scholarly journals Denture Acrylic Resin Material with Antibacterial and Protein-Repelling Properties for the Prevention of Denture Stomatitis

Polymers ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 230
Author(s):  
Salwa Omar Bajunaid ◽  
Bashayer H. Baras ◽  
Michael D. Weir ◽  
Hockin H. K. Xu

Denture stomatitis is a multifactorial pathological condition of the oral mucosa that affects up to 72% of denture wearers. It is commonly seen on the palatal mucosa and characterized by erythema on the oral mucosa that are in contact with the denture surface. The aim of this study was to incorporate 2-methacryloyloxyethyl phosphorylcholine (MPC) and dimethylaminohexadecyl methacrylate (DMAHDM) into a high impact polymethylmethacrylate heat-cured denture base acrylic resin as a potential treatment for denture stomatitis. We used a comparative study design to examine the effect of incorporating MPC as a protein repellent agent and DMAHDM as an antifungal agent to prevent the adherence of Candida albicans to the denture base material. The dual incorporation of MPC and DMAHDM reduced C. albicans biofilm colony-forming unit by two orders of magnitude when compared to the control group devoid of the bioactive agents. Although the addition of MPC and DMAHDM alone or in combination significantly reduced the flexural strength of the material, they showed reduced roughness values when compared to control groups. This new denture acrylic resin provides the benefit of enhancing C. albicans biofilm elimination through dual mechanisms of action, which could potentially reduce the prevalence of denture stomatitis.

Materials ◽  
2021 ◽  
Vol 14 (5) ◽  
pp. 1067
Author(s):  
Salwa O. Bajunaid ◽  
Bashayer H. Baras ◽  
Abdulrahman A. Balhaddad ◽  
Michael D. Weir ◽  
Hockin H. K. Xu

Candida albicans (C. albicans) biofilm is a common etiological factor in denture stomatitis. The purpose of this study was to investigate the effects of incorporating 2-methacryloyloxyethyl phosphorylcholine (MPC) as a protein repellent into a new high-impact denture acrylic (HIPA) resin on the surface roughness, solution pH, and C. albicans biofilm adhesion to the denture base. The new acrylic denture resin base was formulated by mixing MPC into HIPA resin at mass fractions of 1.5%, 3%, and 4.5%. Surface roughness was measured using a Mitutoyo surface roughness tester. C. albicans biofilm growth and viability were assessed via colony forming unit counts. The pH of the biofilm growth medium was measured using a digital pH meter. Adding MPC to the HIPA resin at percentages of 1.5% and 3% increased the roughness values significantly (p < 0.05), while adding 4.5% MPC resulted in no difference in roughness values to that of the control group (p > 0.05). All experimental groups demonstrated neutral pH values (pH ≅ 7) and were not significantly different from each other (p > 0.05). Incorporating 2-methacryloyloxyethyl phosphorylcholine at 4.5% resulted in a significant (≅1 log) colony-forming unit reduction compared with the control group with 0% MPC (p < 0.05). A fungal-retarding denture acrylic resin was developed through the incorporation of MPC for its protein-repelling properties. This newly developed denture acrylic material has the potential to prevent oral microbial infections, such as denture stomatitis.


2019 ◽  
Vol 10 (2) ◽  
pp. 1464-1469
Author(s):  
Adnan R. Al Assal ◽  
Abdalbaset A Fatalla ◽  
Mohammed Moudhaffar ◽  
Ghasak H Jani

The general upgrading of polymer denture base material and research continuously looking for ideal restorative dental material with better properties, adequate esthetic properties, less expensive and easier to handle material to develop photo polymerization dental materials. This study was conducted to evaluate the effect of addition polyamide on mechanical microparticle properties light cure denture base material. One hindered sixty specimens from light-cured acrylic resin (Aurora). The divided mainly into four groups according to test used (Transverse strength test, impact strength test, hardness test and tensile strength test) with 40 specimens for each group. The results show an increase in Transverse strength, impact strength, hardness and tensile strength in all experimental group when compared to control group the highest mean values for all tests included in the study appeared in group B 1% polyamide. The addition of polyamide microparticle improves transverse, tensile, impact strength and hardness properties of denture base material.


