scholarly journals Antifungal and Surface Properties of Chitosan-Salts Modified PMMA Denture Base Material

Molecules ◽  
2020 ◽  
Vol 25 (24) ◽  
pp. 5899
Author(s):  
Katarzyna Walczak ◽  
Georg Schierz ◽  
Sabine Basche ◽  
Carola Petto ◽  
Klaus Boening ◽  
...  
Keyword(s):  
Surface Properties ◽  
Base Material ◽  
Dependent Manner ◽  
Denture Base ◽  
Antifungal Effect ◽  
Denture Stomatitis ◽  
Antifungal Properties ◽  
Chitosan Hydrochloride ◽  
Pmma Resin

Chitosan (CS) and its derivatives show antimicrobial properties. This is of interest in preventing and treating denture stomatitis, which can be caused by fungi. Therefore, the aim of this study was the development of a novel antifungal denture base material by modifying polymethyl methacrylate (PMMA) with CS-salt and characterizing its antifungal and surface properties in vitro. For this purpose, the antifungal effect of chitosan-hydrochloride (CS-HCl) or chitosan-glutamate (CS-G) as solutions in different concentrations was determined. To obtain modified PMMA resin specimens, the CS-salts were added to the PMMA before polymerization. The roughness of these specimens was measured by contact profilometry. For the evaluation of the antifungal properties of the CS-salt modified resins, a C. albicans biofilm assay on the specimens was performed. As solutions, both the CS-G and CS-HCl-salt had an antifungal effect and inhibited C. albicans growth in a dose-dependent manner. In contrast, CS-salt modified PMMA resins showed no significant reduced C. albicans biofilm formation. Furthermore, the addition of CS-salts to PMMA significantly increased the surface roughness of the specimens. This study shows that despite the antifungal effect of CS-salts in solution, a modification of PMMA resin with these CS-salts does not improve the antifungal properties of PMMA denture base material.

Adhesion of Candida to Vanillin-Coated PMMA Resin

2017 ◽  
Vol 909 ◽  
pp. 171-176 ◽  
Author(s):  
Sroisiri Thaweboon ◽  
Boonyanit Thaweboon ◽  
Rattiporn Kaypetch
Keyword(s):  
Base Material ◽  
Negative Control ◽  
Yeast Cells ◽  
Adhesion Assay ◽  
Dependent Manner ◽  
Denture Base ◽  
Coating Agent ◽  
Denture Stomatitis ◽  
Clinical Disorder ◽  
Pmma Resin

Denture stomatitis is a common clinical disorder seen among denture wearers. Candida albicans is considered to be the major cause which can adhere to and colonize the surface of denture base material made of polymethyl methacrylate (PMMA) resin. This study aims to investigate the effect of vanillin-coated PMMA resin on the adhesion of C. albicans. Heat-polymerized PMMA resin (Vertex RS, Dentimex, Netherlands) samples were prepared and coated with vanillin at various concentrations of 7, 11, and 15 mM. Sterile distilled water and 0.2% chlorhexidine gluconate solution were used to coat the surfaces in negative and positive controls, respectively. The adhesion assay was performed with 3 strains of C. albicans based on the method described by Samaranayake and MacFarlane. The numbers of adherent yeast cells on PMMA resin surfaces were counted under microscope by random selection of 20 fields at 400x magnification. It was found that all vanillin-coated PMMA resin samples had significant decrease of candida adhesion (50-90% reduction) compared to the negative control. The effect was observed to be in a dose dependent manner (p<0.05). Chlorhexidine exhibited strong reduction effect (96-98% reduction). In conclusion, coating PMMA resin with 7-15 mM vanillin can inhibit candida adhesion to the surface. With further testing and development, vanillin may be used as coating agent for denture to prevent candida adhesion and reduce risk of denture stomatitis.

In Vitro Evaluation of Candida albicans Biofilm Formation on Denture Base PMMA Resin Incorporated with Silver Nanoparticles and its Effect on Flexural Strength

2014 ◽  
Vol 905 ◽  
pp. 51-55 ◽  
Author(s):  
Sahana Bajracharya ◽  
Sroisiri Thaweboon ◽  
Boonyanit Thaweboon ◽  
Amornrat Wonglamsam ◽  
Theerathavaj Srithavaj
Keyword(s):  
Silver Nanoparticles ◽  
Flexural Strength ◽  
Biofilm Formation ◽  
Base Material ◽  
Bending Test ◽  
Yeast Nitrogen Base ◽  
Nitrogen Base ◽  
Denture Base ◽  
Pmma Resin

The aim of this study is to investigate the candidal biofilm formation on the silver nanoparticles (AgNPs) incorporated denture base heat-polymerized (poly methyl methacrylate), PMMA, resinand its flexural strength.Materials and methods:A total of 36PMMA resin specimens (15×15×2 mm3) were fabricated and divided into 4 groups based on their AgNPs contents (0%,0.5%, 1% and 1.5% w/w of polymer). The biofilm of clinical and reference strainsof C.albicanswere grown on PMMA resin specimens in the presence of yeast nitrogen base broth supplemented with 100 mM glucose at 37oC for 48 h and evaluated by tetrazolium reduction assay. The flexural strength of PMMA resin specimens (65×10×3.3 mm3) were tested by using three-point bending test. Data were analyzed by Kruskal-Wallis and Mann-Whitney U test at p<0.05. result:all="" 3="" groups="" with="" agnps="" showed="" significant="" reduction="" in="" biofilm="" formation="" of="" both="" strains="" i="">C.albicans compared to control (0% AgNPs) (p<0.05). Decreased flexural strength was observed with AgNPs groups compared with the control but within acceptable limit of ISO 20795-1. Conclusion:The reduction of the C. albicans biofilm was observed on the heat-polymerized PMMA resin incorporated with AgNPs. Regarding the flexural strength, the values were within ISO limit. These modified PMMA resin can be developed for the prevention or treatment of the candidal infection associated with the denture base material.

