scholarly journals A Challenge of COVID—19: Associated Infective Endocarditis with Streptococcus gordonii in a Young Immunocompetent Patient

Medicina ◽  
2021 ◽  
Vol 57 (12) ◽  
pp. 1298
Author(s):  
Manuela Arbune ◽  
Alina-Viorica Iancu ◽  
Gabriela Lupasteanu ◽  
Mihaela-Camelia Vasile ◽  
Victorita Stefanescu
Keyword(s):  
Infective Endocarditis ◽  
Human Microbiome ◽  
Immunocompetent Patient ◽  
Streptococcus Gordonii ◽  
Rt Pcr ◽  
Dental Biofilm ◽  
Smell Disorders ◽  
Articular Pain ◽  
Taste And Smell ◽  
Febrile Syndrome

The COVID-19 pandemic is a new challenge for the diagnosis and treatment of infective endocarditis (IE). Fever and other unspecific symptoms of coronaviral infection could be misleading or masking its manifestations. We present the case of a young patient admitted for persistent fever, profuse sweating, headache, articular pain, myalgias, and weight loss. She reported regression taste and smell disorders compared to a month earlier when diagnosed with moderate COVID-19 pneumonia. While the RT-PCR SARS-COV-2 test was positive, she was admitted to a COVID-19 ward. Investigations of febrile syndrome revealed two positive blood cultures with Streptococcus gordonii and the presence of vegetations on the aortic valve, supporting a certain diagnosis of IE. After six weeks of antibiotic treatment, the patient had clinical and biologic favorable outcomes. Streptococcus gordonii is a common commensal related to the dental biofilm, although there were no caries in our patient. The influence of COVID-19 infection on the human microbiome by modifying the virulence of some commensal germs may be a risk factor for IE pathogenesis on native valves and requires the vigilance of clinicians for suspicion of this disease.

scholarly journals Intracranial bleeding (ICB) as a catastrophic complication of Streptococcus gordonii infective endocarditis (IE) in an immunocompetent patient

2018 ◽  
pp. bcr-2018-225265
Author(s):  
Mohd Shakirin Pairan ◽  
Nurashikin Mohammad ◽  
Sanihah Abdul Halim ◽  
Wan Syamimee Wan Ghazali
Keyword(s):  
Infective Endocarditis ◽  
Late Onset ◽  
Mass Effect ◽  
Immunocompetent Patient ◽  
Interesting Case ◽  
Vascular Complication ◽  
Intracranial Bleeding ◽  
Streptococcus Gordonii ◽  
Ct Angiogram ◽  
Ct Brain

We present an interesting case of late-onset intracranial bleeding (ICB) as a complication of Streptococcus gordonii causing infective endocarditis. A previously healthy young woman was diagnosed with infective endocarditis. While she was already on treatment for 2 weeks, she had developed seizures with a localising neurological sign. An urgent non-contrasted CT brain showed massive left frontoparietal intraparenchymal bleeding. Although CT angiogram showed no evidence of active bleeding or contrast blush, massive ICB secondary to vascular complication of infective endocarditis was very likely. An urgent decompressive craniectomy with clot evacuation was done immediately to release the mass effect. She completed total 6 weeks of antibiotics and had postoperative uneventful hospital stay despite having a permanent global aphasia as a sequel of the ICB.

scholarly journals Study of the sensitivity and specificity of smell and taste disorders as a predictive factor of SARS-CoV-2 infection among primary care healthcare professionals

BJGP Open ◽  
2022 ◽  
pp. BJGPO.2021.0141
Author(s):  
Anna Ruiz-Comellas ◽  
Pere Roura Poch ◽  
Glòria Sauch Valmaña ◽  
Víctor Guadalupe-Fernández ◽  
Jacobo Mendioroz Peña ◽  
...  
Keyword(s):  
Sensitivity And Specificity ◽  
Clinical Symptoms ◽  
Strong Predictor ◽  
Area Under The Curve ◽  
Low Grade ◽  
Predictive Values ◽  
Standard Value ◽  
Taste Disorders ◽  
Smell Disorders ◽  
Taste And Smell

Backgroundamong the manifestations of COVID-19 are Taste and Smell Disorders (TSDs).AimThe aim of the study is to evaluate the sensitivity and specificity of TSDs and other associated symptoms to estimate predictive values for determining SARS-CoV-2 infection.Design and settingRetrospective observational study.Methodsa study of the sensitivity and specificity of TSDs has been carried out using the Polymerase Chain Reaction (PCR) test for the diagnosis of SARS-CoV-2 as the Gold Standard value. Logistic regressions adjusted for age and sex were performed to identify additional symptoms that might be associated with COVID-19.Resultsthe results are based on 226 healthcare workers with clinical symptoms suggestive of COVID-19, 116 with positive PCR and 111 with negative PCR. TSDs had an OR of 12.43 (CI 0.95 6.33–26.19), sensitivity 60.34% and specificity 89.09%. In the logistic regression model, the association of TSD, fever or low-grade fever, shivering, dyspnoea, arthralgia and myalgia obtained an area under the curve of 85.7% (CI 0.95: 80.7 % - 90.7 %), sensitivity 82.8 %, specificity 80% and positive predictive values 81.4% and negative 81.5%.ConclusionsTSDs are a strong predictor of COVID-19. The association of TSD, fever, low-grade fever or shivering, dyspnoea, arthralgia and myalgia correctly predicts 85.7% of the results of the COVID-19 test.

