Faculty Opinions recommendation of Assessment of bone synthetic activity in inflammatory lesions and syndesmophytes in patients with ankylosing spondylitis: the potential role of 18F-fluoride positron emission tomography-magnetic resonance imaging.

2015 ◽  
Author(s):  
Conny van der Laken
Keyword(s):  
Magnetic Resonance Imaging ◽  
Positron Emission Tomography ◽  
Potential Role ◽  
Emission Tomography ◽  
Synthetic Activity ◽  
Resonance Imaging ◽  
Inflammatory Lesions ◽  
Positron Emission ◽  
18F Fluoride

scholarly journals Imaging the role of toll-like receptor 4 on cell proliferation and inflammation after cerebral ischemia by positron emission tomography

2016 ◽  
Vol 36 (4) ◽  
pp. 702-708 ◽  
Author(s):  
Ana Moraga ◽  
Vanessa Gómez-Vallejo ◽  
María Isabel Cuartero ◽  
Boguslaw Szczupak ◽  
Eneko San Sebastián ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Positron Emission Tomography ◽  
Cerebral Ischemia ◽  
Emission Tomography ◽  
Toll Like Receptor ◽  
Resonance Imaging ◽  
Toll Like Receptor 4 ◽  
Positron Emission ◽  
Neuroimaging Techniques

The influence of toll-like receptor 4 on neurogenesis and inflammation has been scarcely explored so far by using neuroimaging techniques. For this purpose, we performed magnetic resonance imaging and positron emission tomography with 3′-deoxy-3′-[18F]fluorothymidine and [11C]PK11195 at 2, 7, and 14 days following cerebral ischemia in TLR4+/+ and TLR4−/− mice. MRI showed similar infarction volumes in both groups. Despite this, positron emission tomography with 3′-deoxy-3′-[18F]fluorothymidine and [11C]PK11195 evidenced an increase of neurogenesis and a decrease of inflammation in TLR4−/− mice after ischemia. These results evidence the versatility of neuroimaging techniques to monitor the role of toll-like receptor 4 after cerebral ischemia.

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