2015 ◽  
Vol 3 (2) ◽  
pp. 68-73
Author(s):  
Riezka Hanafiah Putri ◽  
Zulkarnain Agus ◽  
Eni Rahmi

Heat-polymerized  acrylic  resins  is  the  most  used  denture  base  material  in  prosthodontics.  One  of  mechanical properties of acrylic resins is transverse strength. It represents the masticatory pressure that is applied to denture base. Black tea is the second largest consumed beverage in the world. The aim of this study was to investigate the effect of black tea beverage on transverse strength of heat-polymerized acrylic resins. A total of 24 heat-polymerized acrylic resin plates (65×10×2,5 mm) were immersed in black tea beverage for 1, 4, and 20 days as treatment group and in aquadest for 1, 4, and 20 days as control group. The transverse strength of  acrylic samples were measured by three–point bending test by universal testing machine. Data were statistically analyzed using Independent t test. The transverse strength values of acrylic resin immersed in black tea beverage had no significant differences to the transverse strength values of acrylic resin immersed in aquadest with similar immersion time (p>0,05). There was no effect of black tea beverage on transverse strength of heat-polymerized acrylic resins. Immersion time decrease the transverse strength of heat-polymerized acrylic resins due to water sorption. Keywords: Heat-polymerized acrylic resins, black tea, transverse strength


2021 ◽  
Vol 25 (2) ◽  
pp. 108-113
Author(s):  
Ozlem Gurbuz Oflezer ◽  
Hakan Bahadır ◽  
Senem Ünver ◽  
Ceyhan Oflezer

Summary Background/Aim: Relining is defined as the procedure used to resurface the tissue side of a denture with new base material, thus producing an accurate adaptation is provided at the denture foundation area. During mastication, relined dentures have to withstand masticatory forces to prevent fracture. The aim of this study was to evaluate the flexural strength of acrylic resin denture base relined with different methods and materials. Material and Methods: Fourteen experimental groups and one control group were determined to consider different reline materials and processing methods. Acrylic resin specimens were prepared with the dimensions of 65× 10× 1.5 mm and reline materials (1.5 mm thickness) were placed on acrylic resins. Reline material was not used in control group specimens. Flexural strength values of relined and control specimens were measured with three-point bending test at a speed of 5 mm/min. Data were analyzed with using one way Anova and Student t tests. Results: The highest flexural strength values were shown in control group (86.51±1.08 MPa). There were significant differences among relined specimens (p< 0.05). For the relined specimens, the highest flexural strength values were found in the relined specimens with denture base material (77.90±1.93 MPa), and the lowest values were found in relined with autopolymerize acrylic material (59.81±1.50 MPa). Conclusions: Relining of the heat cure denture base material significantly decreases the flexural strength for all processing methods and materials.


2020 ◽  
Vol 5 (3) ◽  
pp. 126
Author(s):  
Gene Rizky Natalia Gunawan ◽  
Titik Ismiyati ◽  
Haryo Mustiko Dipoyono

Acrylic resin is a denture base material mostly used in the fabrication of removable partial denture and complete denture because it is easy to process, economical and aesthetically satisfying. However, the acrylic resin has a weakness i.e. residual monomer content which causes cytotoxic effect to human cells. Nano-silica coating could be used on the acrylic resin to reduce residual monomer content. The purpose of this study was to determine the effect of nano-silica coating concentration on the cytotoxicity of acrylic resin denture base material. Twenty-four acrylic resin disc-shaped specimens (5 mm in diameter and 2 mm in thickness) were divided into 4 groups (n=6), i.e. control, group with application of 0.5%,1%, and 2% nano silica coating. The specimens on the silica coating groups were silica coated using dip-coating method. After the coating was completed, the specimens were added into cell fibroblast culture (vero cell line). Cytotoxicity testswere done by MTT assay. The optical density was measured using ELISA plate reader to determine the percentage of cell viability. The highest mean of cell viability was shown in 0.5% concentration (96.78 ± 1.71) and the lowest mean was shown in the control group (80.32 ± 6.53). One-way ANOVA showed that there were significant differences among these groups. LSD tests showed that there was significant difference among all of the groups. This study concluded that nano silica coating concentration has a significant effect on the cytotoxicity of acrylic resin denture base materials.


