Association of fatigue and psychological distress with quality of life in patients with a previous venous thromboembolic event

2009 ◽  
Vol 102 (12) ◽  
pp. 1219-1226 ◽  
Author(s):  
Paul Lukas ◽  
René Krummenacher ◽  
Franziska Biasiutti ◽  
Stefan Begré ◽  
Hansjörg Znoj ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Psychological Distress ◽  
Thromboembolic Event ◽  
Short Form ◽  
Depression Scale ◽  
Venous Thromboembolic Event ◽  
Anxiety And Depression ◽  
Blood Collection ◽  
Venous Thromboembolic

SummaryHealth-related quality of life (QoL) has been associated with several social and medical conditions in patients with deep vein thrombosis (DVT) and pulmonary embolism (PE).To the best of our knowledge,there is no study investigating the relationship of QoL with psychological variables in this patient population.We assumed as a hypothesis an association between heightened levels of fatigue and psychological distress, as well as decreased QoL in patients with an objectively diagnosed venous thromboembolic event. Study participants were 205 consecutively enrolled out-patients (47.4 years, 54.6% men) with DVT and/or PE. Approximately 10 days before blood collection for thrombophilia work-up, QoL, fatigue, and psychological distress were assessed using the Short Form Health Survey (SF-12), the Multidimensional Fatigue Symptom Inventory Short Form (MFSI-SF) as well as the Hospitality Anxiety and Depression scale (HADS). After controlling for demographic and medical factors, fatigue (p<0.01) but not psychological distress (p>0.05) was negatively associated with physical QoL, explaining 11.0% of the variance. Fatigue (p<0.001) and psychological distress (p<0.001) were significant predictors of mental QoL,explaining an additional 36.2% and 3.6% of the variance. Further analyses revealed that all subscales of the HADS (e.g. anxiety and depression) and of the MFSI-SF (e.g. general fatigue, physical fatigue, emotional fatigue, mental fatigue and vigor) were significant predictors of mental QoL. MFSI-SF subscales also predicted physical QoL. The findings suggest that fatigue and psychological distress substantially predict QoL in patients with a previous venous thromboembolic event above and beyond demographic factors.

scholarly journals Pain Characteristics and Associations with Quality of Life in Patients with Multiple Sclerosis in Lithuania

Medicina ◽  
2020 ◽  
Vol 56 (11) ◽  
pp. 596
Author(s):  
Greta Veličkaitė ◽  
Neringa Jucevičiūtė ◽  
Renata Balnytė ◽  
Ovidijus Laucius ◽  
Antanas Vaitkus
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Neuropathic Pain ◽  
Short Form ◽  
Depression Scale ◽  
Structured Interview ◽  
Anxiety And Depression ◽  
Control Group ◽  
And Control

Background and objectives: Even though pain in multiple sclerosis (MS) patients is common and possibly associated with reduced quality of life, its exact prevalence and characteristics remain vaguely understood. We aimed to estimate the true extent of pain and its associations with quality of life in Lithuanian MS patients and to compare this data with that of a control group. Materials and Methods: Data were collected prospectively at the Department of Neurology, Lithuanian University of Health Sciences Kaunas Clinics. A face-to-face structured interview and a questionnaire were used to collect demographic and clinical data of the MS (n = 120) and control (n = 120) groups. The Expanded Disability Status Scale (EDSS) was used to quantify disability in the MS group. Scores ≥4/10 in the Douleur Neuropathique 4 questionnaire were classified as neuropathic pain. Patients were evaluated using the anxiety and depression subsets of the Hospital Anxiety and Depression Scale (HADS-A and HADS-D), the physical and mental component subsets of the Short Form-12 questionnaire (PSC-12 and MSC-12). Results: The MS and control groups did not differ in pain prevalence (76.7% vs. 65.9%, p = 0.064) or intensity. Lhermitte sign, lower limb, and face pain were more common in the MS group, whereas subjects in the control group were more often affected by lower back, neck, and joint pain. Neuropathic pain and pain lasting longer than 2 years were more common among pain-affected MS patients than among controls. MS patients with pain had higher EDSS, HADS-D, and HADS-A and lower PSC-12 scores than those without pain; however, no difference was found regarding the duration of MS or age. Males with MS and pain had higher MSC-12 and HADS-D scores in comparison to the same subset of females. Conclusions: Pain affects approximately three out of four patients with MS in Lithuania and is negatively associated with the mental and physical aspects of quality of life.

