scholarly journals Correlations of Fat Content in Human Milk with Fat Droplet Size and Phospholipid Species

Molecules ◽  
2021 ◽  
Vol 26 (6) ◽  
pp. 1596
Author(s):  
Beibei Duan ◽  
Eun-Sik Hong ◽  
Jung-Ah Shin ◽  
Yan Qin ◽  
Jeung-Hee Lee ◽  
...  
Keyword(s):  
Human Milk ◽  
Droplet Size ◽  
Positive Relationship ◽  
Fat Content ◽  
Globule Size ◽  
Group A ◽  
Fat Globule ◽  
Phospholipid Species

Fat globule size and phospholipid (PL) content in human milk (HM) were investigated. HM was classified into three groups depending on fat content (A < B < C). PL content (mg/100 g HM) was significantly higher in the C group (p < 0.05), indicating its positive relationship with HM fat content. When the PL content was normalized (mg/g fat), that of group A was significantly higher (p < 0.05) and fat droplet size in group C was slightly larger, suggesting that HM fat content is affected by fat droplet numbers to a larger extent than by fat droplet size. A correlation between PC and SM content in HM was observed regardless of fat content, while correlation between PE and either PC or SM increased in the order of C > B > A, hence the composition and content of PL species in HM varied according to its fat content.

551. Variations in the fat content of human milk during suckling

1954 ◽  
Vol 21 (2) ◽  
pp. 204-206 ◽  
Author(s):  
W. G. Whittlestone ◽  
Dawn R. Perrin
Keyword(s):  
Body Temperature ◽  
Human Milk ◽  
Milk Fat ◽  
Fat Content ◽  
Systematic Change ◽  
Fat Globules ◽  
Globule Size ◽  
Milk Fat Globules ◽  
Fat Globule ◽  
Human Milk Fat

It has been shown that human milk, like cow's milk, increases in fat content during suckling. The increase is not associated with any systematic change in fat globule size distribution. Human milk fat globules, like those of the cow, have been shown to cluster at body temperature. These facts support the theory that the increase in fat content during suckling is due to the fine ducts filtering out the larger globule clusters.

Variation of fat globule size and fatty acids in human milk in the first 30 days of lactation

2020 ◽  
Vol 100 ◽  
pp. 104567
Author(s):  
Wendi Jiang ◽  
Xue Zhang ◽  
Jin Cheng ◽  
Jie Song ◽  
Qingzhe Jin ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Human Milk ◽  
Globule Size ◽  
Fat Globule

scholarly journals Human milk-based fortifier is associated with less alteration of milk fat globule size than cow milk-based fortifier

PLoS ONE ◽  
2021 ◽  
Vol 16 (12) ◽  
pp. e0257491
Author(s):  
Yurika Yoshida ◽  
Minami Azuma ◽  
Haruhiro Kuwabara ◽  
Tokuo Miyazawa ◽  
Yuya Nakano ◽  
...  
Keyword(s):  
Human Milk ◽  
Milk Fat ◽  
Cow Milk ◽  
Very Preterm Infants ◽  
Very Preterm ◽  
Fortified Milk ◽  
Globule Size ◽  
Milk Fat Globule ◽  
Fat Globule ◽  
Feeding Tolerance

We aimed to evaluate if human milk-based fortifier (HMBF) affects human milk fat globule (MFG) size less than cow milk-based fortifier (CMBF), which may impact overall infant feeding tolerance. Measurements of donated human milk were performed before fortification as well as at 1 hour, 24 hours, and 48 hours after fortification with CMBF or HMBF. MFG size in each sample of fortified milk was measured by laser light scattering. MFG size in the fortified milks increased gradually over time. At 24 and 48 hours after fortification, MFG size in the milk with CMBF was larger than that in the milk with HMBF (4.8 ± 0.5 vs 4.3 ± 0.3 μm, p<0.01, 5.1 ± 0.7 vs 4.5 ± 0.4 μm, p = 0.03, respectively). HMBF is associated with less alteration of MFG size than CMBF. This may have an impact on feeding tolerance of very preterm infants.

Structure of the human milk fat globule

2013 ◽  
Vol 25 (10) ◽  
pp. 223-226 ◽  
Author(s):  
Cyrielle Garcia ◽  
Sheila Innis
Keyword(s):  
Human Milk ◽  
Milk Fat ◽  
Milk Fat Globule ◽  
Fat Globule ◽  
Human Milk Fat

scholarly journals Isolation and characterization of two individual glycoprotein components from human milk-fat-globule membranes

1982 ◽  
Vol 207 (1) ◽  
pp. 37-41 ◽  
Author(s):  
A Imam ◽  
D J Laurence ◽  
A M Neville
Keyword(s):  
Human Milk ◽  
Milk Fat ◽  
Sodium Dodecyl ◽  
Membrane Glycoproteins ◽  
Lectin Affinity Chromatography ◽  
Isolation And Characterization ◽  
Milk Fat Globule ◽  
Fat Globule ◽  
Milk Fat Globule Membranes ◽  
Human Milk Fat

Two individual glycoprotein components from human milk-fat-globule membranes (MFGM) has been purified by selectively extracting the membrane glycoproteins followed by lectin affinity chromatography and gel filtration on Sephadex G-200 in the presence of protein-disaggregating agents. The purified glycoprotein components, termed ‘epithelial-membrane glycoprotein’ (EMGP-155 and EMGP-39) have estimated molecular weights of 155 000 and 39 000 respectively, and yield a single band under reducing conditions on sodium dodecyl sulphate/polyacrylamide gel. EMGP-155 and EMGP-39 contain 21.0% and 7.0% carbohydrate by weight, with fucose (13.5%, 12.4%), mannose (3.7%, 6.2%), galactose (28.5%, 22.6%), N-acetylglucosamine (17.8%, 7.4%) and sialic acid (36.4%, 51.4%) of the carbohydrate moiety respectively. For both the glycoprotein components, aspartic and glutamic acid and serine are the major amino acid residues.

Radiation doses obtained from 99mTc-labelled human milk fat globule monoclonal antibodies

1993 ◽  
Vol 20 (2) ◽  
pp. 145-148
Author(s):  
M.M. Calitz ◽  
A. Van Aswegen ◽  
M.M.J. Van Der Merwe ◽  
M.G. Lötter
Keyword(s):  
Monoclonal Antibodies ◽  
Human Milk ◽  
Milk Fat ◽  
Radiation Doses ◽  
Milk Fat Globule ◽  
Fat Globule ◽  
Human Milk Fat

536. The physical properties of cow's milk as influenced by stage of lactation: The Size Distribution of Butterfat Globules

1954 ◽  
Vol 21 (1) ◽  
pp. 50-54 ◽  
Author(s):  
W. G. Whittlestone
Keyword(s):  
Physical Properties ◽  
Distribution Pattern ◽  
Size Distribution ◽  
Cow’S Milk ◽  
Sampling Device ◽  
Cow's Milk ◽  
Stage Of Lactation ◽  
Globule Size ◽  
Fat Globule ◽  
Milking Machine

An examination of the fat-globule size distribution pattern has been made throughout the lactation for one quarter of one cow, samples being taken at different stages in the milking process using a normal milking machine with sampling device attached.

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