Wear Resistance Evaluation of the Thermoplastic Acetal Resin Denture Base Material – An In Vitro Study

2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Ahmed Alagwany ◽  
Diab Fatoh ◽  
Mohamed Abbas ◽  
Mohamed A. Helal ◽  
Ihab I. Mahmoud
Keyword(s):  
Wear Resistance ◽  
Base Material ◽  
In Vitro Study ◽  
Vitro Study ◽  
Denture Base ◽  
Resistance Evaluation

scholarly journals Effect of incorporation of nanoclay on the properties of heat cure denture base material: An In vitro study

2019 ◽  
Vol 10 (4) ◽  
pp. 658
Author(s):  
AngelMary Joseph ◽  
Suja Joseph ◽  
Nicholas Mathew ◽  
AshwinThomas Koshy ◽  
NamrathaL Jayalakshmi ◽  
...  
Keyword(s):  
Base Material ◽  
In Vitro Study ◽  
Vitro Study ◽  
Denture Base ◽  
Heat Cure

scholarly journals Denture Acrylic Resin Material with Antibacterial and Protein-Repelling Properties for the Prevention of Denture Stomatitis

Polymers ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 230
Author(s):  
Salwa Omar Bajunaid ◽  
Bashayer H. Baras ◽  
Michael D. Weir ◽  
Hockin H. K. Xu
Keyword(s):  
Oral Mucosa ◽  
Pathological Condition ◽  
Base Material ◽  
Acrylic Resin ◽  
Control Group ◽  
Control Groups ◽  
Denture Base ◽  
Denture Stomatitis ◽  
Colony Forming Unit ◽  
Bioactive Agents

Denture stomatitis is a multifactorial pathological condition of the oral mucosa that affects up to 72% of denture wearers. It is commonly seen on the palatal mucosa and characterized by erythema on the oral mucosa that are in contact with the denture surface. The aim of this study was to incorporate 2-methacryloyloxyethyl phosphorylcholine (MPC) and dimethylaminohexadecyl methacrylate (DMAHDM) into a high impact polymethylmethacrylate heat-cured denture base acrylic resin as a potential treatment for denture stomatitis. We used a comparative study design to examine the effect of incorporating MPC as a protein repellent agent and DMAHDM as an antifungal agent to prevent the adherence of Candida albicans to the denture base material. The dual incorporation of MPC and DMAHDM reduced C. albicans biofilm colony-forming unit by two orders of magnitude when compared to the control group devoid of the bioactive agents. Although the addition of MPC and DMAHDM alone or in combination significantly reduced the flexural strength of the material, they showed reduced roughness values when compared to control groups. This new denture acrylic resin provides the benefit of enhancing C. albicans biofilm elimination through dual mechanisms of action, which could potentially reduce the prevalence of denture stomatitis.

Flexural and Surface Properties of PMMA Denture Base Material Modified with Thymoquinone as an Antifungal Agent

2018 ◽  
Vol 29 (3) ◽  
pp. 243-250 ◽  
Author(s):  
Mohammed M. Gad ◽  
Ahmad M. Al‐Thobity ◽  
Shaimaa M. Fouda ◽  
Ritva Näpänkangas ◽  
Aune Raustia
Keyword(s):  
Surface Properties ◽  
Antifungal Agent ◽  
Base Material ◽  
Denture Base

Surface Adherence of Candida albicans to Different Polymethyl Methacrylate Resin Denture Base Materials

2011 ◽  
Vol 2 (3) ◽  
pp. 237-242
Author(s):  
Achut R Devarhubli ◽  
VK Subbarao ◽  
NP Patil
Keyword(s):  
Candida Albicans ◽  
Polymethyl Methacrylate ◽  
Cobalt Alloy ◽  
Denture Base ◽  
Denture Stomatitis ◽  
Base Materials ◽  
Normal Individuals ◽  
Cobalt Chrome Alloy ◽  
Cobalt Chrome

ABSTRACT Over the years researchers have reported on the frequency and distribution of yeast in the oropharynx of apparently normal individuals and those with systemic or mycotic diseases wearing dentures. Few workers have taken into consideration the role played by the legion of denture base materials on the occurrence and progression of denture stomatitis. Hence this study was undertaken with the objective of evaluating the in vitro adherence of Candida albicans to different denture base materials namely reinforced polymethyl methacrylate, Nonreinforced polymethyl methacrylate and Cobalt chrome alloy of which chrome cobalt alloy showed less adherence to candidal cells compared to the two polymethyl methacrylate resins.

Shear Strength of Visible Light Cured-Urethane Dimethacrylate and Polymethylmethacrylate Denture Base Material to Cobalt Chromium Dental Prosthesis: An In-Vitro Study

2017 ◽  
Vol 7 (10) ◽  
pp. 1008-1013
Author(s):  
Abdulaziz M. Albaker ◽  
Faisal M. Fahmi ◽  
Merna F. Fahmi ◽  
Abdullah M. Alfarraj Aldosari ◽  
Ishfaq A. Bukhari ◽  
...  
Keyword(s):  
Shear Strength ◽  
Visible Light ◽  
Base Material ◽  
In Vitro Study ◽  
Dental Prosthesis ◽  
Vitro Study ◽  
Cobalt Chromium ◽  
Denture Base ◽  
Urethane Dimethacrylate
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