Faculty Opinions recommendation of An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB.

2010 ◽  
Author(s):  
Filippo Giancotti ◽  
Ilaria Esposito
Keyword(s):  
Prostate Cancer ◽  
Tumor Suppressor ◽  
Metastatic Prostate Cancer ◽  
Nuclear Factor Kappab ◽  
Nuclear Factor

scholarly journals An oncogene–tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-κB

2010 ◽  
Vol 16 (3) ◽  
pp. 286-294 ◽  
Author(s):  
Junxia Min ◽  
Alexander Zaslavsky ◽  
Giuseppe Fedele ◽  
Sara K McLaughlin ◽  
Elizabeth E Reczek ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Tumor Suppressor ◽  
Metastatic Prostate Cancer ◽  
Nuclear Factor Κb ◽  
Nuclear Factor

scholarly journals Transcriptional activation of cyclooxygenase-2 by tumor suppressor p53 requires nuclear factor-kappaB

Oncogene ◽  
2006 ◽  
Vol 25 (42) ◽  
pp. 5708-5718 ◽  
Author(s):  
V Benoit ◽  
E de Moraes ◽  
N A Dar ◽  
E Taranchon ◽  
V Bours ◽  
...  
Keyword(s):  
Tumor Suppressor ◽  
Transcriptional Activation ◽  
Cyclooxygenase 2 ◽  
Nuclear Factor Kappab ◽  
Nuclear Factor ◽  
Tumor Suppressor P53

Abstract 4465: Glypican-1: A tumor suppressor or an oncogene in human bone metastatic prostate cancer cells

2017 ◽  
Author(s):  
Nhat D. Quach ◽  
Matthew Eggert ◽  
Deepraj Ghosh ◽  
Michelle R. Dawson ◽  
Robert Arnold ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Tumor Suppressor ◽  
Cancer Cells ◽  
Metastatic Prostate Cancer ◽  
Human Bone ◽  
Prostate Cancer Cells

scholarly journals Circulating Cell-Free DNA-Based Detection of Tumor Suppressor Gene Copy Number Loss and Its Clinical Implication in Metastatic Prostate Cancer

2021 ◽  
Vol 11 ◽  
Author(s):  
Xiaoxi Dong ◽  
Tiantian Zheng ◽  
Minhua Zhang ◽  
Chao Dai ◽  
Lili Wang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Tumor Suppressor ◽  
Tumor Suppressor Gene ◽  
Cancer Progression ◽  
Liquid Biopsy ◽  
Copy Number ◽  
Metastatic Prostate Cancer ◽  
Suppressor Gene ◽  
Gene Copy ◽  
Copy Number Loss

Current liquid biopsy assays lack sufficient sensitivity to detect copy number loss, which limits the interrogation of critical tumor suppressor gene deletions during cancer progression and treatment. Here we describe a liquid biopsy assay with improved sensitivity for detection of copy number loss in blood samples with low levels of circulating tumor DNA, and demonstrate its utility by profiling PTEN, RB1, and TP53 genetic loss in metastatic prostate cancer patients.

scholarly journals Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

Cancer Cell ◽  
2003 ◽  
Vol 4 (3) ◽  
pp. 209-221 ◽  
Author(s):  
Shunyou Wang ◽  
Jing Gao ◽  
Qunying Lei ◽  
Nora Rozengurt ◽  
Colin Pritchard ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Tumor Suppressor ◽  
Tumor Suppressor Gene ◽  
Metastatic Prostate Cancer ◽  
Suppressor Gene ◽  
Specific Deletion
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