scholarly journals Pain Characteristics and Associations with Quality of Life in Patients with Multiple Sclerosis in Lithuania

Medicina ◽  
2020 ◽  
Vol 56 (11) ◽  
pp. 596
Author(s):  
Greta Veličkaitė ◽  
Neringa Jucevičiūtė ◽  
Renata Balnytė ◽  
Ovidijus Laucius ◽  
Antanas Vaitkus

Background and objectives: Even though pain in multiple sclerosis (MS) patients is common and possibly associated with reduced quality of life, its exact prevalence and characteristics remain vaguely understood. We aimed to estimate the true extent of pain and its associations with quality of life in Lithuanian MS patients and to compare this data with that of a control group. Materials and Methods: Data were collected prospectively at the Department of Neurology, Lithuanian University of Health Sciences Kaunas Clinics. A face-to-face structured interview and a questionnaire were used to collect demographic and clinical data of the MS (n = 120) and control (n = 120) groups. The Expanded Disability Status Scale (EDSS) was used to quantify disability in the MS group. Scores ≥4/10 in the Douleur Neuropathique 4 questionnaire were classified as neuropathic pain. Patients were evaluated using the anxiety and depression subsets of the Hospital Anxiety and Depression Scale (HADS-A and HADS-D), the physical and mental component subsets of the Short Form-12 questionnaire (PSC-12 and MSC-12). Results: The MS and control groups did not differ in pain prevalence (76.7% vs. 65.9%, p = 0.064) or intensity. Lhermitte sign, lower limb, and face pain were more common in the MS group, whereas subjects in the control group were more often affected by lower back, neck, and joint pain. Neuropathic pain and pain lasting longer than 2 years were more common among pain-affected MS patients than among controls. MS patients with pain had higher EDSS, HADS-D, and HADS-A and lower PSC-12 scores than those without pain; however, no difference was found regarding the duration of MS or age. Males with MS and pain had higher MSC-12 and HADS-D scores in comparison to the same subset of females. Conclusions: Pain affects approximately three out of four patients with MS in Lithuania and is negatively associated with the mental and physical aspects of quality of life.

2009 ◽  
Vol 37 (4) ◽  
pp. 1108-1114 ◽  
Author(s):  
Y Chai ◽  
Y Shao ◽  
S Lin ◽  
K-Y Xiong ◽  
W-S Chen ◽  
...  

The potential impact of the surgical correction of strabismus on vision-related quality of life (VRQOL) and the symptoms of anxiety and depression in children with strabismus remain unclear. The present study included 60 children with strabismus: 30 with heterophoria and 30 with heterotropia. A healthy age-and gender-matched control group ( n = 60) was also recruited. The psychological instruments that were used were the short-form 25-item National Eye Institute Visual Functioning Questionnaire (NEI-VFQ-25) and the Hospital Anxiety and Depression Scale (HADS). The results demonstrated that eight of the 12 NEI-VFQ-25 subscales were significantly impaired in children with strabismus compared with matched controls. Compared with pre-operative values, significant improvements were noted after surgery in the NEI-VFQ-25 summary score, and the anxiety and depression scores. This study demonstrated that the NEI-VFQ-25 instrument can be used in strabismus children and that surgical interventions can improve VRQOL, anxiety and depression in strabismus patients.


2005 ◽  
Vol 11 (3) ◽  
pp. 322-327 ◽  
Author(s):  
Lorraine V Kalia ◽  
Paul W OConnor

