Faculty Opinions recommendation of Compensatory function of Pyk2 protein in the promotion of focal adhesion kinase (FAK)-null mammary cancer stem cell tumorigenicity and metastatic activity.

2011 ◽  
Author(s):  
Andrew Gilmore ◽  
Fiona Foster
Keyword(s):  
Stem Cell ◽  
Cancer Stem Cell ◽  
Focal Adhesion Kinase ◽  
Focal Adhesion ◽  
Mammary Cancer ◽  
Metastatic Activity

A phase 2 study of defactinib (VS-6063), a cancer stem cell inhibitor that acts through inhibition of focal adhesion kinase (FAK), in patients with KRAS-mutant non-small cell lung cancer.

2014 ◽  
Vol 32 (15_suppl) ◽  
pp. TPS8126-TPS8126 ◽  
Author(s):  
David E. Gerber ◽  
Suresh S. Ramalingam ◽  
Daniel Morgensztern ◽  
Ronan Joseph Kelly ◽  
Timothy Francis Burns ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Stem Cell ◽  
Cancer Stem Cell ◽  
Small Cell Lung Cancer ◽  
Focal Adhesion Kinase ◽  
Focal Adhesion ◽  
Small Cell ◽  
Phase 2 ◽  
Small Cell Lung ◽  
Phase 2 Study
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