ◽

...

Keyword(s):

Yucatan Peninsula ◽

Marine Organisms ◽

Yucatán Peninsula

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When Dinosaurs Became Extinct, What Happened to the Insects?

Microscopy Today ◽

10.1017/s1551929500058429 ◽

2002 ◽

Vol 10 (6) ◽

pp. 3-4

Author(s):

Stephen W. Carmichael

Keyword(s):

Mass Extinction ◽

Fossil Record ◽

Yucatan Peninsula ◽

Indirect Evidence ◽

Marine Species ◽

Yucatán Peninsula

It is widely accepted that approximately 65 million years ago, an extraterrestrial object slammed into the Yucatán Peninsula of Mexico, creating a worldwide climatic shift that wiped out the dinosaurs, and many other terrestrial and marine species. But what happened to the insects? They undoubtedly represented a larger biomass than the dinosaurs, but it's fair to say they haven't captured the public's imagination in the same way. The reason the fate of the insects has not been adequately explored is due to the paucity of the available fossil record of the insect bodies. There are a few records of insects embedded in amber or fossilized, but practically none are available from the time of mass extinction referred to as the Cretaceous-Paleocene boundary. Recently, Conrad Labandeira, Kirk Johnson, and Peter Wiif found an ingenious way to examine indirect evidence and show what happened to the insects during this time.

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Octopus maya parasites off the Yucatán Peninsula, Mexico. II. Salivary gland damage by cestodes

Diseases of Aquatic Organisms ◽

10.3354/dao03252 ◽

2018 ◽

Vol 130 (1) ◽

pp. 45-50 ◽

Cited By ~ 1

Author(s):

S Guillén-Hernández ◽

C González-Salas ◽

D Pech-Puch ◽

H Villegas-Hernández

Keyword(s):

Salivary Gland ◽

Yucatan Peninsula ◽

Yucatán Peninsula ◽

Octopus Maya

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Antitubercular Marine Natural Products

Current Medicinal Chemistry ◽

10.2174/0929867324666170113120221 ◽

2018 ◽

Vol 25 (20) ◽

pp. 2304-2328 ◽

Cited By ~ 4

Author(s):

Lishu Wang ◽

Jungfeng Wang ◽

Juan Liu ◽

Yonghong Liu

Keyword(s):

Natural Products ◽

Marine Natural Products ◽

Antitubercular Activity ◽

Marine Resources ◽

Drug Candidates ◽

New Drug ◽

Chemical Constitution

Due to the importance of nature as a source of new drug candidates, the purpose of this article is to emphasize the marine natural products, which exhibit antitubercular activity, published between January 2000 and May 2016, with 138 quotations to 250 compounds obtained from marine resources. These metabolites are organized by chemical constitution and named as simple alkyl lipids derivatives, aromatics derivatives, peptides, alkaloids, terpenoids, steroids, macrolides, and polycyclic polyketides.

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