scholarly journals In-Situ One-Step Direct Loading of Agents in Poly(acrylic acid) Coating Deposited by Aerosol-Assisted Open-Air Plasma

Polymers ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 1931
Author(s):  
Gabriel Morand ◽  
Pascale Chevallier ◽  
Cédric Guyon ◽  
Michael Tatoulian ◽  
Diego Mantovani

In biomaterials and biotechnology, coatings loaded with bioactive agents are used to trigger biological responses by acting as drug release platforms and modulating surface properties. In this work, direct deposition of poly(acrylic acid) coatings containing various agents, such as dyes, fluorescent molecules, was achieved by aerosol-assisted open-air plasma. Using an original precursors injection strategy, an acrylic acid aerosol was loaded with an aqueous aerosol and deposited on silicon wafers. Results clearly showed that agents dissolved in the aqueous aerosol were successfully entrapped in the final coating. The effect of aerosols concentration, flow rate, and treatment time, on the coating morphology and the amount of entrapped agents, was also investigated. It was demonstrated that this process has the potential to entrap a tunable amount of any sensible water-soluble agent without altering its activity. To the best of our knowledge, this is the first time that the loading of an aqueous aerosol in coatings deposited by plasma from a liquid aerosol precursor is reported. This innovative approach complements plasma deposition of coatings loaded with bioactive agents from aqueous aerosols with the use of non-volatile liquid precursors.

Langmuir ◽  
2018 ◽  
Vol 34 (47) ◽  
pp. 14342-14346 ◽  
Author(s):  
Xiaole Hu ◽  
Chan-Jin Kim ◽  
Shine K. Albert ◽  
So-Jung Park

2010 ◽  
Vol 53 (3) ◽  
pp. 623-628 ◽  
Author(s):  
Hortensia Ortega-Ortiz ◽  
Baltazar Gutiérrez-Rodríguez ◽  
Gregorio Cadenas-Pliego ◽  
Luis Ibarra Jimenez

The antimicrobial activity of chitosan and water soluble interpolyelectrolyte complexes of poly(acrylic acid)-chitosan was studied. Chitosans of two different molecular weights were tested at different concentration for 0.5 to 5 g·L-1 as antimicrobial agents against P. aeruginosa and P. oleovorans. In both cases, the best microbial inhibition was obtained with the concentration of 5 g·L-1. However, the interpolyelectrolyte complexes of poly(acrylic acid)-chitosan with composition φ =2 produced higher antibacterial activity than the two chitosans at the concentration of 0.5 g·L-1. The NPEC2 complex was more effective than chitosans. This could be attributed to the number of moles of the amino groups of chitosan and the carboxylic acid groups of the interpolyelectrolyte complexes poly(acrylic acid).


Langmuir ◽  
1998 ◽  
Vol 14 (7) ◽  
pp. 1554-1559 ◽  
Author(s):  
Guochang Wang ◽  
Fred Henselwood ◽  
Guojun Liu

2010 ◽  
Vol 2 (4) ◽  
pp. 1177-1183 ◽  
Author(s):  
Alexandre Garcia ◽  
Thomas Berthelot ◽  
Pascal Viel ◽  
Alice Mesnage ◽  
Pascale Jégou ◽  
...  

2017 ◽  
Vol 5 (7) ◽  
pp. 3434-3446 ◽  
Author(s):  
Mingyue Zhang ◽  
Lihua Song ◽  
Haifeng Jiang ◽  
Shu Li ◽  
Yifei Shao ◽  
...  

In order to achieve the reutilization of waste biomass soybean dregs, a low-cost hydrogel, soybean dregs–poly(acrylic acid) (SESD–PAA) was prepared through a one-step reaction.


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