Streptococcus gordonii-associated infective endocarditis in a girl with Barlow’s mitral valve disease

2019 ◽  
Vol 29 (8) ◽  
pp. 1099-1100
Author(s):  
Roman R. Komorovsky ◽  
Oksana R. Boyarchuk ◽  
Vira O. Synytska
Keyword(s):  
Differential Diagnosis ◽  
Infective Endocarditis ◽  
Mitral Valve ◽  
Blood Culture ◽  
Positive Blood Culture ◽  
Mitral Valve Disease ◽  
Valve Disease ◽  
Streptococcus Gordonii ◽  
Rheumatic Carditis

AbstractWe present a case of infective endocarditis caused by Streptococcus gordonii in an 11-year-old girl with Barlow’s mitral valve disease. The differential diagnosis of rheumatic carditis and infective endocarditis was difficult as the patient fulfilled the Jones criteria. Vegetation on the mitral valve which became evident later in course of the disease and positive blood culture allowed diagnosing “definite” infective endocarditis.

scholarly journals Culture of the Aspirated Coronary Thromboembulus Specimen: A Peculiar Diagnostic Method for Infective Endocarditis

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Massimo Slavich ◽  
Andrea Fisicaro ◽  
Eustachio Agricola ◽  
Giovanni Coppi ◽  
Carlo Ballarotto ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Infective Endocarditis ◽  
Hospital Stay ◽  
Transesophageal Echocardiography ◽  
Diagnostic Method ◽  
Definitive Diagnosis ◽  
Clinical Scenario ◽  
Persistent Fever ◽  
Coronary Syndrome ◽  
Articular Pain

A 69-year-old man was admitted to our hospital for persistent fever, myalgias, articular pain, headache, and hypoaesthesia of the scalp. The clinical scenario was typical for giant-cell arteritis. During hospital stay, patient developed fugax amaurosis, stroke, and acute coronary syndrome. The definitive diagnosis of infective endocarditis, supported by transesophageal echocardiography, was confirmed only by culturing the material obtained during angiography and coronary thromboaspiration.

scholarly journals Infective Endocarditis Caused by Rhodococcus equi in an Immunocompetent Patient

Cureus ◽  
2020 ◽  
Author(s):  
Rony Shah ◽  
Linda C Klumpp ◽  
Nishant Nerella ◽  
Gustine Liu-Young ◽  
Jeffrey Jordan
Keyword(s):  
Infective Endocarditis ◽  
Immunocompetent Patient ◽  
Rhodococcus Equi

scholarly journals Main symptoms in patients presenting in the COVID-19 period

2020 ◽  
Vol 65 (4) ◽  
pp. 127-132 ◽  
Author(s):  
Aylin Çalıca Utku ◽  
Gökçen Budak ◽  
Oğuz Karabay ◽  
Ertuğrul Güçlü ◽  
Hüseyin Doğuş Okan ◽  
...  
Keyword(s):  
Respiratory Symptoms ◽  
Negative Group ◽  
Positive Group ◽  
Taste Disorder ◽  
First Case ◽  
Training And Research ◽  
Novel Coronavirus ◽  
Smell Disorders ◽  
University Training ◽  
Taste And Smell

Background The first case of a novel coronavirus (COVID-19) infection was detected in Wuhan, fever and respiratory symptoms have been frequently reported in patients infected with this virus. Aim It was aimed to compare the symptoms of patients with COVID-19 positivity and patients without COVID-19 positivity hospitalized with suspicion of COVID-19. Methods Patients presenting to the Sakarya University Training and Research Hospital with suspicion of COVID-19 were included in the study. Samples were obtained from the patients and PCR tests were performed; the patients were grouped as COVID-19 positive and COVID-19 negative; these two groups were questioned for 15 symptoms and the results were compared. Results A total of 297 patients with suspicion of COVID-19 were included in the study. COVID-19 was positive in 143 patients and negative in 154 patients. The most common symptoms in the COVID-19 positive group were: cough (56.6%), weakness (56.6%), taste disorder (35.7%), myalgia (34.3%), and fever (33.6%); and in the COVID-19 negative group: cough (63%), weakness (45.5%), dyspnea (29.9%), headache (27.3%) and fever (24.7%). When these two groups were compared, taste disorder, smell disorder and diarrhea were significantly higher in the COVID-19 positive group (p = <0,00001, p = 0,00001 and p = 0,02). Conclusion Our study showed that taste and smell disorders and diarrhea were important markers in COVID-19 infection.

scholarly journals Shear-Enhanced Oral Microbial Adhesion

2009 ◽  
Vol 76 (4) ◽  
pp. 1294-1297 ◽  
Author(s):  
Albert M. Ding ◽  
Robert J. Palmer ◽  
John O. Cisar ◽  
Paul E. Kolenbrander
Keyword(s):  
Sialic Acid ◽  
Infective Endocarditis ◽  
Streptococcus Gordonii ◽  
Microbial Adhesion

ABSTRACT Shear-enhanced adhesion, although not observed for fimbria-mediated adhesion of oral Actinomyces spp., was noted for Hsa-mediated adhesion of Streptococcus gordonii to sialic acid-containing receptors, an interaction implicated in the pathogenesis of infective endocarditis.

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