Introduction: This study used reliable and validated instruments to compare pain severity in multiple sclerosis (MS) to that in other chronic painful conditions, and to examine relationships between chronic pain in MS and health-related quality of life (HRQOL). Methods: Ninety-nine MS patients completed a self-administered survey comprised of the Medical Outcomes 36-Item Short-Form Health Survey, the Short-Form McGill Pain Questionnaire, and the Hospital Anxiety and Depression Scale. Results: Pain severity was not different between MS patients with pain and rheumatoid arthritis (P=0.77) or osteoarthritis (P=0.98) patients. Chronic pain in MS was less often neurogenic than non-neurogenic, although severity of neurogenic pain was greater than that of non-neurogenic pain (P=0.048). Chronic pain in MS was found to have no significant relationship to age, disease duration or disease course. Instead, we found that pain was correlated with aspects of HRQOL, particularly mental health (r=0.44, P<0.0001) versus physical functioning (r=0.19, P>0.05). Chronic pain was significantly related to anxiety and depression for females but not for males with MS. Conclusions: Chronic pain in MS is as severe as pain in arthritic conditions and is associated with reduced HRQOL. Thus, pain can be a significant symptom for MS patients and the need for treatment may be underestimated.


2011 ◽  
Vol 26 (S2) ◽  
pp. 1661-1661
Author(s):  
Y. El Kissi ◽  
J. Mannai ◽  
N. Kenani ◽  
R. Nouira ◽  
B. Ben Hadj Ali

IntroductionPsychological profile and quality of life of patients suffering from Dermatitis artefact (DA) have never been assessed in a standardized and comparative way.ObjectiveTo compare anxiety, depression and quality of life in patients with DA and in patients with other chronic skin illnessMaterial and methodsThirty patients meeting DSM-IV criteria of Dermatitis artefact were recruited in dermatology department of Farhat Hached hospital (Sousse, Tunisia). Control group consisted of 30 patients with other chronic dermatitis, randomly selected and matched for age and disease duration. Anxiety and depression were assed using the Hospital Anxiety and Depression Scale (HAD-S). Quality of life was measured by the MOS 36-Item Short-Form Health Survey (SF-36).ResultsCompared with controls, patients with DA had an impaired quality of life (p < 10-3). They had lower scores in physical activity (p = 10-3), limitations due to physical condition (p = 0.024), physical pain (p < 10-3), perception of health (p < 10-3). They also had lower scores in vitality (p = 0.005), social dysfunction (p = 0.003), limitations due to mental condition (p < 10-3) and mental health (p < 10-3). Anxiety and depression scores showed no differences between DA patients and controls.ConclusionCompared to patients with other chronic dermatological conditions, patients suffering from DA had a more impaired quality of life, but they were no more depressed or anxious.


2017 ◽  
Vol 7 (12) ◽  
pp. 52
Author(s):  
Rasha Ali Ahmed Abdelmowla ◽  
Attyiat Hassan Hussein ◽  
Ahmed Abdelhamaid Shahat ◽  
Hanan Ali Ahmed Abdelmowla ◽  
Medhat Ahmed Abdalla

Background and objective: Renal stones are a common and recurrent condition that requires medical or surgical treatment; all have significant impact on quality of life. The objective of this study was to detect factors affecting quality of life, improve quality of life for patients with renal stones treated by percutaneous nephrolithotomy.Methods: Research design: Prospective randomized controlled trail. Patients and methods: Random sample of 160 patients with renal stones planned for treatment by percutaneous nephrolithotomy at Assiut Urology and Nephrology Hospital were randomized into study and control groups. Study group (80 patients who received nursing interventions and patients education) and control group (80 patients who received routine hospital care). Their age ranged from18-65 years from both sexes. Tools: I Patient assessment sheet, II Rand short form 36 items questionnaire and III Teaching booklet.Results: Study group was showed a good improvement on quality of life after providing nursing interventions and patients education.Conclusions and recommendation: Nursing interventions and patients education for study group had a favorable effect on improving quality of life. Patients with percutaneous nephrolithotomy should receive careful care and education to improve their quality of life.


2009 ◽  
Vol 102 (12) ◽  
pp. 1219-1226 ◽  
Author(s):  
Paul Lukas ◽  
René Krummenacher ◽  
Franziska Biasiutti ◽  
Stefan Begré ◽  
Hansjörg Znoj ◽  
...  

