scholarly journals Electrospinning/Electrospray of Ferrocene Containing Copolymers to Fabricate ROS-Responsive Particles and Fibers

Polymers ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 2520
Author(s):  
Hoik Lee ◽  
Jiseob Woo ◽  
Dongwan Son ◽  
Myungwoong Kim ◽  
Won Il Choi ◽  
...  
Keyword(s):  
Deposition Process ◽  
Radical Copolymerization ◽  
Electrospinning Process ◽  
Random Copolymers ◽  
Oxygen Species ◽  
Stimuli Responsive ◽  
Sensitive Material ◽  
Free Radical Copolymerization ◽  
Varied Composition ◽  
Opening Up

We demonstrate an electrospray/electrospinning process to fabricate stimuli-responsive nanofibers or particles that can be utilized as stimuli-responsive drug-loaded materials. A series of random copolymers consisting of hydrophobic ferrocene monomers and hydrophilic carboxyl groups, namely poly(ferrocenylmethyl methacrylate-r-methacrylic acid) [poly(FMMA-r-MA)] with varied composition, was synthesized with free radical copolymerization. The morphologies of the resulting objects created by electrospray/electrospinning of the poly(FMMA-r-MA) solutions were effectively varied from particulate to fibrous structures by control of the composition, suggesting that the morphology of electrosprayed/electrospun copolymer objects was governed by its composition and hence, interaction with the solvent, highlighting the significance of the balance of hydrophilicity/hydrophobicity of the copolymer chain to the assembled structure. Resulting particles and nanofibers exhibited largely preserved responsiveness to reactive oxygen species (ROS) during the deposition process, opening up the potential to fabricate ROS-sensitive material with various desirable structures toward different applications.

Multiple stimuli-responsive selenium-functionalized biodegradable starch-based hydrogels

Soft Matter ◽  
2018 ◽  
Vol 14 (6) ◽  
pp. 921-926 ◽  
Author(s):  
Tongbing Sun ◽  
Caizhen Zhu ◽  
Jian Xu
Keyword(s):  
Free Radical ◽  
Drug Release ◽  
Biomedical Applications ◽  
Radical Copolymerization ◽  
Enzyme Hydrolysis ◽  
Stimuli Responsive ◽  
Free Radical Copolymerization ◽  
Redox Responsive

Biodegradable diselenide cross-linked starch-based hydrogels, composed of starch chain backbones with an enzyme hydrolysis property and selenium-containing cross-linkers with a redox responsive cleavage property, were synthesizedviafree radical copolymerization and used as stimuli-responsive drug release materials for biomedical applications.

Synthesis and Electrochemical Characterization of New Thioether- and Ferrocene-Containing Copolymers

2004 ◽  
Vol 57 (3) ◽  
pp. 207 ◽  
Author(s):  
Murray V. Baker ◽  
Jinzhen Lu ◽  
Touma B. Issa ◽  
Pritam Singh ◽  
Jelica Strauch
Keyword(s):  
Cyclic Voltammetry ◽  
Modified Electrodes ◽  
Spectroscopic Studies ◽  
Radical Copolymerization ◽  
Random Copolymers ◽  
Free Radical Copolymerization ◽  
Surface Modified ◽  
Random Nature ◽  
Surface Modified Electrodes

Random copolymers containing both ferrocene groups and thioether groups were synthesized by free-radical copolymerization of vinylferrocene and 2-(methylthio)ethyl methacrylate, and the random nature of the copolymerization was confirmed by spectroscopic studies. Copolymers with ferrocene-to-thioether ratios of 8 : 1 and 1.2 : 1 were used to modify the surfaces of gold electrodes, and the behaviours of the resulting surface-modified electrodes were investigated by cyclic voltammetry. The SMEs based on the copolymers showed superior stability compared to SMEs based on poly(vinylferrocene), with the most stable SMEs being formed from the copolymer with the higher proportion of thioether groups.

scholarly journals Self-Association Behavior of Cell Membrane-Inspired Amphiphilic Random Copolymers in Water

Polymers ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 327 ◽  
Author(s):  
Maho Ohshio ◽  
Kazuhiko Ishihara ◽  
Shin-ichi Yusa
Keyword(s):  
Aqueous Solutions ◽  
Fluorescence Probe ◽  
Nmr Relaxation ◽  
Radical Copolymerization ◽  
Degree Of Polymerization ◽  
Water Soluble ◽  
Random Copolymers ◽  
Free Radical Copolymerization ◽  
Association Behavior ◽  
Self Association

