In December 2019 the first cases of atypical pneumonia caused by a novel coronavirus
SARS-CoV-2 were reported in Wuhan, China. This new infection was called coronavirus disease
2019 (COVID-19). SARS-CoV-2 is primarily transmitted human-to-human via direct contact and
via the air-respiratory droplets and/or aerosols. The clinical manifestations of COVID-19 could
range from asymptomatic or mild non-specific symptoms to severe pneumonia with multiple
organ failure and death. The virus spread rapidly to almost all the countries in the world
within a few months, and on the 11th of March 2020, the World Health Organization (WHO)
announced the COVID-19 pandemic. Since then, a dynamic increase in the number of COVID-19
infections and deaths has been recorded worldwide. The COVID-19 pandemic is accelerating
and causing annex tensive impact on the functioning of health care and is also leading to an
economic crisis in the world. Today, it is difficult to ultimately assess the long-term effects
of the pandemic, although it is known that they will be experienced for decades. Therefore,
the most important goal is to stop the pandemic and develop an effective vaccine against
SARS-CoV-2. Using the ClinicalTrials.gov and World Health Organization databases, we shed
light on the current worldwide clinical and pre-clinical trials in search for a COVID-19 vaccine.