scholarly journals Vision-Related Quality of Life and Emotional Impact in Children with Strabismus: A Prospective Study

2009 ◽  
Vol 37 (4) ◽  
pp. 1108-1114 ◽  
Author(s):  
Y Chai ◽  
Y Shao ◽  
S Lin ◽  
K-Y Xiong ◽  
W-S Chen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Depression Scale ◽  
Summary Score ◽  
Anxiety And Depression ◽  
Control Group ◽  
Emotional Impact ◽  
Surgical Interventions ◽  
Related Quality

The potential impact of the surgical correction of strabismus on vision-related quality of life (VRQOL) and the symptoms of anxiety and depression in children with strabismus remain unclear. The present study included 60 children with strabismus: 30 with heterophoria and 30 with heterotropia. A healthy age-and gender-matched control group ( n = 60) was also recruited. The psychological instruments that were used were the short-form 25-item National Eye Institute Visual Functioning Questionnaire (NEI-VFQ-25) and the Hospital Anxiety and Depression Scale (HADS). The results demonstrated that eight of the 12 NEI-VFQ-25 subscales were significantly impaired in children with strabismus compared with matched controls. Compared with pre-operative values, significant improvements were noted after surgery in the NEI-VFQ-25 summary score, and the anxiety and depression scores. This study demonstrated that the NEI-VFQ-25 instrument can be used in strabismus children and that surgical interventions can improve VRQOL, anxiety and depression in strabismus patients.

Severity of chronic pain and its relationship to quality of life in multiple sclerosis

2005 ◽  
Vol 11 (3) ◽  
pp. 322-327 ◽  
Author(s):  
Lorraine V Kalia ◽  
Paul W OConnor
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Chronic Pain ◽  
Short Form ◽  
Depression Scale ◽  
Pain Severity ◽  
Anxiety And Depression ◽  
Mcgill Pain Questionnaire ◽  
Neurogenic Pain

Introduction: This study used reliable and validated instruments to compare pain severity in multiple sclerosis (MS) to that in other chronic painful conditions, and to examine relationships between chronic pain in MS and health-related quality of life (HRQOL). Methods: Ninety-nine MS patients completed a self-administered survey comprised of the Medical Outcomes 36-Item Short-Form Health Survey, the Short-Form McGill Pain Questionnaire, and the Hospital Anxiety and Depression Scale. Results: Pain severity was not different between MS patients with pain and rheumatoid arthritis (P=0.77) or osteoarthritis (P=0.98) patients. Chronic pain in MS was less often neurogenic than non-neurogenic, although severity of neurogenic pain was greater than that of non-neurogenic pain (P=0.048). Chronic pain in MS was found to have no significant relationship to age, disease duration or disease course. Instead, we found that pain was correlated with aspects of HRQOL, particularly mental health (r=0.44, P<0.0001) versus physical functioning (r=0.19, P>0.05). Chronic pain was significantly related to anxiety and depression for females but not for males with MS. Conclusions: Chronic pain in MS is as severe as pain in arthritic conditions and is associated with reduced HRQOL. Thus, pain can be a significant symptom for MS patients and the need for treatment may be underestimated.

