The Earth system has maintained habitable conditions for life over geological periods of time. These conditions include an equable global temperature, enough atmospheric carbon dioxide to fuel photosynthesis, and sufficient nutrients to grow. Furthermore, for at least the past 370 million years there has been enough atmospheric oxygen to support complex, mobile animal life, but not so much that wildfires decimated vegetation. ‘Regulation’ introduces the ways in which the biogeochemical cycles of the Earth system are self-regulated, how they are coupled to the Earth’s climate, and how scientists study this regulation.