scholarly journals Branched Chain Amino Acid Supplementation to a Hypocaloric Diet Does Not Affect Resting Metabolic Rate but Increases Postprandial Fat Oxidation Response in Overweight and Obese Adults after Weight Loss Intervention

Nutrients ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 4245
Author(s):  
Delicia Shu Qin Ooi ◽  
Jennifer Qiu Rong Ling ◽  
Fang Yi Ong ◽  
E Shyong Tai ◽  
Christiani Jeyakumar Henry ◽  
...  
Keyword(s):  
Weight Loss ◽  
Metabolic Rate ◽  
Dietary Intervention ◽  
Resting Metabolic Rate ◽  
Fat Oxidation ◽  
High Protein ◽  
Hypocaloric Diet ◽  
Weight Loss Intervention ◽  
Branched Chain ◽  
Standard Protein

Background: Branched chain amino acids (BCAA) supplementation is reported to aid in lean mass preservation, which may in turn minimize the reduction in resting metabolic rate (RMR) during weight loss. Our study aimed to examine the effect of BCAA supplementation to a hypocaloric diet on RMR and substrate utilization during a weight loss intervention. Methods: A total of 111 Chinese subjects comprising 55 males and 56 females aged 21 to 45 years old with BMI between 25 and 36 kg/m2 were randomized into three hypocaloric diet groups: (1) standard-protein (14%) with placebo (CT), (2) standard-protein with BCAA, and (3) high-protein (27%) with placebo. Indirect calorimetry was used to measure RMR, carbohydrate, and fat oxidation before and after 16 weeks of dietary intervention. Results: RMR was reduced from 1600 ± 270 kcal/day to 1500 ± 264 kcal/day (p < 0.0005) after weight loss, but no significant differences in the change of RMR, respiratory quotient, and percentage of fat and carbohydrate oxidation were observed among the three diet groups. Subjects with BCAA supplementation had an increased postprandial fat (p = 0.021) and decreased postprandial carbohydrate (p = 0.044) oxidation responses compared to the CT group after dietary intervention. Conclusions: BCAA-supplemented standard-protein diet did not significantly attenuate reduction of RMR compared to standard-protein and high-protein diets. However, the postprandial fat oxidation response increased after BCAA-supplemented weight loss intervention.

scholarly journals The effect of meal frequency and protein concentration on the composition of the weight lost by obese subjects

1981 ◽  
Vol 45 (1) ◽  
pp. 5-15 ◽  
Author(s):  
J. S. Garrow ◽  
Merril Durrant ◽  
Sandra Blaza ◽  
Deborah Wilkins ◽  
P. Royston ◽  
...  
Keyword(s):  
Weight Loss ◽  
Metabolic Rate ◽  
Protein Concentration ◽  
Resting Metabolic Rate ◽  
High Protein ◽  
Meal Frequency ◽  
N Loss ◽  
Lean Tissue ◽  
Protein Energy ◽  
Frequent Meal

1. Nitrogen balance, weight loss and resting metabolic rate were measured in thirty-eight obese inpatients on 3.4 MJ (800 kcal)/d diets over 3 weeks.2. All subjects were fed on 13% protein-energy in three rneals/d for the first week.3. In weeks 2 or 3, using a cross-over design, ten subjects were fed on 15 or 10% protein-energy as three meals/d; fourteen subjects were fed on five or one meal/d with 13%protein energy; and fourteen subjects were fed on 15% protein-energy as five meals/d or 10% protein-energy as one meal/d.4. N loss was least on the high-protein week and frequent-meal week: the largest difference was found when these effects were combined (P < 0.001).5. When protein-energy was held constant at 13% N loss decreased significantly (P < 0.01) between week 2 and 3, but when the protein-energy was manipulated there was no significant N conservation in the third week. This suggests that the protein:energy value is more important than meal frequency in the preservation of lean tissue.6. Weight loss was also least on the ‘high-protein’ week and ‘frequent-meal’ week, but this result reached significance only when the effects were combined (P < 0.05).7. Resting metabolic rate decreased with time but was not significantly altered by the dietary regimens.8. Therefore, during the first 3 weeks at an intake of 3.4 MJ/d, a diet with a high-protein concentration, fed as frequent small meals, is associated with better preservation of lean tissue than an isoenergetic diet with lower-protein concentration fed as fewer meals. There was no evidence that meal frequency or protein concentration affect the rate of fat loss.

scholarly journals Impact of Hepatic Steatosis on Resting Metabolic Rate and Metabolic Adaptation in Response to Intentional Weight Loss

