The Microstructure, Antibacterial and Antitumor Activities of Chitosan Oligosaccharides and Derivatives

Chitosan obtained from abundant marine resources has been proven to have a variety of biological activities. However, due to its poor water solubility, chitosan application is limited, and the degradation products of chitosan oligosaccharides are better than chitosan regarding performance. Chitosan oligosaccharides have two kinds of active groups, amino and hydroxyl groups, which can form a variety of derivatives, and the properties of these derivatives can be further improved. In this review, the key structures of chitosan oligosaccharides and recent studies on chitosan oligosaccharide derivatives, including their synthesis methods, are described. Finally, the antimicrobial and antitumor applications of chitosan oligosaccharides and their derivatives are discussed.

Subsistence Strategy of Here Sorot Entapa Cave in Kisar Island, Maluku: Dwelling Site in Island with Limited Terrestrial Resources

Penelitian di wilayah Wallacea selalu menghasilkan informasi yang menarik, salah satunya adalah mengenai peran pulau-pulau yang berada di wilayah ini dalam jalur migrasi manusia. Beberapa pulau kecil yang ada di wilayah ini merupakan pulau dengan sumber daya alam yang terbatas. Gua Here Sorot Entapa merupakan salah satu situs yang terletak di Kawasan Wallacea bagian Tenggara, yaitu di Pulau Kisar. Hasil ekskavasi yang dilakukan telah menemukan akumulasi artefak, ekofak dan fitur. Lalu bagaimana adaptasi yang dilakukan oleh manusia pada masa itu terhadap lingkungan dengan sumberdaya alam yang terbatas, merupakan hal yang akan dibahas dalam tulisan ini. Metode yang digunakan dalam tulisan ini adalah analisis hasil ekskavasi yang dilakukan oleh Tim Penelitian gabungan UGM dan ANU serta Balai Arkeologi Maluku. Untuk mengetahui perubahan lingkungan dan pemanfaatannya akan digunakan data botani yang diperoleh secara langsung maupun studi pustaka. Hasil dari penelitian ini menunjukkan bahwa Gua Here Sorot Entapa dihuni sejak sekitar 16.000 BP. Pemanfaatan sumberdaya laut merupakan subsistensi utama di samping pemanfaatan beberapa jenis tumbuhan yang secara kuantitas berbanding lurus dengan pemanfaatan sumberdaya laut. Research in the Wallacea area always produces exciting information, including the role of the islands in this region in human migration routes. Several small islands in this region are islands with limited terrestrial resources. Here Sorot Entapa cave is one of the sites located on Kisar Island, Southeast Wallacea region. The occupation of small islands presents particular challenges for human communities related to limited terrestrial resources and susceptibility to natural disasters. Then how the adaptation made by humans at that time in an environment with limited terrestrial resources is discussed in this study. This study used excavation methods to obtain data accumulation of artifacts, ecofacts, and features. Literature study and botanical data analysis were used to determine environmental changes and resource utilization. The results of this study indicate that the Here Sorot Entapa Cave has been occupied since around 16,000 BP. Marine resources were the primary subsistence along with several types of plants food in the same quantity. The function of the Here Sorot Entapa Cave may also be related to the existence of rock art that spread on Kisar Island. Eventually, Kisar Island was the main purpose of a prehistoric human in carrying out religious and artistic activities, and the Here Sorot Entapa Cave served as a temporary shelter for these activities.

Level of Awareness on Disaster Risk Reduction of the University of Eastern Philippines Employees and Students

The researchers looked at how well academics, students, and non-teaching staff at the University of Eastern Philippines System were aware of disaster risk reduction. Education, agriculture, health, fisheries, and marine resources were all used to measure awareness. The research also revealed a link between awareness and a number of personal characteristics, as well as a substantial variation in awareness amongst student groups. The study used a 30-item Likert type instrument to assess disaster risk reduction awareness and used a descriptive-correlational research approach. Percentages, means, multiple regression analysis, and analysis of variance were used to examine the data. The study's findings revealed that faculty members were well-versed in disaster risk reduction in education, agriculture, and health, as well as disaster risk reduction in fisheries and marine resources, infrastructure, and the environment and natural resources. The students were well-informed on disaster risk reduction in the areas of education, agriculture, and health, as well as disaster risk reduction in the areas of fisheries and marine resources, infrastructure, and the environment and natural resources. The six components of the degree of awareness were known to the non-teaching employees. Exposure to newspapers and television was shown to be substantially associated to the level of disaster risk reduction knowledge among faculty and non-teaching personnel. Students' newspaper exposure and year levels were shown to be substantially connected to their degree of disaster risk reduction knowledge. There is a considerable variation in disaster risk reduction awareness across the three categories of respondents.