scholarly journals The prevalence and association of major ECG abnormalities with clinical characteristics and the outcomes of real-life heart failure patients—Heart Failure Registries of the ESC

2021 ◽  
Author(s):  
Agata Tymińska ◽  
Krzysztof Ozierański ◽  
Paweł Balsam ◽  
Agnieszka Kapłon-Cieślicka ◽  
Cezary Maciejewski ◽  
...  
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Giosafat Spitaleri ◽  
Josep Lupón ◽  
Mar Domingo ◽  
Evelyn Santiago-Vacas ◽  
Pau Codina ◽  
...  

AbstractTo assess mortality trends at 1 and 3 years from 2001 to 2018 in a real-life cohort of HF outpatients from different etiologies with depressed and preserved LVEF. A total of 2368 consecutive patients with HF (mean age 66.4 ± 12.9 years, 71% men, 15.4% with preserved LVEF) admitted to a HF clinic from August 2001 to September 2018 were included in the study. Patients were divided into five quintiles (Q) according to the period of admission. Trends for all-cause and cardiovascular mortality from Q1 to Q5 were assessed by linear regression. Patients with LVEF < 50% had a progressive decrease in the rates of all-cause and cardiovascular death at 1 year (12.1% in Q1 to 6.5% in Q5, p = 0.003; and 8.4% in Q1 to 3.8% in Q5, p = 0.007, respectively) and 3 years (30.5% in Q1 to 17.0% in Q5, p = 0.003; and 23.9% in Q1 to 9.8% in Q5, p = 0.003, respectively). These trends remained significant after adjusting for clinical characteristics and risk. No significant trend in mortality was observed in patients with LVEF ≥ 50%. In a cohort of real-life ambulatory patients with HF, mortality progressively declined in patients with LVEF < 50%, but the same trend was not observed in patients with preserved LVEF.


2021 ◽  
Vol 7 ◽  
Author(s):  
Wilson Matthew Raffaello ◽  
Joshua Henrina ◽  
Ian Huang ◽  
Michael Anthonius Lim ◽  
Leonardo Paskah Suciadi ◽  
...  

Heart failure is currently one of the leading causes of morbidity and mortality. Patients with heart failure often present with acute symptoms and may have a poor prognosis. Recent evidence shows differences in clinical characteristics and outcomes between de novo heart failure (DNHF) and acute decompensated chronic heart failure (ADCHF). Based on a better understanding of the distinct pathophysiology of these two conditions, new strategies may be considered to treat heart failure patients and improve outcomes. In this review, the authors elaborate distinctions regarding the clinical characteristics and outcomes of DNHF and ADCHF and their respective pathophysiology. Future clinical trials of therapies should address the potentially different phenotypes between DNHF and ADCHF if meaningful discoveries are to be made.


Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Maira Tristao Parra ◽  
Meredith A Pung ◽  
Kathleen Wilson ◽  
Christopher Pruitt ◽  
Barry H Greenberg ◽  
...  

Hypothesis: insufficiently active heart failure patients will report poorer QoL, more fatigue and depressive mood compared to active patients. Aims: To characterize clinical characteristics and health-related behaviors according to physical activity (PA). Also, to explore predicting factors of quality of life (QoL). Methods: Cross-sectional analysis of a cohort of Stage B HF patients. PA classification was set as active, moderately active or insufficiently active, according to the LTEQ questionnaire. For QoL, the SF-36 questionnaire was used. ANOVAS, Chi-Square tests or likelihood ratios and unadjusted multiple regression models were calculated. Significance was set at p ≤ 0.05. Results: In this cohort, 277 HF patients completed the PA questionnaire. The prevalence of active patients was higher than moderately active and insufficiently active (53.3% vs 15.2% and 29.6%), respectively. Younger age (p = 0.044), lower waist circumference (WC) (p = 0.002), and lower waist-to-hip ratio (p = 0.046) were associated with being active. The prevalence of Type II diabetes mellitus (T2DM) in the active groups was significantly lower (p = 0.001). Physically active groups had cases of mild LV enlargement (1.4% and 7.5%, respectively), while no cases were observed among insufficiently active patients (p = 0.017). PA was positively associated with less fatigue (p= 0.002), more vigor (p = 0.001), more self-efficacy (p < 0.001), and better quality of life (p = 0.002). Patients who were less physically active had more inflammation (CRP, p = 0.015; IL-6, p <0.001; TNF-α: p = 0.033, and IL-1ra, p = 0.001). WC (β =-0.16, p = 0.008), glucose (β =-0.12, p < 0.001) and fatigue (β = - 0.39, p < 0.001) predicted general health perception (R 2 = 0.449). For physical functioning (high scores reflects performing PA without limitations due to health), WC (β = - 0.28, p = 0.001), sleep (β = - 1.50, p = 0.003) and fatigue (β = - 0.32, p = 0.018) were significant predictors (R 2 = 0.422); while age (β = 0.36, p <0.001) physical activity (β = 0.051, p = 0.055), sleep (β = 0.50, p =0.046), fatigue (β = -0.37, p <0.001) and depression (β = -1.12, p <0.001) predicted emotional well-being (R 2 = 0.696). Conclusion: Physically active heart failure patients had a better anthropometric profile and lower prevalence of T2DM. In this cohort, PA was not a significant predictor for general and physical functioning, but it remained relevant for predicting emotional well-being.


2018 ◽  
Vol 08 (04) ◽  
Author(s):  
Paweł Balsam ◽  
Krzysztof Ozierański ◽  
Agnieszka Kapłon-Cieślicka ◽  
Sonia Borodzicz ◽  
Agata Tymińska ◽  
...  

2017 ◽  
Vol 72 (2) ◽  
pp. 180-187
Author(s):  
Marek Hudak ◽  
Michal Kerekanic ◽  
Silvia Misikova ◽  
Erika Komanova ◽  
Alexander Boho ◽  
...  

2013 ◽  
Vol 24 (4) ◽  
pp. 339-345 ◽  
Author(s):  
Alicia Conde-Martel ◽  
Francesc Formiga ◽  
Carmen Pérez-Bocanegra ◽  
Arola Armengou-Arxé ◽  
Alberto Muela-Molinero ◽  
...  

2015 ◽  
Vol 17 (4) ◽  
pp. 374-384 ◽  
Author(s):  
Kadhim Sulaiman ◽  
Prashanth Panduranga ◽  
Ibrahim Al-Zakwani ◽  
Alawi A. Alsheikh-Ali ◽  
Khalid F. AlHabib ◽  
...  

2013 ◽  
Vol 24 (7) ◽  
pp. 677-683 ◽  
Author(s):  
Jesús Casado ◽  
Manuel Montero ◽  
Francesc Formiga ◽  
Margarita Carrera ◽  
Agustín Urrutia ◽  
...  

2006 ◽  
Vol 6 (1) ◽  
Author(s):  
Sean P Collins ◽  
Christopher J Lindsell ◽  
W Frank Peacock ◽  
Daniel C Eckert ◽  
Jeff Askew ◽  
...  

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