2018 ◽  
Vol 30 (2) ◽  
pp. 5-9
Author(s):  
Zahraa S. Abed karkosh ◽  
Basima M.A. Hussien

Background: acrylic resin denture base consider a common denture base material for its acceptable cost, aesthetic and easy processing but still has disadvantages including easy of fracture and low impact strength. Material and method: The experimental group was prepared by addition of 15% phosphoric acid 2-hydroxyethyl methacrylate ester (PA2HEME) with polymethyl methacrylate monomer; the experimental groups was compared with the control one. The specimens were prepared according to ADA specification No. 12 with dimension 65 mm x 10 mm x2.5 mm (length x width x thickness respectively). The prepared specimens were tested by three-point flexural strength utilizing Instron Universal Testing Machine (WDW, Layree Technology Co.), Shore D hardness tester used to measure hardness test. Statistical analysis used student T- test, mean and standard deviation. Results: The result of PA2HEME group showed high significant reduction comparing to the control group for both transverse strength and hardness test. Conclusion: Mixing 15% of PA2HEME with 85% methyl methacrylate (MMA) can reduce the mechanical properties of new modified polymethyl methacrylate (PMMA) acrylic resin.


2019 ◽  
Vol 16 (2) ◽  
pp. 33
Author(s):  
Jovanna Andhara Arieputri ◽  
Dewi Kristiana ◽  
R. Rahardyan Parnaadji

Denture stomatitis is inflammation of the oral mucosa in contact with the denture base caused by the fungus Candida albicans. Denture stomatitis can be prevented by cleaning the dentures either mechanically or chemically. Mangosteen peel extract has been shown to inhibit the growth of C. albicans, but its effectiveness as a denture cleaning agent needs to be improved. One way to increase effectiveness is by combining chemical cleansing and mechanical cleansing through effervescent tablets. The aim of the study was to determine the effectiveness of mangosteen peel extract effervescent tablets as an acrylic denture cleaner against C. albicans. Previously, the effervescent tablets of mangosteen peel extract were made with concentrations of 30% and 60%. Heat cured acrylic resin samples were incubated into a test tube containing C. albicans suspension for 24 hours at 37oC. Furthermore, the samples were immersed in effervescent tablets of mangosteen peel extract for 15 and 30 minutes. The number of C. albicans cells was counted using a spectrophotometer. The results showed that there was a significant reduction in the number of C. albicans cells attached to the plate surface after immersion in 30% and 60% effervescent tablets of mangosteen peel extract (p <0.05). Mangosteen peel extract effervescent tablets 60% more decreased the number of C. albicans cells. The duration of immersion did not show significantly different results (p> 0.05). Effervescent tablets of 60% concentration of mangosteen peel extract soaked for 15 minutes were the most effective as an acrylic resin denture cleaner against C. albicans.


2018 ◽  
Vol 30 (1) ◽  
pp. 35 ◽  
Author(s):  
Edwin Tandra ◽  
Endang Wahyuningtyas ◽  
Erwan Sugiatno

