scholarly journals Analysis of the Overlapped Electrochemical Signals of Hydrochlorothiazide and Pyridoxine on the Ethylenediamine-Modified Glassy Carbon Electrode by Use of Chemometrics Methods

Molecules ◽  
2019 ◽  
Vol 24 (14) ◽  
pp. 2536 ◽  
Author(s):  
Yue Zhang ◽  
Yan Zhou ◽  
Shujun Chen ◽  
Yashi You ◽  
Ping Qiu ◽  
...  
Keyword(s):  
Least Squares ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Principal Component ◽  
Potential Range ◽  
Carbon Electrode ◽  
Separation And Purification ◽  
Modified Glassy Carbon Electrode ◽  
Buffer Solution ◽  
Experimental Conditions

In this work, the electrochemical behavior of hydrochlorothiazide and pyridoxine on the ethylenediamine-modified glassy carbon electrode were investigated by differential pulse voltammetry. In pH 3.4 Britton-Robinson (B-R) buffer solution, both hydrochlorothiazide and pyridoxine had a pair of sensitive irreversible oxidation peaks, that overlapped in the 1.10 V to 1.20 V potential range. Under the optimum experimental conditions, the peak current was linearly related to hydrochlorothiazide and pyridoxine in the concentration range of 0.10–2.0 μg/mL and 0.02–0.40 μg/mL, respectively. Chemometrics methods, including classical least squares (CLS), principal component regression (PCR) and partial least squares (PLS), were introduced to resolve the overlapped signals and determine the two components in mixtures, which avoided the troublesome steps of separation and purification. Finally, the simultaneous determination of the two components in commercial pharmaceuticals was performed with satisfactory results.

Preparation and characterization of a poly-o-phenylenediamine film modified glassy carbon electrode as a H2O2 sensor

2013 ◽  
Vol 91 (11) ◽  
pp. 1077-1084 ◽  
Author(s):  
Wenying Zhai ◽  
Xiuying Tian ◽  
Yun Yan ◽  
Yuehua Xu ◽  
Yuechun Zhao ◽  
...  
Keyword(s):  
Cyclic Voltammetry ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Electrochemical Impedance ◽  
Monomer Concentration ◽  
Acetate Buffer ◽  
Acetate Buffer Solution ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Buffer Solution

A poly-o-phenylenediamine film modified glassy carbon electrode (PoPD/GC) was successfully prepared by cyclic voltammetry in acetate buffer solution. The polymerization mechanism of oPD is discussed. The impedance behavior and morphology of the PoPD membrane were characterized using cyclic voltammetry, electrochemical impedance spectroscopy, and scanning electron microscopy, respectively. It is discovered that the PoPD/GC prepared only in acetate buffer solution had dual electrocatalytic activity toward the oxidation and reduction of H2O2. The optimal buffer solution pH, scanning rate, monomer concentration, and number of scannings for film forming were 4.2, 0.05 V s−1, 6.0 mmol L−1, and 30, respectively. The linear ranges between the anodic (Δia) or cathodic (Δic) current and H2O2 concentration were 0.07−1.0 × 104 and 0.04−4.5 × 104 μmol L−1, respectively. The corresponding calibration curves were Δia (μA) = 8.03c (mmol L−1) + 6.36 (n = 18, R2 = 0.9989) and Δic (μA) = −5.52c (mmol L−1) − 0.77 (n = 18, R2 = 0.9990) with a detection limit of 0.03 and 0.02 μmol L−1 (S/N = 3), respectively. The PoPD/GC prepared in the optimal conditions showed good stability and quick response (<0.2 s) to H2O2, which was successfully applied to the determination of H2O2 in real water samples with satisfactory results.

scholarly journals Determination of Mercury (II) Ion on Aryl Amide-Type Podand-Modified Glassy Carbon Electrode

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Sevgi Güney ◽  
Gülcemal Yıldız ◽  
Gönül Yapar
Keyword(s):  
Glassy Carbon Electrode ◽  
Modified Electrode ◽  
Glassy Carbon ◽  
Reference Electrode ◽  
Differential Pulse ◽  
Acetate Buffer Solution ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Buffer Solution