Water-soluble and amphiphilic random copolymers (P(MPC/DMAx)) composed of hydrophilic 2-methacryloyloxyethyl phosphorylcholine (MPC) and hydrophobic n-dodecyl methacrylate (DMA) were prepared via reversible addition-fragmentation chain transfer (RAFT) controlled radical polymerization. The compositions of DMA unit (x) in the copolymer were in the range of 0 to 38 unit mol %. The degree of polymerization of P(MPC/DMAx) was adjusted to about 200. Since the monomer reactivity ratios of MPC and DMA are 1.01 and 1.00, respectively, ideal free radical copolymerization occurred. In aqueous solutions, interpolymer aggregation occurred due to the hydrophobic pendant n-dodecyl groups. The aggregation number (Nagg) increased with an increasing x. The mobilities of the DMA and MPC pendant groups in aqueous solutions were restricted, as confirmed by 1H NMR relaxation time measurements, because a part of the MPC units were trapped in the hydrophobic microdomain formed from the pendant n-dodecyl groups. The polarity of the hydrophobic microdomain formed from P(MPC/DMA38) in water was similar to that of ethyl acetate according to fluorescence probe experiments. No specific interactions were found in water between P(MPC/DMAx) and bovine serum albumin because the surface of the interpolymer aggregates contained only hydrophilic MPC units.

Cyclohexyl Methacrylate with Tetra (Ethylene Glycol) Dimethacrylate in Tertahydrofuran Radical Copolymerization

2009 ◽  
Vol 609 ◽  
pp. 63-67 ◽  
Author(s):  
Asmahane Fasla ◽  
Seghier Ould Kada ◽  
Zoubida Seghier ◽  
Alain Périchaud
Keyword(s):  
Ethylene Glycol ◽  
Specific Activity ◽  
13C Nmr Spectroscopy ◽  
Radical Copolymerization ◽  
Ethylene Glycol Dimethacrylate ◽  
Random Copolymers ◽  
Glycol Dimethacrylate ◽  
Free Radical Copolymerization ◽  
Tetrahydrofuran Solution ◽  
Cyclohexyl Methacrylate

Free-radical copolymerization of cyclohexyl methacrylate (CHMA) and tetra (ethylene glycol) dimethacrylate (TtEGDMA) were carried out at 60 °C in tetrahydrofuran solution in presence of 2,2-azobisisobutyronitrile. The random copolymers were prepared with nominal crosslinking ratios, X of 1, 5 and 10% mol TtEGDMA / mol CHMA. The copolymers were characterized by 13C NMR spectroscopy. The copolymers was characterized by 13C RMN analysis and determined the copolymers composition. The monomer reactivity ratios r1 (TtEGDMA) and r2 (CHMA) were determined with the linearized copolymerization equations of the Fineman–Ross methods (r1 = 1.77 and r2 = 0.48) and Kelen–Tüdös (r1 = 1.81 and r2 = 0.46). Parameters of Alfrey-Price Q1 = - 1.10 (specific activity) and e1= - 0.64 (polarity) for TtEGDMA.

scholarly journals Novel Self-Healing Metallocopolymers with Pendent 4-Phenyl-2,2′:6′,2″-terpyridine Ligand: Kinetic Studies and Mechanical Properties

Polymers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1760
Author(s):  
Rose K. Baimuratova ◽  
Gulzhian I. Dzhardimalieva ◽  
Evgeniy V. Vaganov ◽  
Valentina A. Lesnichaya ◽  
Gulsara D. Kugabaeva ◽  
...  
Keyword(s):  
Critical Role ◽  
Specific Effect ◽  
Kinetic Studies ◽  
Radical Copolymerization ◽  
Self Healing ◽  
Free Radical Copolymerization ◽  
Polymer Hydrogels ◽  
Close Proximity ◽  
Metal Group ◽  
Metal Polymer

We report here our successful attempt to obtain self-healing supramolecular hydrogels with new metal-containing monomers (MCMs) with pendent 4-phenyl-2,2′:6′,2″-terpyridine metal complexes as reversible moieties by free radical copolymerization of MCMs with vinyl monomers, such as acrylic acid and acrylamide. The resulting metal-polymer hydrogels demonstrate a developed system of hydrogen, coordination and electron-complementary π–π stacking interactions, which play a critical role in achieving self-healing. Kinetic data show that the addition of a third metal-containing comonomer to the system decreases the initial polymerization rate, which is due to the specific effect of the metal group located in close proximity of the active center on the growth of radicals.

High-pressure free-radical copolymerization of ethene and 2-ethylhexyl acrylate

1996 ◽  
Vol 197 (12) ◽  
pp. 4119-4134 ◽  
Author(s):  
Michael Buback ◽  
Thomas Dröge ◽  
Alex Van Herk ◽  
Frank-Olaf Mähling
Keyword(s):  
High Pressure ◽  
Free Radical ◽  
Radical Copolymerization ◽  
Free Radical Copolymerization
Sign in / Sign up

Export Citation Format

Share Document