scholarly journals Particulate Matter Short-Term Exposition, Mobility Trips and COVID-19 Diffusion: A Correlation Analyses for the Italian Case Study at Urban Scale

2021 ◽  
Vol 13 (8) ◽  
pp. 4553
Author(s):  
Armando Cartenì ◽  
Furio Cascetta ◽  
Luigi Di Francesco ◽  
Felisia Palermo
Keyword(s):  
Air Quality ◽  
Prolonged Exposure ◽  
Term Effect ◽  
Short Term ◽  
Italian Case ◽  
Correlation Analyses ◽  
Global Pandemic ◽  
Outdoor Environments ◽  
Definition Of

The conjecture discussed in this paper was that the daily number of certified cases of COVID-19 is direct correlated to the average particular matter (PM) concentrations observed several days before when the contagions occurred (short-term effect), and this correlation is higher for areas with a higher average seasonal PM concentration, as a measure of prolonged exposure to a polluted environment (long-term effect). Furthermore, the correlations between the daily COVID-19 new cases and the mobility trips and those between the daily PM concentrations and mobility trips were also investigated. Correlation analyses were performed for the application case study consisting in 13 of the main Italian cities, through the national air quality and mobility monitoring systems. Data analyses showed that the mobility restrictions performed during the lockdown produced a significant improvement in air quality with an average PM concentrations reduction of about 15%, with maximum variations ranging between 25% and 42%. Estimation results showed a positive correlation (stronger for the more highly polluted cities) between the daily COVID-19 cases and both the daily PM concentrations and mobility trips measured about three weeks before, when probably the contagion occurred. The obtained results are original, and if confirmed in other studies, it would lay the groundwork for the definition of the main context variables which influenced the COVID-19 spread. The findings highlighted in this research also supported by the evidence in the literature and allow concluding that PM concentrations and mobility habits could be considered as potential early indicators of COVID-19 circulation in outdoor environments. However, the obtained results pose significant ethical questions about the proper urban and transportation planning; the most polluted cities have not only worst welfare for their citizens but, as highlighted in this research, could lead to a likely greater spread of current and future respiratory and/or pulmonary health emergencies. The lesson to be learned by this global pandemic will help planners to better preserve the air quality of our cities in the post-COVID-19 era.

scholarly journals Tackling distribution-related shortages of medicines: An Italian case study evaluated in the European Union framework

2019 ◽  
Vol 3 ◽  
pp. 239920261985685 ◽  
Author(s):  
Domenico Di Giorgio ◽  
Giuseppe Scrofina ◽  
Barbara Scognamiglio ◽  
Nadia Di Carluccio ◽  
Romina Tulimiero ◽  
...  
Keyword(s):  
European Union ◽  
Ad Hoc ◽  
The European Union ◽  
Short Term ◽  
European Regulation ◽  
Italian Case ◽  
Set Up ◽  
Definition Of

Availability of human medicines is affected by problems associated with both manufacturing and distribution-related issues. The lack of definition of “shortages” or “unavailability” of medicines in European regulation represents an obstacle to the set up of proper preventive and counteracting measures. In this review, we describe how, within this framework, Italy started a program of shared activities, involving central and local authorities, police forces, and private stakeholders’ associations through an “ ad hoc technical forum,” that reduced the extent of the problem, at least in the short term, as demonstrated through some indicators defined by considering the key medicines affected by unavailability due to distribution-related issues. These measures should be strengthened and complemented with others so as to ensure their effectiveness in the long term.

Long-term regulation of hexose uptake by isoproterenol in cultured 3T3 adipocytes

1985 ◽  
Vol 248 (6) ◽  
pp. E706-E711 ◽  
Author(s):  
J. P. van Putten ◽  
H. M. Krans
Keyword(s):  
Protein Synthesis ◽  
Prolonged Exposure ◽  
Term Effect ◽  
Long Term Effects ◽  
Fat Cell ◽  
Short Term ◽  
Long Term Effect ◽  
Short Term Exposure ◽  
Hexose Uptake

Catecholamines are known to have short-term regulatory effects on fat cell hexose uptake. We examined the long-term effects of catecholamines on the insulin-sensitive 2-deoxyglucose (dGlc) uptake in cultured 3T3-L1 adipocytes. Prolonged exposure (48 h) to isoproterenol (beta-adrenergic agonist) stimulated the basal dGlc uptake up to 90%. The effect was specific, time, concentration, and protein synthesis dependent and reversible. The effect of insulin was unaltered and superimposed on the increase in basal dGlc uptake. The long-term effect of isoproterenol was mimicked by epinephrine, dibutyryl cAMP (DBcAMP), and 1-methyl-3-isobutylxanthine (IBMX). By contrast, short-term exposure to isoproterenol (and epinephrine) induced a protein synthesis-independent increase in basal dGlc uptake (30%) not accompanied by an increase in insulin responsiveness. Moreover, on short-term basis, DBcAMP and IBMX suppressed both the basal and insulin-stimulated uptake up to 50%. Determination of the intracellular nonphosphorylated dGlc during the uptake and of the hexokinase activity revealed that the long-term effect of isoproterenol was most likely due to alterations low in dGlc transport. In conclusion, long-term regulators of hexose uptake are in cultured 3T3-L1 adipocytes, isoproterenol, and other cAMP stimulators. The long-term effect is independent from the short-term regulatory effect of the agents and from the effect of insulin.

scholarly journals Short-term variation in air quality associated with firework events: A case study

2003 ◽  
Vol 5 (2) ◽  
pp. 260-264 ◽  
Author(s):  
Khaiwal Ravindra ◽  
Suman Mor ◽  
C. P. Kaushik
Keyword(s):  
Air Quality ◽  
Short Term ◽  
Term Variation

scholarly journals The Importance of “Contextualisation” in Small and Medium-Sized Firms Valuation: Evidences from an Italian Case Study

2017 ◽  
Vol 13 (1) ◽  
pp. 70
Author(s):  
Damiano Montani ◽  
Francesco Perrini ◽  
Daniele Gervasio ◽  
Andrea Pulcini
Keyword(s):  
Financial Flows ◽  
Italian Case ◽  
Company Value ◽  
Proper Definition ◽  
Theory Of Value ◽  
Definition Of ◽  
A Company ◽  
Correct Data

The valuation of a small or medium-sized enterprise through subjective methods, may not exclude a correct contextualisation of the data forming the information base of the estimate. “Contextualisation” refers to the general overview of all those elements that allow a proper definition of the enterprise’s background. All of this serves in the analysis for the correct data necessary for the determination of values such as the economic and financial flows to discount, the timeframe of analysis and the discount rate. Without a correct contextualisation, it is not possible to reach a correct measurement of the company value in accordance with the studies on the “theory of value”. After observing that “contextualisation” has not been widely studied till now for the theory of value, the present work analyses the incidence on the measurement of the company value, showing with an empirical case the different results that may be reached on the basis of the contextualisation of data. Hence, a correct “contextualisation” is crucial for the proper valuation of a company. Academic researches should take more carefully into consideration, this aspect concerning the valuation of a company and in particular, define more accurately the implementing rules in the assessment methods.

Study of the waste disposal effect on air quality: the Italian case study

2021 ◽  
Vol 1 (1) ◽  
pp. 1
Author(s):  
Daniele Sofia ◽  
Nicoletta Lotrecchiano ◽  
Aristide Giuliano ◽  
Renato Ciampa
Keyword(s):  
Air Quality ◽  
Waste Disposal ◽  
Italian Case
Sign in / Sign up

Export Citation Format

Share Document