A new voltammetric sensor based on an aryl amide type podand, 1,8-bis(o-amidophenoxy)-3,6-dioxaoctane, (AAP) modified glassy carbon electrode, was described for the determination of trace level of mercury (II) ion by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). A well-defined anodic peak corresponding to the oxidation of mercury on proposed electrode was obtained at 0.2 V versus Ag/AgCl reference electrode. The effect of experimental parameters on differential voltammetric peak currents was investigated in acetate buffer solution of pH 7.0 containing 1 × 10−1 mol L−1NaCl. Mercury (II) ion was preconcentrated at the modified electrode by forming complex with AAP under proper conditions and then reduced on the surface of the electrode. Interferences of Cu2+, Pb2+, Fe3+, Cd2+, and Zn2+ions were also studied at two different concentration ratios with respect to mercury (II) ions. The modified electrode was applied to the determination of mercury (II) ions in seawater sample.

Electroanalysis of nicotine at an electroreduced carboxylated graphene modified glassy carbon electrode

2015 ◽  
Vol 7 (3) ◽  
pp. 1147-1153 ◽  
Author(s):  
Hualing Xiao ◽  
Lingen Sun ◽  
Hongling Yan ◽  
Wen Wang ◽  
Jiali Liu ◽  
...  
Keyword(s):  
Cyclic Voltammetry ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Phosphate Buffer ◽  
Phosphate Buffer Solution ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Buffer Solution

Nicotine is determined at a glassy carbon electrode modified with partially electroreduced carboxylated graphene by cyclic voltammetry and semi-derivative treatment after enrichment at −1.1 V in 0.1 M pH 7.0 phosphate buffer solution.

Electrochemical Determination of Paracetamol at Poly(3-Methylthiophene)/Reduced Graphene Oxide Modified Glassy Carbon Electrode

NANO ◽  
2018 ◽  
Vol 13 (09) ◽  
pp. 1850104 ◽  
Author(s):  
Caiwei Li ◽  
Weimeng Si ◽  
Yuting Wu ◽  
Cheng Zhang ◽  
Wu Lei ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Limit Of Detection ◽  
Differential Pulse ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Buffer Solution ◽  
Reduced Graphene

Poly(3-methylthiophene)/reduced graphene oxide (P3MT/RGO) modified glassy carbon electrode (GCE) was fabricated via a facile procedure. P3MT was directly electrodeposited on the RGO coated electrode and employed for the electrochemical detection of paracetamol (PCT). The morphology of composite was characterized by scanning electron microscopy (SEM). Cyclic voltammetry (CV) and differential pulse voltammetry (DPV) were used to investigate the electrochemical behaviors of PCT on P3MT/RGO/GCE. Experimental parameters, such as the scan rates, polymerization laps and the pH of buffer solution were optimized. Under the optimal conditions, the anodic peak current in DPVs varies linearly with the concentration of PCT, and the limit of detection was 0.025[Formula: see text][Formula: see text]M. Moreover, the proposed P3MT/RGO/GCE also exhibited superior stability and reproducibility.

Electrochemical Sensor for the Detection of Dopamine in the Presence of Ascorbic Acid in Neutral pH on Graphitized Nanoporous Carbon Modified Glassy Carbon Electrode

2012 ◽  
Vol 584 ◽  
pp. 334-338
Author(s):  
Rajendiran Thangaraj ◽  
Muringah Kandy Mufeedah ◽  
Annamalai Senthil Kumar
Keyword(s):  
Ascorbic Acid ◽  
Glassy Carbon Electrode ◽  
Modified Electrode ◽  
Glassy Carbon ◽  
Nanoporous Carbon ◽  
Carbon Electrode ◽  
Oxidation Peak ◽  
Modified Glassy Carbon Electrode ◽  
Buffer Solution ◽  
Neutral Ph