2019 ◽  
Vol 3 (10) ◽  
pp. 1347-1355
Author(s):  
Vikrant P. Rachakonda ◽  
James P. DeLany ◽  
Erin E. Kershaw ◽  
Jaideep Behari
Keyword(s):  
Weight Loss ◽  
Metabolic Rate ◽  
Hepatic Steatosis ◽  
Resting Metabolic Rate ◽  
Metabolic Adaptation ◽  
Intentional Weight Loss

scholarly journals The associations of resting metabolic rate with chronic conditions and weight loss

2017 ◽  
Vol 7 (2) ◽  
pp. 70-76 ◽  
Author(s):  
R. A. G. Christensen ◽  
L. Raiber ◽  
S. Wharton ◽  
M. A. Rotondi ◽  
J. L. Kuk
Keyword(s):  
Weight Loss ◽  
Metabolic Rate ◽  
Chronic Conditions ◽  
Resting Metabolic Rate

Weight Loss and Weight Cycling in Amateur Wrestlers: Implications for Performance and Resting Metabolic Rate

1993 ◽  
Vol 3 (3) ◽  
pp. 245-260 ◽  
Author(s):  
Craig A. Horswill
Keyword(s):  
Weight Loss ◽  
Metabolic Rate ◽  
Resting Metabolic Rate ◽  
Recovery Period ◽  
Aerobic Performance ◽  
Anaerobic Performance ◽  
Rapid Weight Loss ◽  
Weight Class ◽  
Weight Cycling ◽  
Glycogen Depletion

Amateur wrestlers practice weight loss for ergogenic reasons. The effects of rapid weight loss on aerobic performance are adverse and profound, but the effects on anaerobic performance are equivocal Anaerobic performance—strength and power—may be the most relevant type of performance to the wrestler. Maintenance of or even small decrements in anaerobic performance may translate into improvements in performance relative to the weight class, the factor by which wrestlers are matched for competition. During the recovery period between the official weigh-in and competition, wrestlers achieve at least partial nutritional recovery, which appears to benefit performance. Successive bouts of (a) weight loss to make weight and (b) recovery for performance lead to weight cycling. There is speculation that weight cycling may contribute to chronic glycogen depletion, reductions in fat-free weight, a decrease in resting metabolic rate, and an increase in body fat. The latter two would augment the difficulty of losing weight for subsequent weigh-ins. Most research indicates that the suppressed resting metabolic rate with weight loss in wrestlers appears to be transient, but subsequent research is needed for confirmation.

scholarly journals Characterization of the Gut Microbiota in Individuals with Overweight or Obesity during a Real-World Weight Loss Dietary Program: A Focus on the Bacteroides 2 Enterotype

Biomedicines ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 16
Author(s):  
Rohia Alili ◽  
Eugeni Belda ◽  
Odile Fabre ◽  
Véronique Pelloux ◽  
Nils Giordano ◽  
...  
Keyword(s):  
Weight Loss ◽  
Gut Microbiota ◽  
Real World ◽  
Dietary Intervention ◽  
Streptococcus Thermophilus ◽  
High Protein ◽  
Microbiome Composition ◽  
Low Carbohydrate ◽  
Restriction Diet

Background: Dietary intervention is a cornerstone of weight loss therapies. In obesity, a dysbiotic gut microbiota (GM) is characterized by high levels of Bacteroides lineages and low diversity. We examined the GM composition changes, including the Bacteroides 2 enterotype (Bact2), in a real-world weight loss study in subjects following a high-protein hypocaloric diet with or without a live microorganisms (LMP) supplement. Method: 263 volunteers were part of this real-world weight loss program. The first phase was a high-protein low-carbohydrate calorie restriction diet with or without LMP supplements. Fecal samples were obtained at baseline and after 10% weight loss for 163 subjects. Metagenomic profiling was obtained by shotgun sequencing. Results: At baseline, the Bact2 enterotype was more prevalent in subjects with aggravated obesity and metabolic alterations. After weight loss, diversity increased and Bact2 prevalence decreased in subjects with lower GM diversity at baseline, notably in LMP consumers. Significant increases in Akkermansia muciniphila and Parabacteroides distasonis and significant decreases of Eubacterium rectale, Streptococcus thermophilus and Bifidobacterial lineages were observed after weight loss. Conclusion: Baseline microbiome composition is associated with differential changes in GM diversity and Bact2 enterotype prevalence after weight loss. Examining these signatures could drive future personalized nutrition efforts towards more favorable microbiome compositions.

Sign in / Sign up

Export Citation Format

Share Document