SummaryHealth-related quality of life (QoL) has been associated with several social and medical conditions in patients with deep vein thrombosis (DVT) and pulmonary embolism (PE).To the best of our knowledge,there is no study investigating the relationship of QoL with psychological variables in this patient population.We assumed as a hypothesis an association between heightened levels of fatigue and psychological distress, as well as decreased QoL in patients with an objectively diagnosed venous thromboembolic event. Study participants were 205 consecutively enrolled out-patients (47.4 years, 54.6% men) with DVT and/or PE. Approximately 10 days before blood collection for thrombophilia work-up, QoL, fatigue, and psychological distress were assessed using the Short Form Health Survey (SF-12), the Multidimensional Fatigue Symptom Inventory Short Form (MFSI-SF) as well as the Hospitality Anxiety and Depression scale (HADS). After controlling for demographic and medical factors, fatigue (p<0.01) but not psychological distress (p>0.05) was negatively associated with physical QoL, explaining 11.0% of the variance. Fatigue (p<0.001) and psychological distress (p<0.001) were significant predictors of mental QoL,explaining an additional 36.2% and 3.6% of the variance. Further analyses revealed that all subscales of the HADS (e.g. anxiety and depression) and of the MFSI-SF (e.g. general fatigue, physical fatigue, emotional fatigue, mental fatigue and vigor) were significant predictors of mental QoL. MFSI-SF subscales also predicted physical QoL. The findings suggest that fatigue and psychological distress substantially predict QoL in patients with a previous venous thromboembolic event above and beyond demographic factors.


2017 ◽  
Vol 28 (6) ◽  
pp. 726-743 ◽  
Author(s):  
Mei-Hua Kao ◽  
Pi-Feng Hsu ◽  
Sheng-Fang Tien ◽  
Chie-Pein Chen

This study was to examine the effects of support interventions on anxiety, depression, and quality of life in women hospitalized with preterm labor. A randomized, single-blind experimental design was used. Participants were recruited from maternity wards of one medical center in Taiwan. The control group ( n = 103) received routine nursing care, and intervention group ( n = 140) received interventional support during hospitalization. The Beck Anxiety Inventory, Edinburgh Postnatal Depression Scale, and Quality of Life Enjoyment and Satisfaction Questionnaire were used at admission and 2 weeks of hospitalization. For the control group, anxiety and depression scores increased significantly and quality of life decreased 2 weeks after hospitalization. Participants who received 2 weeks of support intervention had significantly lower anxiety and depression scores than controls. Thus, clinical nurses can offer support interventions to improve anxiety and depression for women with preterm labor during hospitalization.


Neurosurgery ◽  
2009 ◽  
Vol 65 (3) ◽  
pp. 565-573 ◽  
Author(s):  
Joseph T. King ◽  
Joel Tsevat ◽  
Mark S. Roberts

Abstract OBJECTIVE Cerebral aneurysms can adversely affect quality of life (QOL) via mass effect, subarachnoid hemorrhage, anxiety, or treatment sequelae. The EuroQol EQ-5D is a popular generic 5-item multiple-choice survey questionnaire that measures preference-based QOL on a 0 to 1 scale. We assessed the validity and reliability of the EQ-5D in patients with cerebral aneurysms. METHODS We collected data from 178 neurosurgery clinic patients with cerebral aneurysms. Patients were assigned Glasgow Outcome Scale, Rankin scale, Barthel index, and Physical Performance Test scores, and completed the Short-Form 12, Hospital Anxiety and Depression scale, and the EQ-5D. We assessed the construct validity of the EQ-5D by comparing the EQ-5D and the other scales using rank-order methods and multivariate linear regression. Reliability was assessed with Cronbach's α. RESULTS Patients had a mean age of 54.7 years (standard deviation, 12.6 years), 131 (74%) were women, and 98 (55%) had survived a subarachnoid hemorrhage. The mean EQ-5D score was 0.80 (standard deviation, 0.19). Construct validity of the EQ-5D was confirmed by statistically significant associations between EQ-5D and Glasgow Outcome Scale, Rankin scale, Barthel index, Physical Performance Test, Short-Form 12 Physical Component Summary, and Hospital Anxiety and Depression scores (for all, P ≤ 0.05). Multivariate regression showed that the EQ-5D scores were independently associated with the Barthel index, Short-Form 12 Physical Component Summary, and Hospital Anxiety and Depression scale anxiety and depression subscales (pseudo R2 = 0.40). Reliability was demonstrated by Cronbach's α of 0.70. CONCLUSION The EQ-5D is a valid and reliable instrument for measuring QOL in patients with cerebral aneurysms. The EQ-5D provides a single QOL value incorporating functional status, physical functioning, and mental health.