Measuring Preference-Based Quality of Life Using the Euroqol Eq-5D in Patients with Cerebral Aneurysms

Neurosurgery ◽  
2009 ◽  
Vol 65 (3) ◽  
pp. 565-573 ◽  
Author(s):  
Joseph T. King ◽  
Joel Tsevat ◽  
Mark S. Roberts
Keyword(s):  
Quality Of Life ◽  
Barthel Index ◽  
Performance Test ◽  
Short Form ◽  
Depression Scale ◽  
Cerebral Aneurysms ◽  
Anxiety And Depression ◽  
Physical Performance Test ◽  
Hospital Anxiety

Abstract OBJECTIVE Cerebral aneurysms can adversely affect quality of life (QOL) via mass effect, subarachnoid hemorrhage, anxiety, or treatment sequelae. The EuroQol EQ-5D is a popular generic 5-item multiple-choice survey questionnaire that measures preference-based QOL on a 0 to 1 scale. We assessed the validity and reliability of the EQ-5D in patients with cerebral aneurysms. METHODS We collected data from 178 neurosurgery clinic patients with cerebral aneurysms. Patients were assigned Glasgow Outcome Scale, Rankin scale, Barthel index, and Physical Performance Test scores, and completed the Short-Form 12, Hospital Anxiety and Depression scale, and the EQ-5D. We assessed the construct validity of the EQ-5D by comparing the EQ-5D and the other scales using rank-order methods and multivariate linear regression. Reliability was assessed with Cronbach's α. RESULTS Patients had a mean age of 54.7 years (standard deviation, 12.6 years), 131 (74%) were women, and 98 (55%) had survived a subarachnoid hemorrhage. The mean EQ-5D score was 0.80 (standard deviation, 0.19). Construct validity of the EQ-5D was confirmed by statistically significant associations between EQ-5D and Glasgow Outcome Scale, Rankin scale, Barthel index, Physical Performance Test, Short-Form 12 Physical Component Summary, and Hospital Anxiety and Depression scores (for all, P ≤ 0.05). Multivariate regression showed that the EQ-5D scores were independently associated with the Barthel index, Short-Form 12 Physical Component Summary, and Hospital Anxiety and Depression scale anxiety and depression subscales (pseudo R2 = 0.40). Reliability was demonstrated by Cronbach's α of 0.70. CONCLUSION The EQ-5D is a valid and reliable instrument for measuring QOL in patients with cerebral aneurysms. The EQ-5D provides a single QOL value incorporating functional status, physical functioning, and mental health.

scholarly journals Distress and quality of life do not change over time in patients with operated and conservatively managed intracranial meningioma

2021 ◽  
Author(s):  
Darius Kalasauskas ◽  
Naureen Keric ◽  
Salman Abu Ajaj ◽  
Leoni von Cube ◽  
Florian Ringel ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Psychological Distress ◽  
Symptom Severity ◽  
Short Form ◽  
Depression Scale ◽  
Intracranial Meningioma ◽  
Excellent Outcome ◽  
Number Of Patients

Abstract Purpose The patients’ burden with asymptomatic meningiomas and patients with good clinical outcome after meningioma resection often remains neglected. In this study, we aimed to investigate the longitudinal changes of psychological distress and quality of life in these patient groups. Methods Patients with conservatively managed (CM) or operated (OM) meningiomas and excellent neurological status, who were screened for psychological distress during the follow-up visit (t1), were included. We performed a follow-up mail/telephone-based survey 3–6 months (t2) after t1. Distress was measured using Hospital Anxiety and Depression Scale (HADS), Distress Thermometer (DT), 36-item Short Form (SF-36), and Brief Fatigue Inventory (BFI). Results Sixty-two patients participated in t1 and 47 in t2. The number of patients reporting increased or borderline values remained high 3 months after initial presentation, with n = 25 (53%) of patients reporting increased anxiety symptom severity and n = 29 (62%) reporting increased depressive symptom severity values. The proportion of distressed patients according to a DT score remained similar after 3 months. Forty-four percent of patients reported significant distress in OM and 33% in CM group. The most common problems among distressed patients were fatigue (t2 75%) and worries (t2 50%), followed by pain, sleep disturbances, sadness, and nervousness. Tumor progress was associated with increased depression scores (OR 6.3 (1.1–36.7)). Conclusion The level of psychological distress in asymptomatic meningiomas and postoperative meningiomas with excellent outcome is high. Further investigations are needed to identify and counsel the patients at risk.

