scholarly journals Dissipation Dynamics and Dietary Risk Assessment of Kresoxim-Methyl Residue in Rice

Molecules ◽  
2019 ◽  
Vol 24 (4) ◽  
pp. 692
Author(s):  
MingNa Sun ◽  
Lu Yu ◽  
Zhou Tong ◽  
Xu Dong ◽  
Yue Chu ◽  
...  

Kresoxim-methyl is a high-efficiency and broad-spectrum fungicide used for the control of rice fungal diseases; however, its residues after application potentially threaten human health. Investigations on the dissipation of kresoxim-methyl residue in rice field systems and dietary risk assessment of kresoxim-methyl in humans are limited. The present study employed the QuEChERS-GC-MS/MS method for residue analysis of kresoxim-methyl in rice plants, brown rice, and rice husks. The samples were extracted with acetonitrile and purified by PSA, C18 column, and GCB. The average recovery of the spiked target compounds in the three matrices was between 80.5% and 99.3%, and the RSD was between 2.1% and 7.1%. The accuracy and precision of the method is in accordance with the requirements of residue analysis methods. Dissipation dynamic testing of kresoxim-methyl in rice plants indicated a half-life within the range of 1.8–6.0 days, and a rapid dissipation rate was detected. Dietary intake risk assessment showed that the national estimated daily intake (NEDI) of kresoxim-methyl in various Chinese subpopulations was 0.022–0.054 μg/(kg bw·days), and the risk quotient (RQ) was 0.0000055–0.00014%. These findings indicate that the risk for chronic dietary intake of kresoxim-methyl in brown rice is relatively low. The present study provides information and theoretical basis for guiding the scientific use of kresoxim-methyl in rice fields and evaluating its dietary risk in brown rice.

2017 ◽  
Vol 52 (4) ◽  
pp. 256-266 ◽  
Author(s):  
Darío A. Maggioni ◽  
Marcelo L. Signorini ◽  
Nicolás Michlig ◽  
María R. Repetti ◽  
Mirna E. Sigrist ◽  
...  

Toxics ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 249
Author(s):  
Sebastian Elgueta ◽  
Marcela Valenzuela ◽  
Marcela Fuentes ◽  
Pilar Ulloa ◽  
Cecilia Ramos ◽  
...  

In recent years, the official authorities in Chile have reported transgressions in the maximum residue levels of pesticides in fresh vegetables. There is no official information about traceability, pesticide levels, and potential health risks. The aim of this study was to analyse pesticide residues and their corresponding dietary risk assessments in tomatoes from supermarkets in the Metropolitan Region. Pesticides were extracted using the Quick, Easy, Cheap, Effective, Rugged and Safe, QuEChERS method, and their concentrations were determined by using chromatography with HPLC-FL/UV and GC-MS/ECD/NPD, following the Analytical Quality Control and Method Validation Procedures for Pesticides Residues Analysis in Food and Feed, SANTE guide and ISO 17025:2017 standard. In addition, a dietary risk assessment was carried out by comparing Chilean data to international references. The results reported that 9% of the samples had pesticide residue levels above the maximum residue levels permitted in Chile. All the scenarios evaluated revealed the highest estimated daily intake and hazard quotients for methamidophos and chlorpyrifos. Both the active substances used were acetylcholinesterase inhibitors and were neurotoxic under chronic risk assessment. The results showed the highest chronic hazard index in the Chilean scenario for all age groups and genders. The evidence obtained revealed that methamidophos, methomyl, and chlorpyrifos should be restricted for their use in Chilean agriculture.


Molecules ◽  
2021 ◽  
Vol 27 (1) ◽  
pp. 188
Author(s):  
Agnieszka Zapaśnik ◽  
Marcin Bryła ◽  
Agnieszka Waśkiewicz ◽  
Edyta Ksieniewicz-Woźniak ◽  
Grażyna Podolska

The aim of this study was to estimate the contamination of grain coffee, roasted coffee, instant coffee, and cocoa purchased in local markets with ochratoxin A (OTA) and its isomerization product 2′R-ochratoxin A (2′R-OTA), and to assess risk of dietary exposure to the mycotoxins. OTA and 2′R-OTA content was determined using the HPLC chromatography with immunoaffinity columns dedicated to OTA. OTA levels found in all the tested samples were below the maximum limits specified in the European Commission Regulation EC 1881/2006. Average OTA concentrations calculated for positive samples of grain coffee/roasted coffee/instant coffee/cocoa were 0.94/0.79/3.00/0.95 µg/kg, with the concentration ranges: 0.57–1.97/0.44–2.29/0.40–5.15/0.48–1.97 µg/kg, respectively. Average 2′R-OTA concentrations calculated for positive samples of roasted coffee/instant coffee were 0.90/1.48 µg/kg, with concentration ranges: 0.40–1.26/1.00–2.12 µg/kg, respectively. In turn, diastereomer was not found in any of the tested cocoa samples. Daily intake of both mycotoxins with coffee/cocoa would be below the TDI value even if the consumed coffee/cocoa were contaminated with OTA/2′R-OTA at the highest levels found in this study. Up to now only a few papers on both OTA and 2′R-OTA in roasted food products are available in the literature, and this is the first study in Poland.


2021 ◽  
Vol 98 ◽  
pp. 103839
Author(s):  
Beata Czarczyńska-Goślińska ◽  
Tomasz Grześkowiak ◽  
Robert Frankowski ◽  
Janina Lulek ◽  
Jan Pieczak ◽  
...  

2021 ◽  
Vol 350 ◽  
pp. 129245
Author(s):  
Yan Tao ◽  
Chunhong Jia ◽  
Junjie Jing ◽  
Jinwei Zhang ◽  
Pingzhong Yu ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document