Predicting Oral Drug Absorption: Mini Review on Physiologically-Based Pharmacokinetic Models

Predictive Performance of Physiologically Based Pharmacokinetic Models for the Effect of Food on Oral Drug Absorption: Current Status

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12260 ◽

2017 ◽

Vol 7 (2) ◽

pp. 82-89 ◽

Cited By ~ 31

Author(s):

Mengyao Li ◽

Ping Zhao ◽

Yuzhuo Pan ◽

Christian Wagner

Keyword(s):

Drug Absorption ◽

Predictive Performance ◽

Current Status ◽

Oral Drug ◽

Pharmacokinetic Models ◽

Oral Drug Absorption ◽

Physiologically Based ◽

Effect Of Food ◽

Absorption Current

Physiologically-Based Pharmacokinetic Model on the Oral Drug Absorption in Roux-en-Y Gastric Bypass Bariatric Patients: Amoxicillin Tablet and Suspension

Molecular Pharmaceutics ◽

10.1021/acs.molpharmaceut.9b00870 ◽

2019 ◽

Vol 16 (12) ◽

pp. 5025-5034

Author(s):

Maiara Camotti Montanha ◽

Andréa Diniz ◽

Nuno Miguel Elvas Neves Silva ◽

Elza Kimura ◽

Paulo Paixão

Keyword(s):

Gastric Bypass ◽

Drug Absorption ◽

Pharmacokinetic Model ◽

Oral Drug ◽

Physiologically Based Pharmacokinetic Model ◽

Oral Drug Absorption ◽

Physiologically Based ◽

Bariatric Patients

Physiologically Based Pharmacokinetic Models in the Prediction of Oral Drug Exposure Over the Entire Pediatric Age Range—Sotalol as a Model Drug

The AAPS Journal ◽

10.1208/s12248-013-9555-6 ◽

2014 ◽

Vol 16 (2) ◽

pp. 226-239 ◽

Cited By ~ 45

Author(s):

Feras Khalil ◽

Stephanie Läer

Keyword(s):

Drug Exposure ◽

Oral Drug ◽

Pediatric Age ◽

Pharmacokinetic Models ◽

Physiologically Based ◽

Model Drug ◽

Age Range

Using Physiologically Based Pharmacokinetic (PBPK) Modeling to Evaluate the Impact of Pharmaceutical Excipients on Oral Drug Absorption: Sensitivity Analyses

The AAPS Journal ◽

10.1208/s12248-016-9964-4 ◽

2016 ◽

Vol 18 (6) ◽

pp. 1500-1511 ◽

Cited By ~ 12

Author(s):

Edwin Chiu Yuen Chow ◽

Arjang Talattof ◽

Eleftheria Tsakalozou ◽

Jianghong Fan ◽

Liang Zhao ◽

...

Keyword(s):

Drug Absorption ◽

Sensitivity Analyses ◽

Pbpk Modeling ◽

Oral Drug ◽

Oral Drug Absorption ◽

Pharmaceutical Excipients ◽

Physiologically Based ◽

The Impact ◽

Absorption Sensitivity

Using Physiologically-Based Pharmacokinetic Models to Incorporate Chemical and Non-Chemical Stressors into Cumulative Risk Assessment: A Case Study of Pesticide Exposures

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph9051971 ◽

2012 ◽

Vol 9 (5) ◽

pp. 1971-1983 ◽

Cited By ~ 7

Author(s):

Susan C. Wason ◽

Thomas J. Smith ◽

Melissa J. Perry ◽

Jonathan I. Levy

Keyword(s):

Risk Assessment ◽

Cumulative Risk ◽

Pharmacokinetic Models ◽

Pesticide Exposures ◽

Analysis of the impact of controlled release formulations on oral drug absorption, gut wall metabolism and relative bioavailability of CYP3A substrates using a physiologically-based pharmacokinetic model

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2014.10.018 ◽

2015 ◽

Vol 67 ◽

pp. 32-44 ◽

Cited By ~ 14

Author(s):

Andrés Olivares-Morales ◽

Yoshiteru Kamiyama ◽

Adam S. Darwich ◽

Leon Aarons ◽

Amin Rostami-Hodjegan

Keyword(s):

Controlled Release ◽

Drug Absorption ◽

Pharmacokinetic Model ◽

Relative Bioavailability ◽

Oral Drug ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based ◽

Controlled Release Formulations ◽

The Impact

Response to “The Link Between Pharmacodynamics and Physiologically Based Pharmacokinetic Models”

Clinical Pharmacology & Therapeutics ◽

10.1038/clpt.2012.216 ◽

2012 ◽

Vol 93 (2) ◽

pp. 152-152 ◽

Cited By ~ 5

Author(s):

A Rostami-Hodjegan

Keyword(s):

Pharmacokinetic Models ◽

In Vitro to In Vivo Extrapolation of Metabolic Rate Constants for Physiologically Based Pharmacokinetic Models

Toxicokinetics and Risk Assessment ◽

10.1201/b14275-9 ◽

2016 ◽

pp. 185-210

Author(s):

Gregory L. Kedderis

Keyword(s):

Metabolic Rate ◽

Rate Constants ◽

Pharmacokinetic Models ◽

Physiologically Based ◽

In Vivo Extrapolation

Pharmacokinetic/Physiologically Based Pharmacokinetic Models in Integrated Risk Information System Assessments

Toxicokinetics and Risk Assessment ◽

10.1201/b14275-16 ◽

2006 ◽

pp. 301-348 ◽

Cited By ~ 2

Author(s):

Robert De Woskin ◽

Chadwick Thompson ◽

Weihsueh Chiu ◽

Paul Schlosser ◽

Carolyn Smallwood ◽

...

Keyword(s):

Information System ◽

Risk Information ◽

Pharmacokinetic Models ◽

Integrated Risk ◽

Are Physiologically Based Pharmacokinetic Models Reporting the Right Cmax? Central Venous Versus Peripheral Sampling Site

The AAPS Journal ◽

10.1208/s12248-015-9796-7 ◽

2015 ◽

Vol 17 (5) ◽

pp. 1268-1279 ◽

Cited By ~ 9

Author(s):

Helen Musther ◽

Katherine L. Gill ◽

Manoranjenni Chetty ◽

Amin Rostami-Hodjegan ◽

Malcolm Rowland ◽

...

Keyword(s):

Sampling Site ◽

Pharmacokinetic Models ◽

Central Venous ◽

Physiologically Based ◽

The Right