Introduction: Acrylic resin is still the most commonly used denture base material due to its ideal properties. However, acrylic resin denture fractures are still considered a major unsolved problem thus the addition of nanoparticles as filler was performed to increase its mechanical properties. The purpose of this study was to discovered the effect of nanoparticles TiO2 on the flexural strength of acrylic resin denture plate. Method: This study used 27 heat-cured acrylic resin specimens sized 65 x 10 x 2.5 mm. The samples were divided into three concentration groups (n = 9), the control group; 1% of nanoparticles TiO2; and 3% of nanoparticles TiO2. The flexural strength was tested using the Universal Testing Machine. All data were analysed using the one-way ANOVA test with 95% confidence level then continued with the Least Significant Difference (LSD) test. Results: There were significant flexural strength differences in different concentration of nanoparticles TiO2. The highest flexural strength value was found in the 1% of nanoparticles TiO2 group (106.99 ± 6.09 MPa), whilst the lowest flexural strength value was found in the 3% of nanoparticles TiO2 group (91.64 ± 5.38 MPa). Significant flexural strength difference was found between the control group and the 1% of nanoparticles TiO2 group, and also between the 1% of nanoparticles TiO2 group with the 3% of nanoparticles TiO2 group (p < 0.05). Conclusion: From this study can be concluded that concentration of 1% of nanoparticles TiO2 was able to increase the flexural strength of acrylic resin denture plate.


2020 ◽  
Vol 5 (1) ◽  
pp. 36-43
Author(s):  
Gladis Aprilla Rizki ◽  
Sri Wahyuningsih Rais ◽  
Martha Mozartha

Alcoholic beverages can be consumed in any group age, and it may be consumed by an individual using denture. Fluid absorption by heat-cured acrylic resin as a material of a denture base was able to cause an increase in its surface roughness. Absorption of an organic solvent such as the ethanol in an alcoholic beverage(s) could even increase the effect. This study aimed to evaluate the effect of alcohol beverages on surface roughness of heat-cured acrylic resin denture base. Samples (n=24) were prepared from heat-cured acrylic resin (25x25x5 mm). They were divided into 4 groups and the pre-test surface roughness was measured. Samples of each group were immersed for 10 minutes into the solution (distilled water as the control group, beer, wine, and whiskey as the test groups). After stored in artificial saliva for 23 hours, the samples were immersed into the solution, completing a period of 24 hours. This procedure was performed for 7 consecutive days and the post-test surface roughness was measured. Data were statistically analyzed using the Kruskal-Walis test. There was a significant difference in surface roughness measurement before and after the immersion (p<0.05). Whiskey was most affecting the surface roughness of heat-cured acrylic resin denture base. Alcoholic beverages could increase the surface roughness of heat cure acrylic resin denture base. Keywords: Alcoholic beverages; Heat-cured acrylic denture base; Surface roughness


2017 ◽  
Vol 2 (3) ◽  
pp. 183
Author(s):  
Ardiansyah S. Pawinru ◽  
Andi Izham

Objective: Microorganisms are often found in the oral cavity is candida albicans approximately 40 % in the oral cavity. Candida albicans can penetrate the acrylic resin that can infect the soft tissue and is the cause of denture stomatitis therefore the disinfection pf denture base is an important factor that must be done. The purpose of the research is to determine how the effect of submersion denture base acrylic resin in a betel leaf exstract solution against growth candida albicans.Material and Methods: This research is an experimental laboratory with a longitudinal design (follow-up) study. The Sampling method used is Total Sampling. This study used a sample of 12 pieces of denture base material acrylic resin to be suspended candida albicans fungus for 1x24 hours at 37oC.Results: The number of candida albicans colonies n denture base acrylic resin which soaked betel leaf extract solution that the dilution 10-1with consentration 2.5% total colony count is 2 and the results 2.0 x 101 CFU/ml , on a control solution that the dilution 10-2 total colony 355 and the result 3.55x104 CFU/ml , that the dilution  10-3 total colony 62 and the result 6.2x104 CFU/ml.Conclusion: Betel leaf extract (piper linn) can inhibit the growth of candida albicans on denture base of acrylic resin, betel leaf extract (piper linn) 5% is a minimal anti-fungal power that can be used as a disinfectant solution in acrylic resin denture.


Sign in / Sign up

Export Citation Format

Share Document