2020 ◽  
Vol 6 (2) ◽  
pp. 100-107
Author(s):  
Seyyed Hadi Rafiee ◽  
◽  
Somayyeh Taklavi ◽  
Abbas Abolghasemi ◽  
Hamidreza Ghalyanchi Langroodi ◽  
...  

Background: Multiple Sclerosis (MS) is one of the disorders of the central nervous system which creates many challenges for the psychological adjustment of patients all over the world. Objectives:This research was performed to demonstrate the effect of positive group-psychotherapy on reducing the psychological symptoms (depression, anxiety, and stress) and improving the quality of life in women with MS. Materials & Methods: The method of this research is quasi-experimental with pre-test, post-test, and control group. A total of 30 women were selected through a convenient sampling method from the patients of the MS-Society of Guilan Province, Iran. Then, they and randomly divided into 2 equal groups (experimental and control). The study data were collected through Depression Anxiety Stress Scale (DASS) and Multiple Sclerosis Impact Scale‐29 (MSIS) questionnaires. The intervention process was performed for the experimental group as 8 training sessions of 90 minutes long. The obtained data were analyzed by univariate analysis of covariance and multivariate analysis of covariance in SPSS V. 24. Results: The analysis showed that positive group-psychotherapy significantly modified the depression, anxiety, stress (F=39.13, P<0.001), and quality of life (F=50.44, P<0.001) in the experimental group. Conclusion: Positive group-psychotherapy can be used as an effective and efficient psychotherapy method to reduce and improve the psychological symptoms (depression, anxiety, and stress) of women with multiple sclerosis and improve their quality of life.


2021 ◽  
Vol 18 (4) ◽  
pp. 869-892
Author(s):  
Olga Yu. Shchelkova ◽  
Ekaterina B. Usmanova ◽  
Maria V. Iakovleva ◽  
Vsevolod B. Matveev ◽  
Oybek A. Khalmurzaev ◽  
...  

Research into the psychological aspects of oncological diseases is nowadays relevant and widespread; however, there are very few studies in patients with penile cancer (PC). Therefore, the purpose of this pilot study is to investigate the psychological characteristics and quality of life of patients with PC for further organization of psychological counseling. The study included 17 male patients (mean age 49.0 3.76 years) of the N.N. Blokhin National Medical Research Center of Oncology. The following techniques were used: Hospital Anxiety and Depression Scale (HADS), Big Five Inventory (BFI), Ways of Coping Questionnaire (WCQ), Purpose in Life Test (PLT), Quality of Life of Cancer Patients (EORTC QLQ-C30). The patients overall health status was assessed by D.A. Karnofskys scale; a specific psychological structured interview was also conducted. The emotional state of most patients is characterized by low indexes of anxiety and depression. Most of them are purposeful, organized, emotionally stable, unwilling to form trusting relationships. They have high rates of life meaningfulness, a normative level of internality and a decreased purpose in life indicator. The patients are not prone to active and conscious overcoming stress compared to healthy men. The indexes of quality of life, as well as the rates of its specific parameters (cognitive, physical and emotional activity) in the studied group of patients exceed the same values in patients with different tumor localizations and are not consistent with the objectively estimated condition. Health-related quality of life is largely determined by the characteristics of patients value system, especially in oncological diseases that are related not only to a vital threat, but also to deep personal experiences, including the experience of patients male identity.


Sign in / Sign up

Export Citation Format

Share Document