scholarly journals Ex Vivo Determination of Broadband Absorption and Effective Scattering Coefficients of Porcine Tissue

Photonics ◽  
2021 ◽  
Vol 8 (9) ◽  
pp. 365
Author(s):  
Florian Bergmann ◽  
Florian Foschum ◽  
Leonie Marzel ◽  
Alwin Kienle
Keyword(s):  
Ex Vivo ◽  
Precise Determination ◽  
Integrating Sphere ◽  
Sample Type ◽  
Roughness Effects ◽  
Broadband Absorption ◽  
Porcine Tissue ◽  
Scattering Coefficients ◽  
Novel Approach

A novel approach for precise determination of the optical scattering and absorption properties of porcine tissue using an optimized integrating sphere setup was applied. Measurements on several sample types (skin, muscle, adipose tissue, bone, cartilage, brain) in the spectral range between 400 nm and 1400 nm were performed. Due to the heterogeneity of biological samples, measurements on different individual animals as well as on different sections for each sample type were carried out. For all samples, we used an index matching method to reduce surface roughness effects and to prevent dehydration. The derived absorption spectra were used to estimate the concentration of important tissue chromophores such as water, oxy- and deoxyhemoglobin, collagen and fat.

scholarly journals Determination of the optical properties of bovine liver tissue using integrating sphere technique

2018 ◽  
Vol 1 (1) ◽  
pp. 248-252
Author(s):  
Halil Arslan ◽  
Yasar Baris Dolukan
Keyword(s):  
Optical Properties ◽  
Liver Tissue ◽  
Tissue Sample ◽  
Bovine Liver ◽  
Integrating Sphere ◽  
Scattering Coefficients ◽  
Single Sphere ◽  
Microscope Slides ◽  
Good Agreement

The optical properties (absorption and reduced scattering coefficients, µa and µs’) of bovine liver tissue for 635 nm has been determined by using integrating sphere and inverse adding-doubling (IAD) techniques. For this purpose, total reflectance and total transmittance values of bovine liver tissue sample, which is placed between two microscope slides, have been measured by using single-sphere system. The measured values have been used as input parameters for IAD program to extract the µa and µs’ of the sample. In this study, µa and µs’ of bovine liver tissue for 635 nm have been determined to be 0.22 mm-1 and 0.51mm-1, respectively. These values, which yield 1.44 mm penetration depth, are in good agreement with the ones in the literature.

Novel approach for a precise determination of short-time intervals in ankle sprain experiments

2009 ◽  
Vol 42 (16) ◽  
pp. 2823-2825 ◽  
Author(s):  
Syn Schmitt ◽  
Mark Melnyk ◽  
Wilfried Alt ◽  
Albert Gollhofer
Keyword(s):  
Ankle Sprain ◽  
Precise Determination ◽  
Time Intervals ◽  
Novel Approach ◽  
Short Time

The Use of TMAH to Etch Silicon and Expose Metal Bridging Failures

2000 ◽  
Author(s):  
Mark Morris ◽  
James Mohr ◽  
Esteban Ortiz ◽  
Steven Englebretson
Keyword(s):  
Failure Mechanism ◽  
Schottky Diodes ◽  
Tetramethylammonium Hydroxide ◽  
Novel Approach ◽  
Failure Location ◽  
Metal Etching ◽  
Plastic Mold

Abstract Determination of metal bridging failures on plastic encapsulated devices is difficult due to the metal etching effects that occur while removing many of the plastic mold compounds. Typically, the acids used to remove the encapsulation are corrosive to the metals that are found within the device. Thus, decapsulation can result in removal of the failure mechanism. Mechanical techniques are often not successful due to damage that results in destruction of the die and failure mechanism. This paper discusses a novel approach to these types of failures using a silicon etch and a backside evaluation. The desirable characteristics of the technique would be to remove the silicon and leave typical device metals unaffected. It would also be preferable that the device passivation and oxides not be etched so that the failure location is not disturbed. The use of Tetramethylammonium Hydroxide (TMAH), was found to fit these prerequisites. The technique was tested on clip attached Schottky diodes that exhibited resistive shorting. The use of the TMAH technique was successful at exposing thin solder bridges that extruded over the edge of the die resulting in failure.

PRECISE DETERMINATION OF THE IRRATIONAL PRE-FERRED INTERFACE ORIENTATION BY TEM

2010 ◽  
Vol 46 (4) ◽  
pp. 411-417 ◽  
Author(s):  
Yang MENG ◽  
Lin GU ◽  
Wenzheng ZHANG
Keyword(s):  
Precise Determination ◽  
Interface Orientation

Nauwkeurige methode voor de aanwasbepaling van het grondvlak met behulp van de Pressler-boor

1968 ◽  
Vol 12 ◽  
Author(s):  
R. Goossens
Keyword(s):  
Basal Area ◽  
Precise Determination ◽  
Maximum Diameter ◽  
Precise Method ◽  
Maximum Radius ◽  
The Core ◽  
Two Parameters

A precise method for the determination of the increment of the  basal area using the PressIer bore. Refering to  previous research showing that the basal area of the corsica pine could be  characterized by an ellips, we present in this paper a precise method for the  determination of the increment of the basal area. In this method we determine  the direction of the maximum diameter, we measure this diameter and we take a  core in one of the points of tangency of the caliper with the measured tree.  The determination of the diameter perpendicular to the maximum diameter  finishes the work wich is to be done in the forest. From the classical  measurements effectuated on the core and from the measured diameters we can  then determine the form (V) and the excentricity (e). Substituting these two  parameters in the formula 2 or 2', we can also calculate the error of a  radius measured on the core with respect to the representative radius, This  error with them allow us to correct the measured value of the minimum or the  maximum radius and we will be able to do a precise determination of the  increment.

scholarly journals Marker for the pre-clinical development of bone substitute materials

2017 ◽  
Vol 3 (2) ◽  
pp. 711-715
Author(s):  
Michael de Wild ◽  
Simon Zimmermann ◽  
Marcel Obrecht ◽  
Michel Dard
Keyword(s):  
Bone Graft ◽  
Mechanical Stability ◽  
Clinical Performance ◽  
Ex Vivo ◽  
Region Of Interest ◽  
Defect Site ◽  
Novel Approach ◽  
Bone Substitute Materials ◽  
Clinical Experiments

AbstractThin mechanically stable Ti-cages have been developed for the in-vivo application as X-ray and histology markers for the optimized evaluation of pre-clinical performance of bone graft materials. A metallic frame defines the region of interest during histological investigations and supports the identification of the defect site. This standardization of the procedure enhances the quality of pre-clinical experiments. Different models of thin metallic frameworks were designed and produced out of titanium by additive manufacturing (Selective Laser Melting). The productibility, the mechanical stability, the handling and suitability of several frame geometries were tested during surgery in artificial and in ex-vivo bone before a series of cages was preclinically investigated in the female Göttingen minipigs model. With our novel approach, a flexible process was established that can be adapted to the requirements of any specific animal model and bone graft testing.

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