Selective detection of dopamine (DA) in presence of ascorbic (AA) is an important analytical problem, due to its combined existence in the biological system. In the present study, we are reporting an electrochemical detection method for dopamine (DA) in the presence of ascorbic acid (AA) using graphitized nanoporous carbon (NPC) modified glassy carbon electrode (GCE/NPC) in 0.1 M phosphate buffer solution. The modified electrode shows excellent electrocatalytic activities towards the oxidations of DA and AA in neutral pH buffer solution. Compared to unmodified GCE, GCE/NPC shows well separated and enhanced oxidation peak currents. Differential pulse voltammetric technique used as qualitative analytical tool for the detection of DA. The oxidation peak potentials for DA and AA were at -80 and 136 mV vs Ag/AgCl respectively. The modified electrode shows good stability and reproducibility with the relative standard deviation value of 2.6 %. The analytical application of the modified electrode (GCE/NPC) was demonstrated for the individual determination of DA in clinical injection and pharmaceutical tablet by using standard addition method.

Sensitive Electrochemical Determination of Rhodamine B Based on a Silica-Pillared Zirconium Phosphate/Nafion Composite Modified Glassy Carbon Electrode

2016 ◽  
Vol 99 (3) ◽  
pp. 760-765 ◽  
Author(s):  
Jing Zhang ◽  
Liu Zhang ◽  
Wenchang Wang ◽  
Zhidong Chen
Keyword(s):  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Rhodamine B ◽  
Zirconium Phosphate ◽  
Layer Structure ◽  
Electrochemical Determination ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Experimental Conditions

Abstract A sensitive and convenient electrochemical method was developed for the determination of rhodamine B by a silica-pillared zirconium phosphate/nafion composite (SPZP/NAF) modified glassy carbon electrode. The SPZP was characterized with scanning electron microscopy and X-ray diffraction. Because of the layer structure and large specific surface area of SPZP, the SPZP/NAF modified glassy carbon electrode showed high electrocatalytic activity toward the oxidation of rhodamine B. Under optimal experimental conditions, the SPZP/NAF modified electrode exhibited a wide linear response to rhodamine B ranging from 0.01 to 5.0 μM and a low detection limit down to 4.3 nM (S/N = 3). This method showed good accuracy, acceptable precision, and reproducibility. This electrode had been applied in the determination of rhodamine B in preserved fruit and chili powder samples. The proposed method provided a useful tool for the assay of rhodamine B in food samples.

Electrochemical Behaviours of Scutellarin at Multi-Wall Carbon Nanotubes Modified Glassy Carbon Electrode

2012 ◽  
Vol 602-604 ◽  
pp. 239-242
Author(s):  
Zhuo Cai ◽  
Wei Chao Yue ◽  
Jing Ni Gan ◽  
Yue Peng ◽  
Xiao Liang He
Keyword(s):  
Glassy Carbon Electrode ◽  
Glassy Carbon ◽  
Enhancement Effect ◽  
Carbon Electrode ◽  
Modified Glassy Carbon Electrode ◽  
Buffer Solution ◽  
Solution Ph ◽  
Multi Wall Carbon Nanotubes ◽  
Electroanalytical Method

A multi-wall carbon nanotube modified glassy carbon electrode (MWCNTs/GCE) has been prepared. The electrochemical behavior of scutellarin at the modified electrode and its electroanalytical method have been studied. It was showed that in 0.20 mol/L Na2HPO4-NaH2PO4 buffer solution (pH=7.4) MWCNTs/GCE exhibited excellent catalytic and enhancement effect on the electrochemical oxidation of scutellarin, the sensitivity increaced 23 times compared with that at bare GCE. The measurement parameters were optimized. Under the optimal conditions, the linear range of scutellarin concentration was 4.0×10-6-1.0×10-4 mol/L (R=0.9991) with a detection limit of 8.2×10-7 mol/L(S/N =3), and the RSD for 4.0×10-5 mol/L scutellarin solution was 1.8% (n=11). This method was successfully used in the determination of scutellarin in injection and tablets.

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