scholarly journals Quality of life is decreased in female patients treated for microprolactinoma

2007 ◽  
Vol 157 (2) ◽  
pp. 133-139 ◽  
Author(s):  
M Kars ◽  
A A van der Klaauw ◽  
C S Onstein ◽  
A M Pereira ◽  
J A Romijn
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Nottingham Health Profile ◽  
Depression Scale ◽  
Well Being ◽  
Anxiety And Depression ◽  
Female Patients ◽  
Sf 36 ◽  
The Impact

Objective: Most studies on treatment of microprolactinoma have focused on clinical and biochemical outcome rather than on functional and mental well-being. We evaluated this topic in female patients with microprolactinoma, because other pituitary adenomas are associated with decreased quality of life. Design: We conducted a cross-sectional study. Patients and methods: To assess the impact of treatment for microprolactinoma on subjective well-being, quality of life was investigated in 55 female patients (mean age 45 ± 10 years), treated for microprolactinoma in our center, using four validated, health-related questionnaires: Short-Form-36 (SF-36), Nottingham Health Profile (NHP), Multidimensional Fatigue Inventory (MFI-20), and Hospital Anxiety and Depression Scale (HADS). Patient outcomes were compared with those of 183 female controls with equal age distributions. Results: Anxiety and depression scores were increased when compared with controls for all subscales as measured by HADS, and fatigue for all but one subscale as measured by MFI-20. Patients treated for microprolactinoma had worse scores on social functioning, role limitations due to physical problems (SF-36), energy, emotional reaction, and social isolation (NHP) when compared with control subjects. Important independent predictors of quality of life were reproductive status and anxiety and depression scores according to the HADS. Conclusion: Quality of life is impaired in female patients treated for microprolactinoma, especially due to increased anxiety and depression. These increased anxious and depressive feelings might be due to possible effects of hyperprolactinemia on the central nervous system. Failure to recognize this association may adversely affect patient–doctor relationships.

Can COV Direct: Effectiveness of a tele-medicine self- care interventions for cancer survivors during COVID 19 pandemic.

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 1583-1583
Author(s):  
Narayanankutty Edavalath Warrier ◽  
Uma V Sankar ◽  
Sreedharan P. S. ◽  
Prasanth V. Parameswaran ◽  
Sajeevan K. V. ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Survivors ◽  
Primary Outcome ◽  
Short Form ◽  
Self Care ◽  
Depression Scale ◽  
Anxiety Symptoms ◽  
Anxiety And Depression ◽  
P Value

1583 Background: Good mental health improves the overall quality of life. Anxiety and depression in post-treatment cancer survivors is common and can affect adversely on the individual. CanCovDirect is a novel, tele-medicine self-care intervention for cancer survivors. We practiced a randomized controlled superiority trial to compare CanCovDirect with usual standard care (SC) in this population.Methods: Individuals completing cancer treatment within the past 3 years who had symptoms with or without anxiety or depression were recruited from clinical and community settings in Northern Kerala. We allocated the participants using block randomization (CanCovDirect plus SC or to SC alone). Assessments of anxiety and depression severity (Centre for Epidemiological Studies-Depression scale [CES-D]; primary outcome) and secondary outcomes anxiety symptoms (Hospital Anxiety and Depression Scale) health-related quality of life (Short Form Survey-12 mental and physical component summaries), were conducted at baseline, as well as 3 and 6 months (primary time point). Analyses of outcomes were adjusted for covariates using linear regression. Results: Participants recruited between June 2020 and November 2020 were randomly assigned to CanCovDirect (n = 152) or SC (n = 152). Among 350 participants randomly assigned, 304 (86.85%) completed the primary outcome at 6 months. CanCovDirect participants reported less severe anxiety and depressive symptoms on the CES-D than SC participants at 6 months, adjusted effect size (ES) 1.68 (95% CI, 1.28 to 2.05). CanCovDirect participants also had significantly greater quality of life compared with SC. Exploratory analysis suggested that types of cancer was a modifier of the primary outcome (interaction term P value =.04); the intervention was effective in women (ES, 0.62; 95% CI, −0.45 to 0.89). Conclusions: CanCovDirect is an essential method of managing mild-moderate depression and anxiety symptoms in cancer survivors.

scholarly journals ASSOCIATION BETWEEN ANXIETY AND DEPRESSION AND QUALITY OF LIFE OF CHRONIC RENAL PATIENTS ON HEMODIALYSIS

2016 ◽  
Vol 25 (3) ◽  
Author(s):  
Ana Carolina Ottaviani ◽  
Loren Carolina Betoni ◽  
Sofia Cristina Iost Pavarini ◽  
Karina Gramani Say ◽  
Marisa Silvana Zazzetta ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Kidney Disease ◽  
Negative Correlation ◽  
Short Form ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Cross Sectional

ABSTRACT To analyze the relationship between anxiety and depression and quality of life in chronic renal failure patients on hemodialysis. This is a correlational study with a cross-sectional, quantitative approach, conducted with 100 kidney patients under treatment at a Renal Replacement Therapy Unit in the state of São Paulo. Data were collected using a sociodemographic questionnaire, Hospital Anxiety and Depression Scale and Kidney Disease and Quality of Life Short-Form. A negative correlation was found between anxiety and depression and the quality of life domains. In addition, the average scores on the Kidney Disease and Quality of Life Short-Form were significantly lower in patients with anxiety and depressive symptoms. In conclusion, there is a negative correlation between depression and anxiety and the health-related quality of life of chronic renal failure patients on hemodialysis.

scholarly journals The effects of physical activity on anxiety, depression, and quality of life in elderly people living in the community

2019 ◽  
Vol 41 (1) ◽  
pp. 36-42 ◽  
Author(s):  
Lucineide da Silva Santos Castelo Branco de Oliveira ◽  
Edila C. Souza ◽  
Rosilene Andrade Silva Rodrigues ◽  
Carlos Alexandre Fett ◽  
Angelo Biagini Piva
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Elderly People ◽  
Protective Factor ◽  
Short Form ◽  
Depression Scale ◽  
The Elderly ◽  
Physical Activities ◽  
Anxiety And Depression

Abstract Introduction: Health problems may negatively affect the psychological and physical aspects of life, influencing the quality of life of older adults. The objective of this study was to analyze the effects of physical activity on quality of life, anxiety, and depression in the elderly population. Methods: We performed a cross-sectional study of 200 elderly people of both genders. Subjects were divided into two groups: one with 100 senior citizens engaged in physical activities in a social center for the elderly; and another composed of 100 subjects who lived in the community but were not engaged in physical activities. The instruments used to assess physical activities, quality of life, and anxiety and depression were, respectively: the modified Baecke questionnaire; the 36-Item Short Form Health Survey (SF-36); and the Hospital Anxiety and Depression Scale (HADS). The data were analyzed using the Student's t test, Pearson's r, and analysis of variance (ANOVA), with odds ratio and a 5% significance level (p<0.05). Results: We observed that the active group showed higher scores of physical activity and quality of life. Conversely, the sedentary group revealed higher scores of anxiety and depression. Data assessment revealed a strong correlation between the domains quality of life, level of vitality, and mental health (r=0.77). The prevalence ratio showed that physical activity is a protective factor against anxiety and depression in the elderly. Conclusion: The findings suggest a correlation between low levels of physical activity and symptoms of anxiety and depression in the elderly living in the community.

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